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The protein encoded by HTATSF1 functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal HTATSF1 Primary Antibody für IF, WB - ABIN968708 : Parada, Roeder: A novel RNA polymerase II-containing complex potentiates Tat-enhanced HIV-1 transcription. in The EMBO journal 1999 (PubMed) Show all 3 Pubmed References
Human Polyclonal HTATSF1 Primary Antibody für ELISA, WB - ABIN451602 : Zhou, Deng, Lacoste, Park, Pumfery, Kashanchi, Brady, Kumar: Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription. in Journal of virology 2004 (PubMed)
Dog (Canine) Polyclonal HTATSF1 Primary Antibody für WB - ABIN2774210 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)
CA150 (zeige TCERG1 Antikörper) FF domains recognize multiple sites within the Tat-SF1 protein conforming to the consensus motif (D/E)(2/5)-F/W/Y-(D/E)(2/5).
This study validates Tat-SF1 as an HDF (zeige Vcan Antikörper) in CD4 (zeige CD4 Antikörper)+ T cell-derived SupT1 cells.
these findings suggest that Tat-SF1 functions independently in transcription and splicing of cellular genes.
These results support the notion that Tat (zeige TAT Antikörper)-induced neuropathogenesis is mediated by multiple mechanisms involving both intracellular and extracellular Tat (zeige TAT Antikörper) protein.
phosphorylated by P-TEFb (zeige CCNT1 Antikörper) kinase during HIV-1 transcription in Tat (zeige TAT Antikörper)/TAR (zeige RBM8A Antikörper) dependent manner
Intracellular HIV-1 Tat (zeige TAT Antikörper) protein represses constitutive LMP2 (zeige PSMB9 Antikörper) transcription increasing proteasome activity by interfering with the binding of IRF-1 (zeige IRF1 Antikörper) to STAT1 (zeige STAT1 Antikörper)
Tat-SF1 is not required for regulating HIV-1 transcription, but is required for maintaining the ratios of different classes of HIV-1 transcripts.
The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.
HIV-1 Tat specific factor 1 , HIV TAT specific factor 1 , HIV Tat-specific factor 1 , HTATSF1 protein , HIV Tat-specific factor 1 homolog , cofactor required for Tat activation of HIV-1 transcription