HESX Homeobox 1 (HESX1) ELISA Kits

HESX1 encodes a conserved homeobox protein that is a transcriptional repressor in the developing forebrain and pituitary gland. Zusätzlich bieten wir Ihnen HESX Homeobox 1 Antikörper (25) und HESX Homeobox 1 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
HESX1 8820 Q9UBX0
Anti-Ratte HESX1 HESX1 498575  
HESX1 15209 Q61658
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$875.60
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Maus
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$875.60
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Weitere ELISA Kits für HESX Homeobox 1 Interaktionspartner

Human HESX Homeobox 1 (HESX1) Interaktionspartner

  1. HESX1 mutations cause variable clinical features in congenital hypopituitarism patients, which suggests an influence of modifier genes or environmental factors on the phenotype

  2. A novel heterozygous mutation in the HESX1 gene and a novel homozygous mutation in the PROP1 (zeige PROP1 ELISA Kits) gene were detected in 2 pedigrees with combined pituitary hormone (zeige CGA ELISA Kits) deficiency

  3. investigated the specific mutations in PROP1 (zeige PROP1 ELISA Kits), POU1F1 (zeige POU1F1 ELISA Kits), LHX3 (zeige LHX3 ELISA Kits), and HESX1 genes in patients with combined pituitary hormone (zeige CGA ELISA Kits) deficiency (CPHD) in Turkey

  4. Data indicate that HESX1, LHX4 (zeige LHX4 ELISA Kits) and SOX3 (zeige SOX3 ELISA Kits) polymorphisms may be associated with pituitary stalk interruption syndrome (PSIS).

  5. expand the phenotypic spectrum of HESX1 mutations in Kallman syndrome.

  6. Data show no mutations in HESX1, PROP1 (zeige PROP1 ELISA Kits), and POU1F1 (zeige POU1F1 ELISA Kits) genes, seven different mutations in CTNNB1 (zeige CTNNB1 ELISA Kits) in 8/16 patients, and hyperexpression of miR (zeige MLXIP ELISA Kits)-150.

  7. A c.357+3G>A mutation prevents the generation of one of the alternative isoforms normally produced by the wild-type allele, predicting a truncated HESX1 protein.

  8. A novel HESX1 causative mutation was found in a consanguineous family, and two LHX4 (zeige LHX4 ELISA Kits) mutations were present in familial Pituitary stalk interruption syndrome.

  9. Mutations in the PROP1 (zeige PROP1 ELISA Kits) and HESX1 genes were not identified in these patients with sporadic growth hormone (zeige GH1 ELISA Kits) defiency, combined pituitary hormone (zeige CGA ELISA Kits) deficiency and septo-optic dysplasia.

  10. A large cohort of patients with schizencephaly, some with features of septo-optic dysplasia, were sequenced for mutations in LHX2 (zeige LHX2 ELISA Kits), HESX1 and SOX2 (zeige SOX2 ELISA Kits).

Mouse (Murine) HESX Homeobox 1 (HESX1) Interaktionspartner

  1. Hesx1 plays a significant role in sustaining pluripotency in embryonic stem cells.Hesx1 transcriptionally suppresses differentiation-related genes.

  2. Wnt (zeige WNT2 ELISA Kits) inhibition during the first day has larger impact on the activation of Hesx1 and Six3, suggesting that in embryos Wnt (zeige WNT2 ELISA Kits) inhibition caused by Dkk1 (zeige DKK1 ELISA Kits) contributes greatly in the establishment of the anterior forebrain precursor.

  3. Variability in Hes1 expression therefore helps to explain why STAT3 (zeige STAT3 ELISA Kits) responsiveness varies between individual ES cells, and this in turn helps to explain why pluripotent cells commit to differentiate asynchronously..

  4. Transcriptional profiling of anterior forebrain precursors from mouse embryos expressing eGFP from the Hesx1 locus provides molecular evidence supporting a novel function of Hesx1 in mediating repression of Wnt (zeige WNT2 ELISA Kits)/beta-catenin (zeige CTNNB1 ELISA Kits) target activation.

  5. Studies suggest that TLE1 and TLE3 might also play roles independent of HESX1 by interacting with other transcription factors like PROP1 (zeige PROP1 ELISA Kits).

  6. Data suggest that formation of a heterodimer between HESX1 and PROP1 (zeige PROP1 ELISA Kits) allows HESX1 to become active, and that PROP1 (zeige PROP1 ELISA Kits) then replaces HESX1 to advance to the middle stage of pituitary development.

  7. A novel inducible element, activated by contact with Rathke's pouch, is present in the regulatory region of the Hesx1 homeobox (zeige PRRX1 ELISA Kits) gene.

  8. the domains of Hes-1 needed to block adipogenesis coincide with those necessary for transcriptional repression.

  9. Conserved regulatory elements establish the dynamic expression of Rpx in early development.

  10. The absence of Hesx1 leads to a posterior transformation of the anterior forebrain (AFB) during mouse development.

HESX Homeobox 1 (HESX1) Antigen-Profil

Beschreibung des Gens

This gene encodes a conserved homeobox protein that is a transcriptional repressor in the developing forebrain and pituitary gland. Mutations in this gene are associated with septooptic dysplasia, HESX1-related growth hormone deficiency, and combined pituitary hormone deficiency.

Genbezeichner und Symbole assoziert mit HESX Homeobox 1 (HESX1) ELISA Kits

  • HESX homeobox 1 (HESX1) Antikörper
  • homeobox expressed in ES cells 1 pseudogene (LOC100351827) Antikörper
  • HESX homeobox 1 (Hesx1) Antikörper
  • homeobox gene expressed in ES cells (Hesx1) Antikörper
  • ANF Antikörper
  • CPHD5 Antikörper
  • HES-1 Antikörper
  • HESX1 Antikörper
  • RGD1563858 Antikörper
  • Rpx Antikörper

Bezeichner auf Proteinebene für HESX Homeobox 1 (HESX1) ELISA Kits

Rathke pouch homeobox , hAnf , homeobox expressed in ES cells 1 , homeobox protein ANF , homeobox, ES cell expressed 1 , homeo box (expressed in ES cells) 1 , homeo box gene expressed in ES cells , anterior-restricted homeobox protein , rathke pouch homeo box

GENE ID SPEZIES
8820 Homo sapiens
100351827 Oryctolagus cuniculus
100967444 Pan paniscus
747229 Pan troglodytes
498575 Rattus norvegicus
15209 Mus musculus
100008708 Oryctolagus cuniculus
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