Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like Proteine (GNL3L)

The protein encoded by GNL3L appears to be a nucleolar GTPase that is essential for ribosomal pre-rRNA processing and cell proliferation. Zusätzlich bieten wir Ihnen GNL3L Antikörper (65) und GNL3L Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
GNL3L 54552 Q9NVN8
GNL3L 237107 Q6PGG6
Ratte GNL3L GNL3L 100034253  
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Escherichia coli (E. coli) Human His-SUMO Tag 100 μg Anmelden zum Anzeigen 11 Days
$411.40
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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GNL3L Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) Interaktionspartnern

Human Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) Interaktionspartner

  1. GNL3L-LDOC1 (zeige LDOC1 Proteine) interplay regulates cell proliferation through the modulation of NF-kappaB (zeige NFKB1 Proteine) pathway during tumorigenesis.

  2. the present study provides evidence that GNL3L is exported from the nucleus in CRM1 (zeige XPO1 Proteine) dependent manner and the nuclear localization of GNL3L is important to promote 'S' phase progression during cell proliferation.

  3. GNL3L depletion impairs ribosome production without inducing appreciable DNA damage. During evolution, GNL3L retained the role of the ancestral gene in ribosome biosynthesis, whereas the paralogous nucleostemin (zeige E2IG3 Proteine) acquired a novel genome-protective function.

  4. differences in the relative nucleostemin (zeige E2IG3 Proteine) protein and mRNA levels may reflect the degree of proliferation of mesnchymal stem cells and can be used to characterize in vitro expansion capabilities

  5. GNL3L bound MDM2 (zeige MDM2 Proteine) in vivo, stabilizing MDM2 (zeige MDM2 Proteine) and preventing its ubiquitylation. GNL3L depletion upregulated specific p53 (zeige TP53 Proteine) targets (Bax (zeige BAX Proteine), 14-3-3sigma and p21 (zeige CDKN1A Proteine)).

  6. analysis uncovers an important role for Grn1p/GNL3L within this unique group of nucleolar GTPases

  7. GNL3L is composed of distinct modules, each of which plays a specific role in molecular interactions for its nucleolar retention and subsequent function(s) within the nucleolus

Mouse (Murine) Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L) Interaktionspartner

  1. work reveals a novel mechanism that negatively regulates the transcriptional function of ERRgamma (estrogen-related receptor (zeige ESRRG Proteine))by GNL3L through coactivator competition.

  2. GNL3L mediates the mitotic increase of TRF1 (zeige TERF1 Proteine) protein and promotes the metaphase-to-anaphase transition.

GNL3L Protein Überblick

Protein Überblick

The protein encoded by this gene appears to be a nucleolar GTPase that is essential for ribosomal pre-rRNA processing and cell proliferation. Two transcript variants encoding the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit GNL3L

  • guanine nucleotide binding protein-like 3 (nucleolar)-like (gnl3l)
  • guanine nucleotide binding protein-like 3 (nucleolar)-like S homeolog (gnl3l.S)
  • G protein nucleolar 3 like (GNL3L)
  • guanine nucleotide binding protein-like 3 (nucleolar)-like (Gnl3l)
  • G protein nucleolar 3 like (Gnl3l)
  • BC020354 Protein
  • flj10613 Protein
  • flj10613l Protein
  • si:dkey-13a21.8 Protein
  • SI:zK13A21.8 Protein
  • zgc:110536 Protein

Bezeichner auf Proteinebene für GNL3L

guanine nucleotide-binding protein-like 3-like protein , guanine nucleotide binding protein-like 3 (nucleolar)-like , guanine nucleotide-binding protein-like 3-like protein-like , novel GTPase

GENE ID SPEZIES
442932 Danio rerio
496093 Xenopus laevis
100465620 Ailuropoda melanoleuca
100603832 Nomascus leucogenys
54552 Homo sapiens
507679 Bos taurus
237107 Mus musculus
100034253 Rattus norvegicus
480933 Canis lupus familiaris
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