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The protein encoded by E2IG3 may interact with p53 and may be involved in tumorigenesis. Zusätzlich bieten wir Ihnen Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Proteine (6) und Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 136 products:
Mouse (Murine) Polyclonal E2IG3 Primary Antibody für WB - ABIN1881380
Hirai, Romanova, Kellner, Verma, Rayner, Asakura, Kikyo: Post-mitotic role of nucleostemin as a promoter of skeletal muscle cell differentiation. in Biochemical and biophysical research communications 2010
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Human Monoclonal E2IG3 Primary Antibody für BI, IHC (f) - ABIN2689866
Kafienah, Mistry, Williams, Hollander: Nucleostemin is a marker of proliferating stromal stem cells in adult human bone marrow. in Stem cells (Dayton, Ohio) 2006
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Human Polyclonal E2IG3 Primary Antibody für IHC (p), IP - ABIN151112
Okamoto, Yasukawa, Nguyen, Kasim, Maida, Possemato, Shibata, Ligon, Fukami, Hahn, Masutomi: Maintenance of tumor initiating cells of defined genetic composition by nucleostemin. in Proceedings of the National Academy of Sciences of the United States of America 2011
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Human Polyclonal E2IG3 Primary Antibody für ELISA, WB - ABIN4341079
Yoshida, Fujimoto, Kudoh, Nagata, Nakayama, Shinohara, Ito: Nucleostemin affects the proliferation but not differentiation of oral squamous cell carcinoma cells. in Cancer science 2011
Human Monoclonal E2IG3 Primary Antibody für ELISA, WB - ABIN1724769
Meng, Hsu, Tsai: GNL3L depletion destabilizes MDM2 and induces p53-dependent G2/M arrest. in Oncogene 2011
The nucleolar GTP-binding (zeige RND2 Antikörper) proteins Gnl2 (zeige GNL2 Antikörper) and nucleostemin are required for retinal neurogenesis in developing zebrafish.
In addition, migration and invasion demonstrated significant inhibition in Nucleostemin-deficient cells. Furthermore, the knockdown of Nucleostemin dramatically suppressed xenograft progression in BALB/c nude mice. Our findings suggest that Nucleostemin is associated with malignancy in an ovarian cancer SKOV-3 cell line.
Identified a positive correlation between up-regulation of nucleostemin and human glioma cell proliferation and that knocking-down nucleostemin alleviated glioma proliferation by reducing beta-Catenin (zeige CTNNB1 Antikörper) transportation into the nucleus.
Relative expression of GNL3 in synovial tissue and fluid samples was significantly higher in the osteoarthritic group as compared to the non-osteoarthritic group.
The expression level of GNL3 was examined in 89 human gastric cancer samples using immunohistochemistry (IHC) staining. GNL3 in gastric cancer tissues was significantly upregulated compared with paracancerous tissues.
over-expression of GNL3 and SKA3 (zeige SKA3 Antikörper) in the PC-3 (zeige PCSK1 Antikörper) human prostate cancer cell line decreased in vitro cell migration and invasion
p53 (zeige TP53 Antikörper) activation by inauhzin via inhibiting SIRT1 (zeige SIRT1 Antikörper), also inhibits cellular IMPDH2 (zeige IMPDH2 Antikörper) activity, reduces the levels of cellular GTP (zeige AK3 Antikörper) and GTP-binding (zeige RND2 Antikörper) nucleostemin, thus representing in a new anti-cancer strategy.
overexpression of NS suppressed ARF (zeige CDKN2A Antikörper) polyubiquitination by its E3 ligase Ubiquitin Ligase for ARF (zeige CDKN2A Antikörper) and elongated its half-life, whereas knockdown of NS led to the decrease of ARF (zeige CDKN2A Antikörper) levels
Silence of nucleostemin inhibit cell proliferation through up-regulating p21 (zeige CDKN1A Antikörper) expression and nucleostemin may be involved in the pathogenesis of esophageal squamous cell carcinoma.
It is concluded that nucleostemin expression could not be specific in a certain type of cells in colon cancer cell line HT29.
Data shows that the NS protein expression status was positively correlated with both ER and HER2 (zeige ERBB2 Antikörper) status and was a powerful prognostic factor.
Nucleostemin expression participates in the preservation of the viability and integrity of embryonic stem cells.
nucleostemin protects hematopoietic stem cells (HSCs) from DNA damage accumulation and is required for the maintenance of HSCs.
Mechanistic studies performed in mouse embryonic fibroblast cells showed that loss of nucleostemin triggers DNA damage and growth arrest independently of the p53 (zeige TP53 Antikörper) status or rRNA synthesis
Nucleostemin in the maintenance of ESC self-renewal, demonstrate the importance of rapid transit through G1 for this process, and expand the known classes of reprogramming factors.
NS functions downstream of Myc (zeige MYC Antikörper) as a rate-limiting regulator of cell proliferation and transformation.
NS undergoes a ubiquitin- and MDM2 (zeige MDM2 Antikörper)-independent proteasomal degradation when intracellular GTP (zeige AK3 Antikörper) levels are markedly reduced
a complex composed of TERT (zeige TERT Antikörper), BRG1 (zeige SMARCA4 Antikörper), and NS/GNL3L (zeige GNL3L Antikörper) maintains the function of tumor initiating cells
Reactive oxygen species regulate nucleostemin oligomerization and protein degradation.
analysis of nucleolar localization of stem cell protein (zeige TAL1 Antikörper) nucleostemin
Nucleostemin has a unique ability, derived from an ancestral function, to control the proliferation rate of stem/progenitor cells in vivo independently of p53.
Nucleostemin functions in early amphibian development to control cell proliferation of neural progenitor cells.
The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene.
guanine nucleotide-binding protein-like 3
, nucleostemin-like protein
, guanine nucleotide binding protein-like 3 (nucleolar)
, guanine nucleotide-binding protein-like 3-like
, E2-induced gene 3 protein
, estradiol-induced nucleotide binding protein
, novel nucleolar protein 47
, nucleolar GTP-binding protein 3