Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2) ELISA Kits

GGA2 encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. Zusätzlich bieten wir Ihnen Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 Antikörper (42) und Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus GGA2 GGA2 74105 Q6P5E6
Anti-Ratte GGA2 GGA2 293455  
Anti-Human GGA2 GGA2 23062 Q9UJY4
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Weitere ELISA Kits für Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 Interaktionspartner

Mouse (Murine) Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2) Interaktionspartner

  1. GGA2 binds to the internal DXXLL motif of the LRP9

Human Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2) Interaktionspartner

  1. These data indicate that clathrin is required for the function of AP-1 (zeige FOSB ELISA Kits)- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane.

  2. GGA2 mediates a vital function that cannot be compensated for by GGA1and/or GGA3 (zeige GGA3 ELISA Kits).

  3. endocytosis and intracellular transport of memapsin 2 (zeige BACE ELISA Kits), mediated by its cytosolic domain, may involve the binding of GGA1 (zeige GGA1 ELISA Kits) and GGA2

  4. Results demonstrate that cargo proteins contribute to the recruitment of GGA2 onto membranes and to the formation of GGA-positive clathrin-coated vesicles.

  5. p56 (zeige IFIT1 ELISA Kits) tightly cooperates with the GGAs in the sorting of cathepsin D (zeige CTSD ELISA Kits) to lysosomes, probably by enabling the movement of GGA-containing transport carriers.

  6. GGA2 is recruited to the trans-Golgi network independently of the other Golgi-localized, gamma-ear-containing, ARF-binding proteins and is required for the efficient sorting of lysosomal enzymes

  7. GGA overexpression causes various sorting defects as measured by recycling of CD-MPR, internalization of transferrin receptor, and the subcellular localization of proteins like Tsg101, ubiquitin, and Hrs.

Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 2 (GGA2) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated vesicle assembly.

Genbezeichner und Symbole assoziert mit GGA2

  • golgi associated, gamma adaptin ear containing, ARF binding protein 2 (Gga2) Antikörper
  • golgi associated, gamma adaptin ear containing, ARF binding protein 2 (GGA2) Antikörper
  • 1200007E24Rik Antikörper
  • mKIAA1080 Antikörper
  • VEAR Antikörper

Bezeichner auf Proteinebene für GGA2

ADP-ribosylation factor-binding protein GGA2 , gamma-adaptin-related protein 2 , golgi-localized, gamma ear-containing, ARF-binding protein 2 , VHS domain and ear domain of gamma-adaptin , VHS domain and ear domain-containing protein , golgi associated, gamma adaptin ear containing, ARF binding protein 2

GENE ID SPEZIES
74105 Mus musculus
293455 Rattus norvegicus
23062 Homo sapiens
608555 Canis lupus familiaris
100524333 Sus scrofa
517031 Bos taurus
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