Glutamate Receptor, Metabotropic 1 (GRM1) ELISA Kits

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Zusätzlich bieten wir Ihnen Metabotropic Glutamate Receptor 1 Antikörper (177) und Metabotropic Glutamate Receptor 1 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
GRM1 2911 Q13255
GRM1 14816 P97772
GRM1 24414 P23385
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Top Metabotropic Glutamate Receptor 1 ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.058 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$736.84
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Ratte 1.0 ng/mL 25-500 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Maus 1.0 ng/mL 25-500 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Human < 0.058 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
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Huhn
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Kaninchen
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Meerschweinchen
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Schwein
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Schaf
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Hund
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$707.14
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Am meisten referenzierte Metabotropic Glutamate Receptor 1 ELISA Kits

  1. Human Metabotropic Glutamate Receptor 1 ELISA Kit für Sandwich ELISA - ABIN420429 : Bovenschen, Spijkers, Wensink, Schellens, van Domselaar, van Baarle: Elevated granzyme M-expressing lymphocytes during cytomegalovirus latency and reactivation after allogeneic stem cell transplantation. in Clinical immunology (Orlando, Fla.) 2014 (PubMed)

Weitere ELISA Kits für Metabotropic Glutamate Receptor 1 Interaktionspartner

Human Glutamate Receptor, Metabotropic 1 (GRM1) Interaktionspartner

  1. Fyn (zeige FYN ELISA Kits) binds to mGluR1a at a consensus binding motif located in the intracellular C-terminus (CT) of mGluR1a in vitro. Active Fyn (zeige FYN ELISA Kits) phosphorylates mGluR1a at a conserved tyrosine residue in the CT region. In cerebellar neurons and transfected HEK293T cells, Fyn (zeige FYN ELISA Kits)-mediated tyrosine phosphorylation of mGluR1a is constitutively active and facilitates surface expression of mGluR1a and potentiates mGluR1a postreceptor signaling.

  2. Age-dependent increase in metabotropic glutamate (zeige GRIN1 ELISA Kits) receptor type 1 availability in several brain regions may exist predominantly in males.

  3. Missense Mutation in GRM1 gene is associated with Spinocerebellar Ataxia Type 44.

  4. our findings suggest that pharmacological manipulation of mglur1 should be explored as an exciting new approach for the treatment of a variety of human cerebellar ataxias.

  5. a missense variant was found in GRM1 gene, while in the second family, a frameshift alteration was identified in TRMT1, both of which were found to co-segregate with the intellectual disability.

  6. It has the intrinsic ability to form a heteromeric complex with adenosine A1 receptor (zeige ADORA1 ELISA Kits) and mutually modulate signaling.

  7. These data demonstrate that the approaches commonly used to study mGlu1 receptor function and signaling in other systems may be inappropriate for studying mGlu1 receptor-mediated melanoma cell viability.

  8. Our results are likely relevant to human breast cancer, highlighting a putative role of mGluR1 in the pathophysiology of breast cancer and the potential of mGluR1 as a novel therapeutic target.

  9. elevated glutamate (zeige GRIN1 ELISA Kits) secretion and mGluR1 expression play a role in Kaposi's sarcoma associated herpesvirus induced cell proliferation

  10. alpha-actinin-4 (zeige ACTN4 ELISA Kits) is a novel group 1 mGluR (zeige GRM8 ELISA Kits)-interacting partner that orchestrates spine dynamics and morphogenesis in neurons.

Mouse (Murine) Glutamate Receptor, Metabotropic 1 (GRM1) Interaktionspartner

  1. Study states that metabotropic glutamate (zeige GRIN1 ELISA Kits) receptor subtype 1 (mGluR1) is critical for elimination of surplus climbing fiber-Purkinje cell synapses in the cerebellum, retinogeniculate synapses require mGluR1 for maintenance of mature connectivity.

  2. Study shows that blocking of metabotropic glutamate (zeige GRIN1 ELISA Kits) type 5 receptor (mGlu5 (zeige GRM5 ELISA Kits)) reduced the dysregulation of glutamate (zeige GRIN1 ELISA Kits) transmission and improved motor coordination in the metabotropic glutamate (zeige GRIN1 ELISA Kits) type 1 receptor (Grm1crv4) mouse model of cerebellar ataxia SCAR13.

  3. These findings demonstrate that mGlu1 receptors play a key role in excitotoxic degeneration of retinal ganglion cell

  4. this work reveals novel functions of mGlu1 receptors in the bone and indicates that in osteoblasts mGlu1 receptors are necessary for production of normal bone matrix, longitudinal bone growth, and normal skeletal development.

  5. mGluR1 activation at the onset of reperfusion induces cardioprotection and might represent a putative strategy to prevent ischaemia-reperfusion injury.

  6. These findings demonstrate a deleterious positive feedback loop involving elevated intracellular calcium and enhanced mGluR1 function, a mechanism likely to contribute to Purkinje neuron dysfunction and loss in spinocerebellar ataxia type 2.

  7. mouse external globus pallidus astrocytes critically control ambient glutamate (zeige GRIN1 ELISA Kits) level, which in turn gates striatopallidal transmission via the activation of presynaptic metabotropic glutamate (zeige GRIN1 ELISA Kits) receptors.

  8. The results of our study showed that thalamic mGluR1-PLCbeta4 pathway was critical in controlling sleep architecture.

  9. This study confirmed the presence of mGluR1/5 complex by (i) reverse immunoprecipitation using an mGluR1 antibody to pulldown mGluR5 (zeige GRM5 ELISA Kits) from hippocampal tissue.

  10. results demonstrate that mGluR1 is crucial for the visual-experience-dependent maintenance of mature synaptic connectivity in the dorsal Lateral Geniculate Nuc.

Metabotropic Glutamate Receptor 1 (GRM1) Antigen-Profil

Beschreibung des Gens

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms\; some of which may have distinct functions.

Genbezeichner und Symbole assoziert mit GRM1

  • glutamate metabotropic receptor 1 (GRM1) Antikörper
  • glutamate receptor, metabotropic 1a (grm1a) Antikörper
  • metabotropic glutamate receptor 1 (mGlutR1) Antikörper
  • glutamate receptor, metabotropic 1 (Grm1) Antikörper
  • glutamate receptor, metabotropic 1 (GRM1) Antikörper
  • 4930455H15Rik Antikörper
  • ENSMUSG00000075319 Antikörper
  • fj39d05 Antikörper
  • GB18621 Antikörper
  • Glura Antikörper
  • Gm10828 Antikörper
  • Gprc1a Antikörper
  • MGLU1 Antikörper
  • mGluR1 Antikörper
  • mGlutR Antikörper
  • nmf373 Antikörper
  • rcw Antikörper
  • SCAR13 Antikörper
  • si:ch211-51a19.1 Antikörper
  • wobl Antikörper
  • wu:fj39d05 Antikörper

Bezeichner auf Proteinebene für GRM1

metabotropic glutamate receptor 1 , metabotropic glutamate receptor A , G protein coupled receptor, family C, group 1, member A , G protein-coupled receptor, family C, group 1, member A , G protein coupled receptor family C group 1 member A , mGluR1

GENE ID SPEZIES
100060603 Equus caballus
463049 Pan troglodytes
555576 Danio rerio
406151 Apis mellifera
2911 Homo sapiens
100625610 Sus scrofa
14816 Mus musculus
24414 Rattus norvegicus
421614 Gallus gallus
484024 Canis lupus familiaris
540485 Bos taurus
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