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GRINL1A encodes a subunit of RNA polymerase II, a protein complex that is responsible for synthesizing messenger RNA in eukaryotes. Zusätzlich bieten wir Ihnen Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate-Like 1A Antikörper (19) und Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate-Like 1A Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.
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The relatively slow functional loading of Gdown1 in the presence of TFIIF.
Data indicate that phosphorylation of Gdown1 on Ser-270 reduces Its affinity for RNA polymerase II.
Modification of TFIIF provides one pathway through which efficient Gdown1 loading can occur early in elongation, allowing downstream pausing to be regulated.
Gdown1 stabilizes poised polymerases while maintaining their responsiveness to P-TEFb.
Gdown1 competes with TFIIF for binding to the RPB1 and RPB5 subunits of Pol II, thereby inhibiting an essential function of TFIIF in preinitiation complex assembly.
Data identify GRINL1A as a membrane-associated DYNLL1 binding partner and suggest that additional DYNLL1-binding partners are present near this glutamate channel homolog.
This gene encodes a subunit of RNA polymerase II, a protein complex that is responsible for synthesizing messenger RNA in eukaryotes. The encoded protein functions as a component of a specific form of RNA polymerase II termed Pol II(G). This protein may act as a negative regulator of activator-dependent transcription. Alternate splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream gene MYZAP (myocardial zonula adherens protein).
DNA-directed RNA polymerase II subunit M, isoforms 4/5
, GRINL1A downstream protein Gdown4
, glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A
, protein GRINL1A
, protein GRINL1A, isoforms 4/5
, DNA-directed RNA polymerase II subunit GRINL1A
, DNA-directed RNA polymerase II subunit M
, glutamate receptor-like protein 1A
, GRINL1A downstream protein 1