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The protein encoded by GNPDA2 is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Zusätzlich bieten wir Ihnen Glucosamine-6-Phosphate Deaminase 2 Antikörper (41) und Glucosamine-6-Phosphate Deaminase 2 Kits (5) und viele weitere Produktgruppen zu diesem Protein an.
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GNPDA1 (zeige GNPDA1 Proteine) siRNA induced GFAT2 which was hardly measurable in these cells under standard culture conditions, GNPDA2 siRNA increased GFAT1 (zeige GFPT1 Proteine), and GFAT1 (zeige GFPT1 Proteine) siRNA increased the expression of hyaluronan synthase 2 (HAS2 (zeige HAS2 Proteine)). Silencing of GFAT1 (zeige GFPT1 Proteine) stimulated GNPDA1 (zeige GNPDA1 Proteine) and GDPDA2, and inhibited cell migration.
Data show that SNPs in SEC16B (zeige SEC16B Proteine) and TMEM18 (zeige TMM18 Proteine) were significantly associated with obesity, and the SNPs in GNPDA2, BDNF (zeige BDNF Proteine), FAIM2 (zeige FAIM2 Proteine) and MC4R (zeige MC4R Proteine) were marginally associated with obesity in Japanese.
The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
glcN6P deaminase 2
, glucosamine-6-phosphate isomerase 2
, glucosamine-6-phosphate isomerase SB52
, GNPDA 2