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binds vitamin B12 (cobalamin) [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen Intrinsic Factor Kits (39) und Intrinsic Factor Proteine (18) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal Intrinsic Factor Primary Antibody für WB - ABIN516030
Maloum, Allaire, Gagné-Sansfaçon, Roy, Belleville, Sarret, Morisset, Carrier, Mishina, Kaestner, Perreault: Epithelial BMP signaling is required for proper specification of epithelial cell lineages and gastric endocrine cells. in American journal of physiology. Gastrointestinal and liver physiology 2011
The gastric intrinsic factor (GIF) 290C heterozygous/fucosyltransferase 2 (secretor status included) protein (FUT2) rs601338 secretor variant combined genotype was indicated in 6 of the 37 neural tube defects (NTDs) fetuses.
the present findings reveal that High-altitude polycythemia -induced gastric mucosal lesion inspires the protection responses by up-regulating APOA4 and APOC3, and down-regulating GIF.
study reports that FUT2 secretor variant influences GIF secretion in B12 deficient cases bearing GIF heterozygous mutations, in absence of H. pylori related gastritis
Our genetic screening of 154 families of patients with inherited cobalamin malabsorption revealed population-specific mutations, mutational hotspots, and functionally distinct regions in the three causal genes: CUBN, AMN, and GIF.
Acute lymphoblastic leukemia and vitamin B12 deficiency secondary to a gastric intrinsic factor gene mutation
crystal structure of the complex between IF-Cbl and the cubilin IF-Cbl-binding-region (CUB(5-8)) determined at 3.3 A resolution
A polymorphism in the gastric intrinsic factor gene is associated with congenital intrinsic factor deficiency.
The parameters obtained for ligand and receptor binding in this study indicate that both full-length 50-kDA intrinsic factor and its 30-kDa and 20-kDa fragments may be involved in assimilation of cobalamin.
possible basis for the lack of interchangeability of human and rat IF receptors is presented
The Q5R mutation of the intrinsic factor gene predisposes to adult-onset pernicious anemia & other causes of low vitamin B12. In this mutation, intrinsic factor secretion is preserved but B12 absorption may be impaired.
a specific GIF mutation to be responsible for all Juvenile cobalamin deficiency cases of West-African origin so far was identified
Spasmolytic polypeptide/trefoil factor family 2 (TFF2)-expressing metaplasia (SPEM)was immunoreactive for TFF2, Mist1 and intrinsic factor, suggesting that SPEM derived from transdifferentiation of chief cells.
binds vitamin B12 (cobalamin)
gastric intrinsic factor (vitamin B synthesis)
, gastric intrinsic factor
, intrinsic factor
, pancreatic intrinsic factor
, gastric intrinsic factor-like