anti-Gasdermin D (GSDMD) Antikörper

Gasdermin D is a member of the gasdermin family. Zusätzlich bieten wir Ihnen Gasdermin D Kits (13) und Gasdermin D Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GSDMD 79792 P57764
GSDMD 69146 Q9D8T2
GSDMD 315084  
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Top anti-Gasdermin D Antikörper auf antikoerper-online.de

Showing 10 out of 34 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: GSDMDC1 Antibody [NBP2-33422] - Ovarian cancer Immunohistochemistry-Paraffin: GSDMDC1 Antibody [NBP2-33422] - Liver 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert WB Western Blot: GSDMDC1 Antibody [NBP2-14974] - Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE, antibody diluted at 1:500. Western Blot: GSDMDC1 Antibody  - Whole cell extract (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with GSDMD antibody diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Human Maus Unkonjugiert EIA, IF, IHC (p), WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$445.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of mouse lung and rat liver cell lines, using GSDMD antibody. 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Maus Unkonjugiert IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to GSDMDC1 on formalin-fixed paraffin-embedded human tonsil tissue. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to GSDMDC1 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert ELISA, IF, IHC, WB Immunofluorescence of monoclonal antibody to GSDMDC1 on HeLa cell (antibody concentration 10 µg/mL). GSDMDC1 monoclonal antibody (M01), clone 3F12-1B2 Western Blot analysis of GSDMDC1 expression in Jurkat. 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$461.00
Details
Human Maus Unkonjugiert ELISA, IF, IHC, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$550.00
Details
Human Maus Unkonjugiert ELISA, IF, IHC (p), WB Immunohistochemistry-Paraffin: GSDMDC1 Antibody (3F12-1B2) [NBP1-69898] - Analysis of anti-GSDMD / DFNA5L antibody with human small intestine at concentration 5 ug/ml. 0.05 mg Anmelden zum Anzeigen 34 Days
$585.06
Details
Human Kaninchen Unkonjugiert WB Western Blot analysis of GSDMD expression in transfected 293T cell line by GSDMD MaxPab polyclonal antibody.<br><br>Lane 1: GSDMDC1 transfected lysate(52.80 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$425.71
Details
Human Maus Unkonjugiert WB Western Blot analysis of GSDMD expression in transfected 293T cell line by GSDMD MaxPab polyclonal antibody.<br><br>Lane1:GSDMDC1 transfected lysate(53.24 KDa).<br>Lane2:Non-transfected lysate.<br> 50 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details

GSDMD Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,
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Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-Gasdermin D Antikörper

  1. Human Polyclonal GSDMD Primary Antibody für ICC, IF - ABIN4316340 : Liu, Zhang, Ruan, Pan, Magupalli, Wu, Lieberman: Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. in Nature 2016 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen Gasdermin D Interaktionspartner

Human Gasdermin D (GSDMD) Interaktionspartner

  1. These findings reveal that GSDMD-C acts as an auto-inhibition executor and GSDMD-N could form pore structures via a charge-charge interaction upon cleavage by caspases during cell pyroptosis.

  2. This study reveals the pore-forming activity of GSDMD and channel-forming activity of MLKL determine different ways of plasma membrane rupture in pyroptosis and necroptosis.

  3. GsdmD p30 (zeige CENPV Antikörper) kills cells by forming pores that compromise the integrity of the cell membrane.

  4. Data, including data from studies using recombinant fusion forms of GSDMD, suggest that GSDMD participates in inflammasome-dependent pyroptosis of macrophages in response to various stimuli; this mechanism involves proteolysis of GSDMD by caspase-1 (zeige CASP1 Antikörper) and caspase-11 (zeige CASP4 Antikörper).

  5. Remarkably, the Enterovirus 71 protease 3C directly targets GSDMD and induces its cleavage, which is dependent on the protease activity.

  6. The pyroptosis is redefined as gasdermin D-mediated programmed necrosis. Gasdermin D are associated with various genetic diseases, and their cellular function and mechanism of activation.

  7. Overall, these data demonstrate that GSDMD is the direct and final executor of pyroptotic cell death.

  8. Studies show that the membrane-pores composed of gasdermin D-N domains (GSDMD-N domain) are required for pyroptosis.

  9. Studies indicate that gasdermin D (GSDMD) is cleaved by the activated caspases-1/4/5/11 between its N-terminal and C-terminal domains.

  10. Gene deletion of GSDMD demonstrated that GSDMD is required for pyroptosis and for the secretion but not proteolytic maturation of IL-1beta (zeige IL1B Antikörper) in both canonical and non-canonical inflammasome responses.

Mouse (Murine) Gasdermin D (GSDMD) Interaktionspartner

  1. This study reveals the pore-forming activity of GSDMD and channel-forming activity of MLKL determine different ways of plasma membrane rupture in pyroptosis and necroptosis.

  2. Gene deletion of GSDMD demonstrated that GSDMD is required for pyroptosis and for the secretion but not proteolytic maturation of IL-1beta (zeige IL1B Antikörper) in both canonical and non-canonical inflammasome responses.

  3. identification of gasdermin D (Gsdmd) by genome-wide clustered regularly interspaced palindromic repeat (CRISPR)-Cas9 nuclease (zeige DCLRE1C Antikörper) screens of caspase-11 (zeige CASP4 Antikörper)- and caspase-1 (zeige CASP1 Antikörper)-mediated pyroptosis in mouse bone marrow macrophages

  4. gasdermin D is essential for caspase-11-dependent pyroptosis and interleukin-1beta maturation

  5. This study clearly shows that Gsdmd is not essential for development of mouse intestinal tract or epithelial cell differentiation.

Gasdermin D (GSDMD) Antigen-Profil

Protein Überblick

Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.

Genbezeichner und Symbole assoziert mit anti-Gasdermin D (GSDMD) Antikörper

  • gasdermin D (GSDMD) Antikörper
  • gasdermin D (Gsdmd) Antikörper
  • 1810036L03Rik Antikörper
  • AW558049 Antikörper
  • DF5L Antikörper
  • Dfna5l Antikörper
  • GSDMD Antikörper
  • Gsdmdc1 Antikörper
  • M2-4 Antikörper

Bezeichner auf Proteinebene für anti-Gasdermin D (GSDMD) Antikörper

gasdermin domain containing 1 , gasdermin-D , gasdermin D , gasdermin domain-containing protein 1

GENE ID SPEZIES
513939 Bos taurus
609395 Canis lupus familiaris
697137 Macaca mulatta
739712 Pan troglodytes
100604427 Nomascus leucogenys
79792 Homo sapiens
69146 Mus musculus
315084 Rattus norvegicus
Ausgewählte Anbieter für anti-Gasdermin D (GSDMD) Antikörper
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