anti-Galactosidase, alpha (GLA) Antikörper

GLA encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. Zusätzlich bieten wir Ihnen GLA Kits (38) und GLA Proteine (18) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GLA 2717 P06280
GLA 11605  
GLA 363494  
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Top anti-GLA Antikörper auf antikoerper-online.de

Showing 10 out of 127 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-GLA Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Human brain 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB GLA Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GLA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of GLA antibody (N-term) in Hela cell line lysates (35 µg/lane). GLA (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Maus Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert IP, IHC (p), WB WB Image Galactosidase alpha antibody [N1C2] detects Galactosidase alpha protein by western blot analysis. Rat tissue extracts (50 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with Galactosidase alpha antibody [N1C2] , diluted at 1:1000. WB Image Galactosidase alpha antibody detects Galactosidase alpha protein by western blot analysis. Whole cell extracts (30 μg) was separated by 10% SDS-PAGE, and the membrane was blotted with Galactosidase alpha antibody , at a dilution of 1:1000. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Western blot analysis of GLA antibody (N-term) (ABIN390687) in Hela cell line lysates (35 µg/lane). GLA (arrow) was detected using the purified polyclonal antibody. GLA Antibody (N-term) (ABIN390687) IHC analysis in formalin fixed and paraffin embedded human Lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human rectal carcinoma labeled with Anti-Galactosidase alpha Polyclonal Antibody, Unconjugated (ABIN872875) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Lane 1: mouse liver lysates Lane 2: human colon carcinoma lysates probed with Anti Galactosidase alpha Polyclonal Antibody, Unconjugated (ABIN872875) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 44kD. Observed band size: 44kD. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry-Paraffin: Galactosidase alpha Antibody [NBP1-89796] - Staining of human small intestine shows strong cytoplasmic positivity in glandular cells. Western Blot: alpha-Galactosidase A/GLA Antibody [NBP1-89796] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11 Lane 2: Human cell line RT-4 Lane 3: Human cell line U-251MG sp Lane 4: Human plasma (IgG/HSA depleted) Lane 5: Human liver tissue 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Alexa Fluor 350 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen HRP IHC (p), WB   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

GLA Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GLA Antikörper

  1. Human Polyclonal GLA Primary Antibody für IHC, IHC (p) - ABIN4280010 : Xu, Lun, Brignol, Hamler, Schilling, Frascella, Sullivan, Boyd, Chang, Soska, Garcia, Feng, Yasukawa, Shardlow, Churchill, Ketkar, Robertson, Miyamoto, Mihara, Benjamin, Lockhart, Hirato, Fowles et al.: Coformulation of a Novel Human α-Galactosidase A With the Pharmacological Chaperone AT1001 Leads to Improved Substrate Reduction in Fabry Mice. ... in Molecular therapy : the journal of the American Society of Gene Therapy 2015 (PubMed)

Weitere Antikörper gegen GLA Interaktionspartner

Human Galactosidase, alpha (GLA) Interaktionspartner

  1. Results showed that most Fabry disease patients carrying GLA (zeige NAT8 Antikörper) IVS4+919A did not show abnormal cardiac phenotypes. The near-absence of GLA (zeige NAT8 Antikörper) IVS4+919A in heart disease cohort suggested that this variant is not a frequent cause of overt heart diseases in Taiwan.

  2. Enzyme activities (acid alpha-glucosidase (GAA), galactocerebrosidase (GALC (zeige GALC Antikörper)), glucocerebrosidase (GBA (zeige GBA Antikörper)), alpha-galactosidase A (GLA), alpha-iduronidase (IDUA (zeige IDUA Antikörper)) and sphingomyeline phosphodiesterase-1 (SMPD-1 (zeige SMPD1 Antikörper))) were measured on ~43,000 de-identified dried blood spot (DBS (zeige MCF2L Antikörper)) punches, and screen positive samples were submitted for DNA sequencing to obtain genotype confirmation of disease risk

  3. This longitudinal Fabry Registry study analyzed data from patients with Fabry disease to determine the incidence and type of severe clinical events following initiation of enzyme replacement therapy (ERT (zeige ELF3 Antikörper)) with agalsidase beta, as well as risk factors associated with occurrence of these events

  4. alpha-galactosidase A mutation, IVS4-type Fabry disease has features similar to those of classic Fabry disease and a higher frequency of deep white matter hyperintensities and a higher incidence of infarctions and pulvinar signs than in healthy controls

  5. We demonstrate that the wild-type sequence harbors an hnRNP A1 (zeige HNRNPA1 Antikörper) and hnRNP A2/B1 (zeige HNRNPA2B1 Antikörper)-binding exonic splicing silencer (ESS) overlapping the 5'splice site (5'ss) that prevents pseudoexon inclusion.we demonstrate that splice switching oligonucleotide (SSO) mediated blocking of the pseudoexon 3'ss and 5'ss effectively restores normal GLA (zeige NAT8 Antikörper) splicing

  6. Four patients had non-amenable mutant forms of a-Gal (zeige GAL Antikörper) based on the validated cell-based assay conducted after treatment initiation and were excluded from primary efficacy analyses only.

  7. Mesenchymal stem cells with reduced GLA (zeige NAT8 Antikörper) activity are prone to apoptosis and senescence due to impaired autophagy and DNA repair capacity.

  8. we review the various types of GLA (zeige NAT8 Antikörper) variants and recommend that pathogenicity be considered only when associated with elevated globotriaosylceramide in disease-relevant organs and tissues as analyzed by mass spectrometry.

  9. findings revealed the alternative splicing mechanism of GLA (zeige NAT8 Antikörper) (IVS4+919G>A), and a potential treatment for this specific genetic type of Fabry disease by amiloride in the future

  10. Results found a novel heterozygous stop codon mutation in exon 1 of the GLA (zeige NAT8 Antikörper) gene in female patients with Fabry Disease with methylation in the non-mutated allele thought to be associated with the clinical severity of the disease.

Mouse (Murine) Galactosidase, alpha (GLA) Interaktionspartner

  1. Therefore, we confirmed the associations among Golgi function, fibrosis, and autophagy. Moreover, GOLGA2 (zeige GOLGA2 Antikörper) knockout mice may be a potentially valuable animal model for studying autophagy-induced fibrosis.

  2. the GM130 (zeige GOLGA2 Antikörper)-deficient mouse provides a valuable model for investigating the etiology of human globozoospermia.

  3. Mice with alpha-galactosidase A deficiency show age-dependent and distinct deficits of the sensory system.

  4. In oocyte meiosis, GM130 (zeige GOLGA2 Antikörper) localization and expression patterns are regulated by FMNL1 (zeige FMNL1 Antikörper).

  5. The histological changes in Gla KO mice better resemble the type 2 later-onset phenotype observed in patients with residual alpha-galactosidase A activity.

  6. our findings imply that the alpha-GalA KO mouse is a good model in which to study the peripheral small fiber neuropathy exhibited by FD patients

  7. we demonstrate an age-dependent microvasculopathy of the mesenteric artery in a murine model of Fabry disease (galactosidase A-knockout mice) resulting from dysregulation of the vascular homeostatic enzyme endothelial nitric oxide synthase (eNOS (zeige NOS3 Antikörper))

  8. GM130 (zeige GOLGA2 Antikörper) regulates microtubule organization and might cooperate with the MAPK (zeige MAPK1 Antikörper) pathway to play roles in spindle organization, migration and asymmetric division during mouse oocyte maturation

  9. It suggested that there could be a combination of GLA deficiency and FVL (zeige F5 Antikörper) or other thrombosis-related gene defect in patients with genetic severe early-onset thrombosis.

  10. present Toll (zeige TLR4 Antikörper)-like receptor-dependent negative regulation of alpha-Gal-A as a mechanistic link between pathogen recognition and self lipid antigen induction for natural killer T cells

GLA Antigen-Profil

Protein Überblick

This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

Genbezeichner und Symbole assoziert mit GLA

  • galactosidase alpha (GLA) Antikörper
  • galactosidase, alpha (Gla) Antikörper
  • galactosidase, alpha (gla) Antikörper
  • galactosidase alpha S homeolog (gla.S) Antikörper
  • galactosidase alpha (gla) Antikörper
  • alpha-galactosidase (agaN) Antikörper
  • aga (aga) Antikörper
  • alpha-galactosidase (agaL) Antikörper
  • alpha-galactosidase (SCO0541) Antikörper
  • alpha-galactosidase (rafA) Antikörper
  • alpha-galactosidase (melA) Antikörper
  • alpha-galactosidase (galA) Antikörper
  • alpha-galactosidase A (ANI_1_2528074) Antikörper
  • alpha-galactosidase A (ANI_1_1502124) Antikörper
  • alpha-galactosidase A (AOR_1_390174) Antikörper
  • alpha-galactosidase A (CpipJ_CPIJ002066) Antikörper
  • alpha-galactosidase (aga) Antikörper
  • alpha-galactosidase A (MCYG_00962) Antikörper
  • alpha-galactosidase A (MCYG_00791) Antikörper
  • alpha-galactosidase (gla) Antikörper
  • alpha-galactosidase A (Tsp_02909) Antikörper
  • alpha-galactosidase A (Tsp_02508) Antikörper
  • golgi autoantigen, golgin subfamily a, 2 (Golga2) Antikörper
  • galactosidase alpha (Gla) Antikörper
  • galactosidase, alpha (GLA) Antikörper
  • Ags Antikörper
  • alpha-GAL Antikörper
  • AO090005000217 Antikörper
  • AW555139 Antikörper
  • GALA Antikörper
  • GM130 Antikörper
  • MGC130872 Antikörper
  • mKIAA4150 Antikörper
  • SCF11.21 Antikörper
  • SMU.877 Antikörper
  • zgc:101584 Antikörper

Bezeichner auf Proteinebene für GLA

agalsidase alfa , alpha-D-galactosidase A , alpha-D-galactoside galactohydrolase 1 , alpha-gal A , alpha-galactosidase A , melibiase , alpha-D-galactoside galactohydrolase , Alpha-galactosidase A , galactosidase, alpha , alpha-galactosidase A-like , alpha-galactosidase , Alpha-galactosidase , 130 kDa cis-Golgi matrix protein , Golgin subfamily A member 2 , SY11 protein , golgin-95

GENE ID SPEZIES
2717 Homo sapiens
11605 Mus musculus
363494 Rattus norvegicus
422188 Gallus gallus
450083 Danio rerio
465761 Pan troglodytes
480988 Canis lupus familiaris
532742 Bos taurus
703129 Macaca mulatta
734749 Xenopus laevis
100022779 Monodelphis domestica
100060370 Equus caballus
100145767 Xenopus (Silurana) tropicalis
100344610 Oryctolagus cuniculus
100409841 Callithrix jacchus
100480888 Ailuropoda melanoleuca
100595113 Nomascus leucogenys
988766 Clostridium perfringens str. 13
1021683 Bifidobacterium longum NCC2705
1028243 Streptococcus mutans UA159
1095964 Streptomyces coelicolor A3(2)
1174420 Yersinia pestis CO92
1255824 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
2956399 Yersinia pseudotuberculosis IP 32953
3977399 Lactobacillus salivarius UCC118
4983447 Aspergillus niger CBS 513.88
4987403 Aspergillus niger CBS 513.88
5989256 Aspergillus oryzae RIB40
6032795 Culex quinquefasciatus
7264928 Bifidobacterium animalis subsp. lactis AD011
9223595 Arthroderma otae CBS 113480
9226616 Arthroderma otae CBS 113480
9450395 Brachyspira pilosicoli 95/1000
10899858 Trichinella spiralis
10903123 Trichinella spiralis
99412 Mus musculus
100718405 Cavia porcellus
407057 Sus scrofa
Ausgewählte Anbieter für anti-GLA (GLA) Antikörper
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