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GIMAP6 encodes a member of the GTPases of immunity-associated proteins (GIMAP) family. Zusätzlich bieten wir Ihnen GIMAP6 Antikörper (24) und viele weitere Produktgruppen zu diesem Protein an.
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GIMAP6 plays a role in modulating immune function and that it does this by controlling cell death and the activation of T cells.
These data,demonstrating the downregulation of the mRNA and protein expression levels of GIMAP5 (zeige GIMAP5 Proteine) and GIMAP6 in the tumor tissues and blood of patients with Hepatocellular carcinoma (HCC (zeige FAM126A Proteine)) , suggested the involvement of GIMAP5 (zeige GIMAP5 Proteine) and GIMAP6 in the pathogenesis of HCC (zeige FAM126A Proteine), and indicate their possible use as diagnostic markers for HCC (zeige FAM126A Proteine).
The results indicate a requirement for GIMAP6 in the maintenance of a normal peripheral adaptive immune system and a significant role for the protein in normal autophagic processes. Moreover, as GIMAP6 is expressed in a cell-selective manner, this indicates the potential existence of a cell-restricted mode of autophagic regulation.
This gene encodes a member of the GTPases of immunity-associated proteins (GIMAP) family. GIMAP proteins contain GTP-binding and coiled-coil motifs, and may play roles in the regulation of cell survival. Decreased expression of this gene may play a role in non-small cell lung cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is found in a cluster with seven additional GIMAP genes on the long arm of chromosome 7.
GTPase, IMAP family member 6
, GTPase IMAP family member 6
, immune associated nucleotide 2
, immune associated nucleotide 6
, immune-associated nucleotide 6
, immunity-associated nucleotide 6 protein