anti-GRB2-Related Adaptor Protein (GRAP) Antikörper

GRAP encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. Zusätzlich bieten wir Ihnen GRAP Proteine (5) und GRAP Kits (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GRAP 10750 Q13588
GRAP 71520 Q9CX99
GRAP 363616  
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Top anti-GRAP Antikörper auf

Showing 10 out of 59 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-GRAP Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: THP-1 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: Grap Antibody Dilution: 1.0ug/ml Sample Type: Rat Spleen 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Ziege Unkonjugiert ELISA, WB ABIN184595 (0.3µg/ml) staining of human thymus lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from 293/MCF-7/COLO cells, using GRAP Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Rind (Kuh) Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB ICC/IF Image Immunofluorescence analysis of methanol-fixed A549, using GRAP, antibody at 1:500 dilution. IHC-P Image Immunohistochemical analysis of paraffin-embedded U373 xenograft, using GRAP, antibody at 1:100 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
Hamster Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: GRAP Antibody [NBP2-16737] - Sample (30 ug of whole cell lysate) A: MCF-7 12% SDS PAGE gel, diluted at 1:2000. Immunohistochemistry-Paraffin: GRAP Antibody [NBP2-16737] - Immunohistochemical analysis of paraffin-embedded Hepatoma, using antibody at 1:500 dilution. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage

GRAP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GRAP Antikörper

  1. Human Polyclonal GRAP Primary Antibody für ELISA, WB - ABIN256861 : Fathi, Rasouli, Yeganeh, Salekdeh, Baharvand: Efficient differentiation of human embryonic stem cells toward dopaminergic neurons using recombinant LMX1A factor. in Molecular biotechnology 2015 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen GRAP Interaktionspartner

Human GRB2-Related Adaptor Protein (GRAP) Interaktionspartner

  1. A compound mutation consisting of a large deletion and a nonsense mutation, which provides a new insight in the mutation type of CTSC (zeige CTSC Antikörper) gene.

  2. CTSC (zeige CTSC Antikörper) gene missense mutation is responsible for Papillo- Lefevre syndrome in a Turkish family.

  3. analysis of fluorescent substrates provides a detailed S' specificity study of cathepsin C (zeige CTSC Antikörper)

  4. Mutation screening of the CTSC (zeige CTSC Antikörper) gene from the two patients revealed the presence of the same homozygous nonsense mutation in Papillon-Lefevre syndrome and Haim-Munk syndromes. Phenotypic variants of the same rare disease caused by mutations of the cathepsin C (CTSC (zeige CTSC Antikörper)) gene.

  5. Neutrophilic Cathepsin C (zeige CTSC Antikörper) Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.

  6. CTSC (zeige CTSC Antikörper) was associated with albuminuria in type 2 diabetes patients.

  7. Homozygous mutation 901G>A in exon 7 of CTSC (zeige CTSC Antikörper) gene is associated with Papillon-Lefevre syndrome.

  8. Results identify a missense mutation in CTSC (zeige CTSC Antikörper) gene that segregate within a family with Papillon-Lefevre syndrome.

  9. Papillon-Lefevre syndrome cause by homozygous nonsense mutation of cathepsin C (zeige CTSC Antikörper) gene.

  10. CatC (zeige CTSC Antikörper) has a role in the selective tuning of innate and adaptive immune responses, relevant to a chronic immune disease, such as atherosclerosis.

Mouse (Murine) GRB2-Related Adaptor Protein (GRAP) Interaktionspartner

  1. Grb2-related adaptor protein (GRAP) was up-regulated in kidney tubules from diabetic mice, indicating a potential novel role for GRAP in TGF-beta (zeige TGFB1 Antikörper)-induced tubule injury in diabetic kidney disease.

  2. Data suggest that Grap, unlike Grb2 (zeige GRB2 Antikörper), acts as a negative regulator of TCR-stimulated intracellular signaling by downregulating signal relay through the Ras/Erk (zeige EPHB2 Antikörper) pathway.

  3. Results suggest that the GRAP gene might have a role in the pathogenesis of Sjogren's syndrome.

  4. FcgammaRIIB docking site for the SH2 (zeige MYO15 Antikörper) domain-containing adapters Grb2 (zeige GRB2 Antikörper) and Grap

GRAP Antigen-Profil

Protein Überblick

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit GRAP

  • GRB2-related adaptor protein (GRAP) Antikörper
  • cathepsin C (CTSC) Antikörper
  • GRB2-related adaptor protein (Grap) Antikörper
  • GRB2-related adapter protein (LOC489534) Antikörper
  • GRB2-related adaptor protein a (grapa) Antikörper
  • GRB2-related adaptor protein b (grapb) Antikörper
  • GRB2-related adapter protein (LOC100727005) Antikörper
  • 8430435N19Rik Antikörper
  • BB233594 Antikörper
  • CPPI Antikörper
  • DPP-I Antikörper
  • DPP1 Antikörper
  • DPPI Antikörper
  • Grap Antikörper
  • HMS Antikörper
  • JP Antikörper
  • JPD Antikörper
  • MGC109892 Antikörper
  • PALS Antikörper
  • PDON1 Antikörper
  • PLS Antikörper
  • si:dkeyp-9d4.1 Antikörper
  • zgc:110202 Antikörper

Bezeichner auf Proteinebene für GRAP

GRB2-related adapter protein , growth factor receptor-bound protein 2-related adaptor protein , cathepsin J , dipeptidyl peptidase 1 , dipeptidyl peptidase I , dipeptidyl transferase , dipeptidyl-peptidase I , GRB2-related adaptor protein

10750 Homo sapiens
1075 Homo sapiens
71520 Mus musculus
363616 Rattus norvegicus
416523 Gallus gallus
489534 Canis lupus familiaris
534491 Bos taurus
553596 Danio rerio
555184 Danio rerio
100727005 Cavia porcellus
Ausgewählte Anbieter für anti-GRAP (GRAP) Antikörper
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