GM2 Ganglioside Activator Proteine (GM2A)

GM2A encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Zusätzlich bieten wir Ihnen GM2 Ganglioside Activator Antikörper (155) und GM2 Ganglioside Activator Kits (19) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte GM2A GM2A 282838  
GM2A 2760 P17900
GM2A 14667 Q60648
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Top GM2 Ganglioside Activator Proteine auf antikoerper-online.de

Showing 10 out of 16 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
Baculovirus infected Insect Cells Human His tag 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
$250.80
Details
Escherichia coli (E. coli) Human GST tag GM2 Ganglioside Activator (GM2A) (AA 32-193), (full length) protein (GST tag) 1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$1,842.50
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details
Hefe Cynomolgus His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,383.33
Details
Human Human His tag 50 μg Anmelden zum Anzeigen 6 bis 9 Tage
$390.05
Details
Escherichia coli (E. coli) Human GST tag   100 μg Anmelden zum Anzeigen 11 Days
$411.40
Details
Human Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$300.00
Details

GM2A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , ,
, , ,
Mouse (Murine)

Weitere Proteine zu GM2 Ganglioside Activator (GM2A) Interaktionspartnern

Human GM2 Ganglioside Activator (GM2A) Interaktionspartner

  1. Review of GM2A mutations causing GM2 (zeige CYB5D2 Proteine) activator protein deficiency and GM2 (zeige CYB5D2 Proteine) gangliosidosis-AB variant.

  2. Studies indicate that sphingolipid activator proteins (SAPs (zeige SKAP2 Proteine)) and anionic lipids are essential stimulators to reach physiological rates of lysosomal sphingolipid degradation.

  3. this study has established the potential role of GM2A in breast cancer progression

  4. Mobilization of membrane lipids by GM2AP was also inhibited in the presence of cholesterol or SM, as revealed by surface plasmon resonance studies

  5. Gene polymorphisms of MD2 (zeige LY96 Proteine) and GM2A were associated with the occurrence or severity of neonatal necrotizing enterocolitis.

  6. In vitro assays with the isolated H1 or H2 homodimers (beta-alpha hybrid construct of beta-hexosaminidase A subunits) confirmed that neither was capable of human GM2AP-dependent hydrolysis of GM2 (zeige CYB5D2 Proteine) ganglioside.

  7. impact of GM2AP on glucose metabolism

  8. Treatment of meniscal explants with IL-1RA (zeige IL1RN Proteine) inhibited the expression of many catabolic genes following a single bout of high dynamic strain.

  9. these results provide novel insights into the physiological functions of GM2AP in obesity.

  10. GM2 (zeige CYB5D2 Proteine) activator protein exerts strong and broad inhibitory effects on the hydrolysis of phospholipids carried out by plant and microbial phospholipases D

Mouse (Murine) GM2 Ganglioside Activator (GM2A) Interaktionspartner

  1. The most interesting finding was the association of the GM2-AP with the acrosomal apparatus in early spermatids. A modest to intense staining was observed in some acrosomal granules and acrosomal caps (zeige CAPS Proteine). The GM2-AP seemed to disappear from acrosomal caps (zeige CAPS Proteine) in the later stage of spermatids, in which the nucleus became elongated and condensed.

  2. impact of GM2AP on glucose metabolism

  3. these results provide novel insights into the physiological functions of GM2AP in obesity.

  4. GM2 (zeige CYB5D2 Proteine) activator protein exerts strong and broad inhibitory effects on the hydrolysis of phospholipids carried out by plant and microbial phospholipases D

  5. The trafficking of prosaposin (zeige PSAP Proteine) and GM2 (zeige CYB5D2 Proteine) activator protein to the lysosome in sertoli cells is dependent on sortilin (zeige SORT1 Proteine).

GM2 Ganglioside Activator (GM2A) Protein Überblick

Protein Überblick

This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit GM2A

  • GM2 ganglioside activator (Gm2a)
  • GM2 ganglioside activator (GM2A)
  • GM2 ganglioside activator (gm2a)
  • GM2 ganglioside activator L homeolog (gm2a.L)
  • GM2 ganglioside activator protein (Gm2a)
  • AA408702 Protein
  • AW215435 Protein
  • fb96e04 Protein
  • fb96e10 Protein
  • GM2-AP Protein
  • GM2A Protein
  • MGC84154 Protein
  • SAP-3 Protein
  • wu:fb96e04 Protein
  • wu:fb96e10 Protein
  • zgc:110188 Protein

Bezeichner auf Proteinebene für GM2A

GM2 ganglioside activator protein , ganglioside GM2 activator , GM2 ganglioside activator , GM2 activator protein , cerebroside sulfate activator protein , shingolipid activator protein 3 , sphingolipid activator protein 3

GENE ID SPEZIES
282838 Rattus norvegicus
471705 Pan troglodytes
479324 Canis lupus familiaris
504524 Bos taurus
548463 Xenopus (Silurana) tropicalis
550529 Danio rerio
779153 Xenopus laevis
100174922 Felis catus
2760 Homo sapiens
14667 Mus musculus
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