GDP-Mannose 4,6-Dehydratase (GMDS) ELISA Kits

GDP-mannose 4,6-dehydratase (GMD\\\\; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. Zusätzlich bieten wir Ihnen GDP-Mannose 4,6-Dehydratase Antikörper (51) und GDP-Mannose 4,6-Dehydratase Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
GMDS 218138 Q8K0C9
Anti-Ratte GMDS GMDS 291095  
GMDS 2762 O60547
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Top GDP-Mannose 4,6-Dehydratase ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Lieferzeit Preis Details
Human < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 bis 18 Tage
$838.60
Details
Maus < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests 11 bis 18 Tage
$838.60
Details

Weitere ELISA Kits für GDP-Mannose 4,6-Dehydratase Interaktionspartner

Human GDP-Mannose 4,6-Dehydratase (GMDS) Interaktionspartner

  1. Study findings suggest that GMDS upregulation is critical for cell proliferation and survival in human lung adenocarcinoma and might serve as a potential biomarker for lung adenocarcinoma diagnosis and treatment.

  2. Disruptions of enhancers near FOXC1 and GMDS may influence brain development.

  3. Data indicate three loci associated with primary open-angle glaucoma (POAG) were located upstream of ATP binding cassette transporter 1 (ABCA1), within actin filament associated protein 1 (AFAP1) and within GDP-mannose 46-dehydratase (GMDS).

  4. These data demonstrate involvement of GMDS mutation in the progression of colorectal cancer.

  5. Fx enzyme and GDP-L-Fuc Tr overexpression in the tumur tissue of colorectal cancer (CRC) patients suggests that GDP-L-Fuc transport to the Golgi apparatus may be an important factor associated with increased alpha(1,6)fucosylation in CRC.

  6. GMD inhibits tankyrase 1 poly(ADP-ribose) polymerase activity in vitro, dependent on the GMD tankyrase 1 binding motif. In vivo, depletion of GMD led to degradation of tankyrase 1, dependent on the catalytic PARP activity of tankyrase 1.

  7. Results indicate that GMDS regulates the formation of secondary complex II from the primary DISC independent of direct fucosylation of death receptors.

  8. FX takes part in the cascade of events leading to the extravasation of activated lymphocytes.

  9. Deficiency of GMDS leads to escape from natural killer cell-mediated tumor surveillance through modulation of TRAIL signaling.

GDP-Mannose 4,6-Dehydratase (GMDS) Antigen-Profil

Beschreibung des Gens

GDP-mannose 4,6-dehydratase (GMD\; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).

Genbezeichner und Symbole assoziert mit GMDS

  • GDP-mannose 4, 6-dehydratase (Gmds) Antikörper
  • GDP-mannose 4,6-dehydratase (GMDS) Antikörper
  • BC031788 Antikörper
  • C87208 Antikörper
  • GMD Antikörper
  • SDR3E1 Antikörper

Bezeichner auf Proteinebene für GMDS

GDP-D-mannose dehydratase , GDP-mannose 4,6 dehydratase , GMD , short chain dehydrogenase/reductase family 3E, member 1

GENE ID SPEZIES
218138 Mus musculus
291095 Rattus norvegicus
2762 Homo sapiens
420890 Gallus gallus
488189 Canis lupus familiaris
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