GDNF Family Receptor alpha 2 (GFRA2) ELISA Kits

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. Zusätzlich bieten wir Ihnen GFRA2 Antikörper (82) und GFRA2 Proteine (17) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
GFRA2 2675 O00451
Anti-Maus GFRA2 GFRA2 14586  
Anti-Ratte GFRA2 GFRA2 25136  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human
  96 Tests Anmelden zum Anzeigen 31 bis 41 Tage
$734.80
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Weitere ELISA Kits für GFRA2 Interaktionspartner

Human GDNF Family Receptor alpha 2 (GFRA2) Interaktionspartner

  1. The cardiac GFRA2 signaling pathway is distinct from the canonical pathway dependent on the RET (zeige RET ELISA Kits) tyrosine kinase (zeige TXK ELISA Kits).

  2. High GFRalpha2 expression level leads to PTEN inactivation via Mir-17-5p up-regulation, promoting pancreatic tumor cell growth and chemoresistance.

  3. GFRA2 variants associated with diabetic neuropathic pain.

  4. The study shows co-localization of RET (zeige RET ELISA Kits) with GFRA1 (zeige GFRA1 ELISA Kits) and GFRA2 in myenteric ganglia of the adult human colon.

  5. Cyclic AMP (zeige APRT ELISA Kits) signalling through PKA but not Epac is essential for neurturin (zeige NRTN ELISA Kits)-induced biphasic ERK1/2 (zeige MAPK1/3 ELISA Kits) activation and neurite outgrowths through GFRalpha2 isoforms.

  6. GFRA2 genetic variants, and age, may play a role in susceptibility to tardive dyskinesia.

  7. This study found nominally-significant evidence for interactions between GFRA1 (zeige GFRA1 ELISA Kits), 2 and 3 associated with schizophrenia and clozapine response, consistent with the locations of these three genes within linkage regions for schizophrenia.

  8. Both GFR alpha2a and GFR alpha2c, but not GFR alpha2b, promote neurite outgrowth in transfected Neuro2A cells.

Mouse (Murine) GDNF Family Receptor alpha 2 (GFRA2) Interaktionspartner

  1. The cardiac GFRA2 signaling pathway is distinct from the canonical pathway dependent on the RET (zeige RET ELISA Kits) tyrosine kinase (zeige TYRO3 ELISA Kits).

  2. Ret (zeige RET ELISA Kits) and Gfra2 null mice display comparable early central projection deficits, but Gfra2 null rapidly adapting mechanoreceptors recover later.

  3. STAT3 (zeige STAT3 ELISA Kits) phosphorylation by neurturin (zeige NRTN ELISA Kits) was found to be mediated specifically by GFRalpha2c and RET9 (zeige RET ELISA Kits) isoforms.

  4. Cholinergic innervation of gastric mucosa depends on neurturin (zeige NRTN ELISA Kits)-GFRalpha2 signalling but is dispensable for gastrin (zeige GAST ELISA Kits) secretion and for basal and maximal acid output

  5. our data demonstrate that RET (zeige RET ELISA Kits)/GFRalpha signals are dispensable for thymic T cell development in vivo

  6. Transduction-function role for GFR alpha2/neurturin (zeige NRTN ELISA Kits) signalling in a specific class of sensory neurons.

  7. The cholinergic subpopulation of sympathetic neurons requires GFR alpha 2 signaling for soma size and for growth or maintenance of target innervation.

  8. Demonstrate a role for GFRalpha2-expressing enteric neurons in the downstream signaling of the glucagon (zeige GCG ELISA Kits)-like peptides to inhibit GI motility, but not in intestinal growth.

GFRA2 Antigen-Profil

Beschreibung des Gens

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit GFRA2

  • GDNF family receptor alpha 2 (GFRA2) Antikörper
  • glial cell line derived neurotrophic factor family receptor alpha 2 (Gfra2) Antikörper
  • GDNF family receptor alpha 2 (Gfra2) Antikörper
  • GDNF family receptor alpha 2 (gfra2) Antikörper
  • GDNF family receptor alpha 2a (gfra2a) Antikörper
  • gdnfrb Antikörper
  • gfra2 Antikörper
  • nrtnr-alpha Antikörper
  • ntnra Antikörper
  • NTNRALPHA Antikörper
  • retl2 Antikörper
  • trnr2 Antikörper

Bezeichner auf Proteinebene für GFRA2

GDNF family receptor alpha-2 , GDNF receptor beta , GDNFR-alpha-2 , GDNFR-beta , GFR-alpha 2 , NTNR-alpha , PI-linked cell-surface accessory protein , RET ligand 2 , TGF-beta-related neurotrophic factor receptor 2 , TRN receptor, GPI-anchored , glial cell line derived neurotrophic factor receptor, beta , neurturin receptor alpha , GDNF receptor alpha-2 , GFR alpha 2 , GFR alpha-2 , GFR-alpha-2 , NRTNR-alpha , CDC42 binding protein kinase alpha (DMPK-like) , glial cell line derived neurotrophic factor family receptor alpha 2 , tyrosine kinase receptor ligand 2 , GDNF family receptor alpha 2 , GDNF family receptor alpha-2-like

GENE ID SPEZIES
2675 Homo sapiens
14586 Mus musculus
100157850 Sus scrofa
25136 Rattus norvegicus
395993 Gallus gallus
514036 Bos taurus
100127717 Xenopus (Silurana) tropicalis
100171804 Pongo abelii
405794 Danio rerio
609172 Canis lupus familiaris
100475044 Ailuropoda melanoleuca
100727079 Cavia porcellus
100146260 Equus caballus
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