anti-G Protein-Coupled Receptor 81 (GPR81) Antikörper

G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.. Zusätzlich bieten wir Ihnen G Protein-Coupled Receptor 81 Proteine (4) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GPR81 243270  
GPR81 689936  
GPR81 27198 Q9BXC0
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Top anti-G Protein-Coupled Receptor 81 Antikörper auf antikoerper-online.de

Showing 10 out of 95 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Western blot analysis of GPR81 expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Fledermaus Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: GPR81 Antibody [NLS2091] - Analysis of anti-FKSG80 / GPR81 antibody with pituitary, anterior at 3 ug/ ml. Immunohistochemistry-Paraffin: GPR81 Antibody [NLS2091] - Analysis of anti-FKSG80 / GPR81 antibody with human brain, glioblastoma. 0.05 mL Anmelden zum Anzeigen 10 bis 13 Tage
$514.63
Details
Human Kaninchen Unkonjugiert IHC (p) Immunohistochemistry: GPR81 Antibody [NLS2095] - Analysis of anti-FKSG80 / GPR81 antibody with pituitary. Immunohistochemistry-Paraffin: GPR81 Antibody [NLS2095] - Human Skin, Melanoma formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 0.05 mL Anmelden zum Anzeigen 10 bis 13 Tage
$514.63
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of GPR81 Antibody (C-term) in 293 cell line lysates (35ug/lane). This demonstrates the GPR81 antibody detected the GPR81 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: GPR81 Antibody [NBP1-51956] - Analysis of GPR81 in Human Liver lysate (35ug protein in RIPA buffer) using NBP1-51956 at 0.5g/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Human Colon, Epithelium (formalin-fixed, paraffin-embedded) stained with GPR81 antibody ABIN213369 at 11 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Fledermaus Kaninchen Unkonjugiert IHC, IHC (p) Anti-GPR81 antibody  ABIN1048875 IHC staining of human pituitary, anterior. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-FKSG80 / GPR81 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Anti-GPR81 antibody  ABIN1048876 IHC staining of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-FKSG80 / GPR81 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Human Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details

GPR81 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) ,


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Am meisten referenzierte anti-G Protein-Coupled Receptor 81 Antikörper

  1. Human Polyclonal GPR81 Primary Antibody für ELISA, WB - ABIN4274870 : Cai, Ren, Jin, Cheng, Kash, Chen, Wright, Taggart, Waters: Role of GPR81 in lactate-mediated reduction of adipose lipolysis. in Biochemical and biophysical research communications 2008 (PubMed)

  2. Human Polyclonal GPR81 Primary Antibody für IHC (p) - ABIN4315865 : Jeninga, Bugge, Nielsen, Kersten, Hamers, Dani, Wabitsch, Berger, Stunnenberg, Mandrup, Kalkhoven: Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81). in The Journal of biological chemistry 2009 (PubMed)

Weitere Antikörper gegen G Protein-Coupled Receptor 81 Interaktionspartner

Mouse (Murine) G Protein-Coupled Receptor 81 (GPR81) Interaktionspartner

  1. lactate can induce GPR81-independent metabolic changes that modulate macrophage pro-inflammatory activation.

  2. GPR81 expression increased during gestation, and peaked near labor. GPR81 is expressed in the uterus with high expression in myometrium. GPR81 mediates inflammation in the laboring uterus.

  3. Results indicate that lactate may aggravated ischemic brain injury by activating GPR81 and inhibition of GPR81 protects against ischemia-induced cell death via an antiapoptosis pathway

  4. Description of a GPR81 selective agonist with in vivo efficacy, inhibiting lipolysis without flushing.

  5. Lactate negatively regulates TLR induction of the NLRP3 (zeige NLRP3 Antikörper) inflammasome and production of IL1beta (zeige IL1B Antikörper), via ARRB2 (zeige ARRB2 Antikörper) and GPR81 in liver and pancreatic injury.

  6. chronic obesity reduces GPR109A (zeige HCAR2 Antikörper) and GPR81 expression in the adipose tissue, while acute in vitro LPS (zeige TLR4 Antikörper) treatment increases expression of GPR109A (zeige HCAR2 Antikörper) in adipocytes and macrophages.

  7. Inflammation decreases the expression of GPR81 in adipose tissue

  8. An autocrine lactate loop mediates insulin (zeige INS Antikörper)-dependent inhibition of lipolysis through GPR81.

  9. GPR81 couples to the Gi signaling pathway

  10. Data show that siRNA-mediated knockdown (zeige PPARG Antikörper)of PPARgamma in differentiated 3T3-L1 adip (zeige HCAR2 Antikörper)ocytes showe (zeige HCAR3 Antikörper)d a significant decrease in Gpr81 protein expression.

Human G Protein-Coupled Receptor 81 (GPR81) Interaktionspartner

  1. The novel role of HCAR1 in development of chemoresistance in cervical carcinoma HeLa cells via ABCB1 (zeige ABCB1 Antikörper) transporter up-regulation.

  2. Findings identify GPR81 as a tumor-promoting receptor in breast cancer progression and suggest a novel mechanism that regulates GPR81-dependent activation of the PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) signaling axis in tumor microenvironment.

  3. Activation of GPR81 decreases intracellular cAMP levels and inhibits PKA activity, leading to activation of TAZ (zeige TAZ Antikörper) and upregulation of PD-L1 (zeige CD274 Antikörper). This study reveals a critical role for lactate in the immune checkpoint pathway and an unexpected function of TAZ (zeige TAZ Antikörper) in tumor evasion of the T-cell-mediated immune response.

  4. Lactate receptor/HCAR1 expression in cervical carcinoma cells may contribute to the modulation of cellular DNA repair mechanisms.

  5. HCA1/3 are necessary for breast cancer cells to balance lipid/fatty acid metabolism.

  6. HCAR1 and monocarboxylate transporters activity is required for the L- and D-lactate-mediated enhancement of DNA repair and of HeLa cell survival.

  7. Description of a GPR81 selective agonist with in vivo efficacy, inhibiting lipolysis without flushing.

  8. Data support that GPR81 is important for cancer cell regulation of lactate transport mechanisms.

  9. Lactate negatively regulates TLR induction of the NLRP3 (zeige NLRP3 Antikörper) inflammasome and production of IL1beta (zeige IL1B Antikörper), via ARRB2 (zeige ARRB2 Antikörper) and GPR81 in liver and pancreatic injury.

  10. demonstrated that the C165-E166-S167-F168 motif at the second extracellular loop is critical for GPR81 function, and the conserved six Cys (zeige DNAJC5 Antikörper) residues at the extracellular regions are necessary for GPR81 function

G Protein-Coupled Receptor 81 (GPR81) Antigen-Profil

Protein Überblick

G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.

Genbezeichner und Symbole assoziert mit GPR81

  • hydroxycarboxylic acid receptor 1 (HCAR1) Antikörper
  • hydroxycarboxylic acid receptor 1-1 (hcar1-1) Antikörper
  • hydrocarboxylic acid receptor 1 (Hcar1) Antikörper
  • G protein-coupled receptor 81 (Gpr81) Antikörper
  • GPR81 Antikörper
  • gpr81-1 Antikörper
  • GPR104 Antikörper
  • HCA1 Antikörper
  • Hcar1 Antikörper
  • LACR1 Antikörper
  • TA-GPCR Antikörper

Bezeichner auf Proteinebene für GPR81

G protein-coupled receptor 81 , G-protein coupled receptor 81 , hydroxycarboxylic acid receptor 1 , G protein-coupled receptor 104 , G-protein coupled receptor 104 , T-cell activation G protein-coupled receptor , hydroxy-carboxylic acid receptor 1 , lactate receptor 1

GENE ID SPEZIES
452331 Pan troglodytes
538759 Bos taurus
570755 Danio rerio
702825 Macaca mulatta
100345808 Oryctolagus cuniculus
243270 Mus musculus
689936 Rattus norvegicus
486252 Canis lupus familiaris
27198 Homo sapiens
100153287 Sus scrofa
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