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GPR56 encodes a member of the G protein-coupled receptor family. Zusätzlich bieten wir Ihnen GPR56 Proteine (8) und GPR56 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal GPR56 Primary Antibody für CyTOF, FACS - ABIN4899959
Stoveken, Hajduczok, Xu, Tall: Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist. in Proceedings of the National Academy of Sciences of the United States of America 2015
Show all 2 Pubmed References
Gpr56 regulates oligodendrocyte development via interactions with Galpha12 (zeige GNA12 Antikörper)/13 and RhoA (zeige RHOA Antikörper)
GPR56 inhibits natural cytotoxicity of human NK cells.
Functional relevance of GPR56 expression (zeige HOXA9 Antikörper)was va (zeige MEIS1 Antikörper)lidated in m (zeige RUNX1 Antikörper)ice, in which co-expression of Gpr56 significantly accelerated HOXA9-induced leukemogenesis
expression and activation of GPR56 may modulate melanoma progression in part by inducing IL-6 (zeige IL6 Antikörper) production after N-terminal fragment dissociation and C-terminal fragment self-activation
Disease-associated extracellular loop mutations in the adhesion G protein-coupled receptor (zeige ADRA1A Antikörper) G1 (ADGRG1; GPR56) differentially regulate downstream signaling
GPR56 regulates the proliferation and invasion capacity of osteosarcoma cells.
High GPR56 expression was significantly associated with high-risk genetic subgroups and poor outcome in patients with acute myeloid leukemia (zeige BCL11A Antikörper) and identifies cancer stem cells with high repopulating potential.
Data suggest that agonist-induced signal transduction via either GPR56/ADGRG1 or BAI1 (zeige BAI1 Antikörper)/ADGRB1 does not require conserved membrane-proximal stalk region of these proteins; ADGRG1 may participate in stalk-dependent and stalk-independent signaling.
Agonistic antibodies reveal the function of GPR56 in human glioma U87-MG cells
we knocked down GPR56 in cardiomyocytes and found that GPR56 promoted Ang II (zeige AGT Antikörper)-induced cardiomyocyte hypertrophy and it contributed to PCBP2 (zeige PCBP2 Antikörper) effects on cardiomyocyte hypertrophy
GPR56 and GPR110 (zeige GPR110 Antikörper) are activated by exposure of a cryptic tethered agonist
determine the crystal structure of the GPR56 extracellular domain.
knockdown of Gpr56 delayed onset of HOXA9 (zeige HOXA9 Antikörper)/MEIS1 (zeige MEIS1 Antikörper)-induced AML (zeige RUNX1 Antikörper)
GPR56 is a cell-autonomous regulator of oligodendrocyte development
Although GPR56 is abundantly and selectively expressed by primitive HSPCs, its high level expression is largely dispensable for steady-state and regenerative hematopoiesis.
Data show that Gpr56, a G-coupled protein receptor, is required for hematopoietic cluster formation during transdifferentiation process in endothelial to hematopoietic cell transition (EHT (zeige CBFA2T2 Antikörper)).
These data illustrate a signaling pathway through GPR56 which regulates muscle hypertrophy associated with resistance/loading-type exercise.
adhesion G protein-coupled receptor (zeige GPR34 Antikörper) GPR56-mediated RhoA (zeige RHOA Antikörper) activation induced by collagen III stimulation
Role for TG2 (zeige TGM2 Antikörper) in GPR56-mediated melanoma inhibition. The uncovered antagonistic relationship between GPR56 and TG2 (zeige TGM2 Antikörper) proposes a mechanism by which extracellular matrix accumulation/crosslinking in tumors may be reversed.
This gene encodes a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene.
G protein-coupled receptor 56
, G-protein coupled receptor 56-like
, 7-transmembrane protein with no EGF-like N-terminal domains-1
, G-protein coupled receptor 56
, secretin receptor
, serpentine receptor cyt28