anti-G Protein-Coupled Receptor 17 (GPR17) Antikörper

Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Zusätzlich bieten wir Ihnen GPR17 Proteine (4) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GPR17 2840 Q13304
GPR17 574402 Q6NS65
GPR17 767613 Q09QM4
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Top anti-GPR17 Antikörper auf antikoerper-online.de

Showing 10 out of 106 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ICC, IHC (p) Immunocytochemistry/Immunofluorescence: GPR17 Antibody [NLS4229] - immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells. Immunohistochemistry-Paraffin: GPR17 Antibody [NLS4229] - IHC staining of human brain, neurons and glia. 0.05 mL Anmelden zum Anzeigen 10 bis 13 Tage
$514.63
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of GPR17 expression in HEK293T (A), Jurkat (B), NIH3T3 (C), rat kidney (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Ziege Unkonjugiert ELISA, WB Antibody (0.1µg/ml) staining of Human Cerebellum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Antibody (0.3µg/ml) staining of Rat Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert IF, ELISA Immunofluorescence analysis of HeLa cells, using GPR17 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from LOVO cells, using GPR17 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Huhn Ziege Unkonjugiert ELISA, IHC, IHC (p), WB Anti-GPR17 antibody IHC staining of human heart, desmosomes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101834 concentration 10 ug/ml. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Anti-GPR17 antibody  ABIN1048752 IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert ICC, IHC, IHC (p) Anti-GPR17 antibody  ABIN1048753 IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p) Anti-GPR17 antibody  ABIN1048754 IHC staining of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of GPR17 Antibody (Center) (ABIN653809) in MDA-MB435 cell line lysates (35 µg/lane). GPR17 (arrow) was detected using the purified polyclonal antibody. GPR17 Antibody (Center) (ABIN653809) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details

GPR17 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GPR17 Antikörper

  1. Human Polyclonal GPR17 Primary Antibody für ICC, IHC (p) - ABIN271042 : Ciana, Fumagalli, Trincavelli, Verderio, Rosa, Lecca, Ferrario, Parravicini, Capra, Gelosa, Guerrini, Belcredito, Cimino, Sironi, Tremoli, Rovati, Martini, Abbracchio: The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor. in The EMBO journal 2006 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal GPR17 Primary Antibody für ELISA, WB - ABIN4315679 : Parravicini, Ranghino, Abbracchio, Fantucci: GPR17: molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors. in BMC bioinformatics 2008 (PubMed)

Weitere Antikörper gegen GPR17 Interaktionspartner

Human G Protein-Coupled Receptor 17 (GPR17) Interaktionspartner

  1. In silico and ex vivo validation experiments provided the deep understanding of ligand binding with GPR17 and the present findings reported here may lead to use these two compounds as a potential activator of GPR17 for therapeutic intervention.

  2. Results show a crucial role of SNX27 (zeige SNX27 Antikörper) in modulating GPR17 levels by means of a post-translational mechanism and highlights the relationship between the trafficking of the receptor through the endomembrane system and oligodendrocyte differentiation; and provide novel evidence of impairment of GPR17 expression and oligodendrocyte maturation in a mouse model of Down syndrome that is characterized by SNX27 (zeige SNX27 Antikörper) down-regulation.

  3. uracil nucleotides and cysteinyl leukotrienes do not activate human, mouse, or rat GPR17 in various cellular backgrounds.

  4. GPR17 gene disruption does not alter food intake or glucose homeostasis in mice.

  5. This review summarizes knowledge about role of GPR17 receptors in physiology and pathology of nervous system, with special attention to remyelination processes.

  6. Low levels of GRK2 (zeige ADRBK1 Antikörper)/GRK5 (zeige GRK5 Antikörper) causes a slow and not complete desensitization/down-regulation of GPR17.

  7. Data indicate that small molecule MDL29,951 activates human, mouse and rat orphan G protein-coupled receptor (zeige GPRC5D Antikörper) GPR17.

  8. Data validate GPR17 as a target for neurorepair

  9. Nucleotides, nucleotide sugars, and cysteinyl leukotrienes do not promote activation of GPR17 in five different cell lines, nor does GPR17 have signaling properties.

  10. analysis of agonist-induced trafficking of native GPR17 in oligodendroglial cells

Mouse (Murine) G Protein-Coupled Receptor 17 (GPR17) Interaktionspartner

  1. The role of oligodendrocyte precursor cells expressing the GPR17 receptor in brain remodeling after stroke.

  2. Results show a crucial role of SNX27 (zeige SNX27 Antikörper) in modulating GPR17 levels by means of a post-translational mechanism and highlights the relationship between the trafficking of the receptor through the endomembrane system and oligodendrocyte differentiation; and provide novel evidence of impairment of GPR17 expression and oligodendrocyte maturation in a mouse model of Down syndrome that is characterized by SNX27 (zeige SNX27 Antikörper) down-regulation.

  3. The loss of Gpr17 in mice led to precocious myelination and an earlier onset of remyelination after demyelination

  4. uracil nucleotides and cysteinyl leukotrienes do not activate human, mouse, or rat GPR17 in various cellular backgrounds.

  5. GPR17(+) cells--in contrast to GPR17(-) NG2 (zeige Vcan Antikörper)-glia--did not differentiate within 3 months, a peculiarity that was overcome after cerebral damage induced by acute injury or ischemia

  6. stimulation of GPR17 by the small molecule agonist MDL29,951 (2-carboxy-4,6-dichloro-1H-indole-3-propionic acid) decreases myelin basic protein (zeige MBP Antikörper) expression levels mainly by triggering the Galphai/o signaling pathway.

  7. Agrp (zeige AGRP Antikörper)-Gpr17(-/-) mice show reduced food intake, increased relative energy expenditure, and increased satiety, resulting in leanness and reduced body fat. They also show increased central nervous system sensitivity to insulin (zeige INS Antikörper) and leptin (zeige LEP Antikörper).

  8. The mouse GPR17 receptor plays a central role in the early response of cardiac stromal cells to ischaemia.

  9. Data indicate that small molecule MDL29,951 activates human, mouse and rat orphan G protein-coupled receptor (zeige GPRC5C Antikörper) GPR17.

  10. GPR17 is a marker for progenitor progression within the oligodendroglial lineage that participates in postacute reactivity of NG2 (zeige Vcan Antikörper)-proteoglycan (zeige Vcan Antikörper) expressing cells in different injury paradigms.

GPR17 Antigen-Profil

Protein Überblick

Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.

Genbezeichner und Symbole assoziert mit GPR17

  • G protein-coupled receptor 17 (GPR17) Antikörper
  • G protein-coupled receptor 17 (Gpr17) Antikörper
  • AI853548 Antikörper
  • GPR17 Antikörper

Bezeichner auf Proteinebene für GPR17

G protein-coupled receptor 17 , uracil nucleotide/cysteinyl leukotriene receptor-like , uracil nucleotide/cysteinyl leukotriene receptor , G-protein coupled receptor 17 , P2Y-like receptor , R12 , UDP/CysLT receptor

GENE ID SPEZIES
699576 Macaca mulatta
769024 Gallus gallus
100444185 Pongo abelii
100593986 Nomascus leucogenys
100611956 Pan troglodytes
782442 Bos taurus
2840 Homo sapiens
574402 Mus musculus
767613 Rattus norvegicus
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