Fumarate Hydratase (FH) ELISA Kits

The protein encoded by FH is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. Zusätzlich bieten wir Ihnen FH Antikörper (194) und FH Proteine (22) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
FH 2271 P07954
FH 24368  
FH 14194 P97807
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Top FH ELISA Kits auf antikoerper-online.de

Showing 10 out of 24 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 7.8 pg/mL 31.2-2000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
Details
Maus 1.0 ng/mL 10-250 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Schwein 1.0 ng/mL 10-250 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Meerschweinchen
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Kaninchen
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Ratte
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Huhn
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Affe
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Schaf
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Hund
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
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Weitere ELISA Kits für FH Interaktionspartner

Human Fumarate Hydratase (FH) Interaktionspartner

  1. Induction of ferroptosis in fumarate hydratase-inactivated tumors represents an opportunity for synthetic lethality in cancer.

  2. A case series of 2 sisters in their 20s who presented with isolated uterine leiomyomas and were found to carry a novel mutation for the fumarate hydratase gene.

  3. The clinical spectrum associated with hereditary leiomyomatosis and renal cell carcinoma syndrome in French FH mutation carriers has been reassessed.

  4. As with many emerging cancer syndromes, the phenotypic spectrum ofhereditary leiomyomatosis and renal cell cancer( HLRCC) is likely to expand as the FH gene becomes incorporated on more multiplex germline panels, which will also help to clarify the potential involvement of other tumor types in HLRCC

  5. We show that the mechanism of fumarate hydratase distribution is alternative transcription initiation from a broad promoter.

  6. fumarate increases ferritin (zeige FTL ELISA Kits) gene transcription by activating the NRF2 (zeige GABPA ELISA Kits) (nuclear factor [erythroid-derived 2]-like 2) transcription factor.

  7. FH-Ser75 phosphorylation level inversely correlates with the OGT (zeige OGT ELISA Kits) level and poor prognosis in pancreatic cancer patients. Report mechanism underlying transcription regulation by FH and the linkage between dysregulated OGT (zeige OGT ELISA Kits) activity and growth advantage of cancer cells under glucose deficiency.

  8. Loss of FH immunohistochemical (IHC) expression in cutaneous leiomyomas is a sensitive and specific marker for detection of hereditary leiomyomatosis and renal cell carcinoma (HLRCC). FH expression by IHC was absent in 9 specimens and retained in 85 specimens and 2 cases were equivocal with minimal FH expression while succinate dehydrogenase B (zeige SDHB ELISA Kits) expression was retained in 95 specimens and equivocal in 1 specimen.

  9. LSH promoted cancer progression in part by regulating expression of fumarate hydratase (FH).

  10. Cascade FH mutation screening enabled the early diagnosis of a renal tumour in an asymptomatic parent of a child with fumarate hydratase deficiency, resulting in timely and possibly life-saving treatment.

Mouse (Murine) Fumarate Hydratase (FH) Interaktionspartner

  1. roles for fumarate metabolism in hematopoietic stem cell (HSC) maintenance and hematopoietic differentiation and reveal a differential requirement for mitochondrial Fh1 in normal hematopoiesis and leukemia propagation.

  2. Adipose-Specific Deficiency of Fumarate Hydratase in Mice Protects Against Obesity, Hepatic Steatosis, and Insulin (zeige INS ELISA Kits) Resistance.

  3. Reexpression of cytosolic FH in FH1-deficient mice is critical for the suppression of renal cyst development and restoration of defects in the arginine biosynthesis pathway.

  4. Tumor-derived FH and SDH mutations accumulate fumarate and succinate, leading to enzymatic inhibition of multiple alpha-KG-dependent dioxygenases and consequent alterations of genome-wide histone and DNA methylation.

  5. identification of a metabolic pathway that is induced in Fh1-deficient cells to demonstrate that inhibition of haem oxygenation is synthetically lethal when combined with Fh1 deficiency, providing a new potential target for treating HLRCC patients

  6. These experiments demonstrated that upregulation of HIF-1alpha (zeige HIF1A ELISA Kits) occurs as a direct consequence of FH inactivation.

  7. progression of tumors where FH is lost might be boosted by activation of the MET oncogene (zeige RAB1A ELISA Kits), which is able to drive cell-autonomous tumor progression

FH Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

Genbezeichner und Symbole assoziert mit Fumarate Hydratase (FH) ELISA Kits

  • fumarate hydratase (FH) Antikörper
  • fumarate hydratase (fumH) Antikörper
  • fumarate hydratase (Fh) Antikörper
  • fumarate hydratase (fh) Antikörper
  • fumarate hydratase 1 (Fh1) Antikörper
  • DDBDRAFT_0205237 Antikörper
  • DDBDRAFT_0231397 Antikörper
  • DDBDRAFT_0231400 Antikörper
  • DDB_0205237 Antikörper
  • DDB_0231397 Antikörper
  • DDB_0231400 Antikörper
  • Fh Antikörper
  • Fh-1 Antikörper
  • Fh1 Antikörper
  • HLRCC Antikörper
  • im:7152785 Antikörper
  • LRCC Antikörper
  • MCL Antikörper
  • MCUL1 Antikörper
  • ns:zf-e152 Antikörper
  • zf-e152 Antikörper
  • zgc:66253 Antikörper
  • zgc:77498 Antikörper

Bezeichner auf Proteinebene für Fumarate Hydratase (FH) ELISA Kits

fumarate hydratase, mitochondrial , fumarate hydratase , fumarase , fumarate hydratase 1 , EF-3

GENE ID SPEZIES
100302102 Ovis aries
100060381 Equus caballus
707542 Macaca mulatta
420969 Gallus gallus
457851 Pan troglodytes
100172452 Pongo abelii
8622588 Dictyostelium discoideum AX4
2271 Homo sapiens
24368 Rattus norvegicus
480092 Canis lupus familiaris
100627128 Sus scrofa
520260 Bos taurus
393938 Danio rerio
14194 Mus musculus
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