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FIGLA encodes a protein that functions in postnatal oocyte-specific gene expression. Zusätzlich bieten wir Ihnen FIGLA Antikörper (24) und FIGLA Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
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GFP positive cells showed the expression of germ cell markers Vasa (zeige DDX4 ELISA Kits), meiotic specific gene Stra8, Scp3 (zeige SYCP3 ELISA Kits), oocyte markers Gdf9 (zeige GDF9 ELISA Kits), Zp3 (zeige ZP3 ELISA Kits) and Figla, indicating that this method could be used for the purification and selection of female germ cells
Data suggest that a dynamic DNA CpG methylation in Sohlh2 and Figlalpha promoters, but not in the intron and exon sequences, is linked to regulation of gene expression, even though CpG islands are also present in their introns or exons.
physiological expression of Figla plays a critical dual role in activation of oocyte-associated genes and repression of sperm-associated genes during normal postnatal oogenesis
FIGLA is a central regulator of oocyte-specific genes that play roles in folliculogenesis, fertilization and early development.
study identified an association between FIGLA gene variants and the occurrence of premature ovarian failure(POF (zeige POF1B ELISA Kits)) in the Indian population; findings suggest that the c.427G->C and c.557C->T alleles lead to an increased risk of POF (zeige POF1B ELISA Kits) in Indian women
These results suggest that FIGLA is involved in continued oocyte survival as primordial follicles form in the human as in the rodent ovary.
the p.140 delN mutation disrupted FIGLA binding to the TCF3 (zeige TCF3 ELISA Kits) helix-loop-helix (HLH) domain. Our findings show that a subset of Chinese women with sporadic, premature ovarian failure harbor mutations in FIGLA.
This gene encodes a protein that functions in postnatal oocyte-specific gene expression. The protein is a basic helix-loop-helix transcription factor that regulates multiple oocyte-specific genes, including genes involved in folliculogenesis and those that encode the zona pellucida. Mutations in this gene cause premature ovarian failure type 6.
, factor in the germline alpha
, transcription factor FIGa
, class C basic helix-loop-helix protein 8
, folliculogenesis-specific basic helix-loop-helix protein
, folliculogenesis specific basic helix-loop-helix
, folliculogenesis specific bHLH transcription factor L homeolog