Flightless I Homolog (Drosophila) Proteine (FLII)

FLII encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. Zusätzlich bieten wir Ihnen Flightless I Homolog (Drosophila) Antikörper (38) und Flightless I Homolog (Drosophila) Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
FLII 2314 Q13045
FLII 14248 Q9JJ28
Ratte FLII FLII 287375  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top Flightless I Homolog (Drosophila) Proteine auf antikoerper-online.de

Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Hefe Maus His tag 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$578.60
Details
Escherichia coli (E. coli) Human S tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$672.00
Details

FLII Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine) ,

Weitere Proteine zu Flightless I Homolog (Drosophila) (FLII) Interaktionspartnern

Human Flightless I Homolog (Drosophila) (FLII) Interaktionspartner

  1. Low FLII expression is associated with lung carcinoma.

  2. Data show that the ability of Ca(2+) to accentuate the activity of NLRP3 inflammasome is abrogated in Flightless-I (FliI) and leucine-rich repeat FliI-interaction protein 2 (LRRFIP2)-knockdown macrophages.

  3. Together, the data demonstrate the critical requirement of GGAA-microsatellites as EWS (zeige EWSR1 Proteine)/FLI activating response elements in vivo and reveal an unexpected role for the EWS (zeige EWSR1 Proteine) portion of the EWS (zeige EWSR1 Proteine)/FLI fusion in binding to sweet-spot GGAA-microsatellites.

  4. FLII is a component of the ChREBP (zeige MLXIPL Proteine) transcriptional complex and negatively regulates ChREBP (zeige MLXIPL Proteine) function in cancer cells.

  5. Demonstrate an important role for Flii in the development and regulation of the epidermal barrier, which may contribute to the impaired healing and skin fragility of epidermolysis bullosa patients.

  6. FLII is associated with SENP3 and the MLL1/2 complex and FLII is indispensible for H3K4 methylation and proper loading of active RNA polymerase II at this gene locus.

  7. Flightless-I (Drosophila) homolog (FLII) activates TGFbeta1 (zeige TGFB1 Proteine)-mediated expression of COL1A2 (zeige COL1A2 Proteine) gene.

  8. Studies suggest that Flii enhances cutaneous squamous cell carcinoma progression by decreasing apoptosis and enhancing tumor cell invasion.

  9. FLII plays a tumor-suppressive role and serves as a crucial determinant of resistance of prostate cancer to endocrine therapies.

  10. These data suggest FLII as a key regulator of ERalpha-mediated transcription through its role in regulating chromatin accessibility for the binding of RNA Polymerase II and possibly other transcriptional coactivators.

Mouse (Murine) Flightless I Homolog (Drosophila) (FLII) Interaktionspartner

  1. Fluorescence resonance energy transfer experiments showed that FliI-NMMIIA interactions require Ca(2 (zeige CA2 Proteine)+) influx. We conclude that Ca(2 (zeige CA2 Proteine)+) influx through the TRPV4 (zeige TRPV4 Proteine) channel regulates FliI-NMMIIA interaction, which in turn enables generation of the cell extensions essential for collagen remodeling

  2. Flii genetic expression is enhances tissue regeneration, after claw amputation.

  3. Studies suggest that Flii enhances cutaneous squamous cell carcinoma progression by decreasing apoptosis and enhancing tumor cell invasion.

  4. P-Rex1 stimulates migration through enhancing the interaction between Rac1 and the actin-remodelling protein.

  5. Genes downstream from Flii, including TGF-beta1 (zeige TGFB1 Proteine) and TGF-beta3 (zeige TGFB3 Proteine), showed significantly altered expression confirming a functional effect of the Rhodamine-Flii small interfering RNA on gene expression

  6. FliI interacts with NMMIIA to promote cell extension formation, which enables collagen remodeling in fibroblasts.

  7. FLII functions in PPARgamma (zeige PPARG Proteine) activation as a molecular switch to repress transcriptional activity by interrupting formation of the PPARgamma (zeige PPARG Proteine)/RXRalpha (zeige RXRA Proteine) complex.

  8. LRRFIP2 (zeige LRRFIP2 Proteine) inhibits NLRP3 (zeige NLRP3 Proteine) inflammasome activation by recruiting the caspase-1 (zeige CASP1 Proteine) inhibitor Flightless-I, thus outlining a new mechanism for negative regulation of NLRP3 (zeige NLRP3 Proteine) inflammasome.

  9. increasing the level of Flii in diabetic mouse wounds led to increased TLR4 (zeige TLR4 Proteine) and NF- kappa B (zeige NFKB1 Proteine) production. Treatment of murine diabetic wounds with neutralising antibodies to Flii led to an improvement in healing with decreased expression of TLR4 (zeige TLR4 Proteine)

  10. Using a mouse model of epidermolysis bullosa acquisita, the effect of "mopping up" Flii using Flii-neutralizing antibodies before, during, and after blister formation was determined.

Cow (Bovine) Flightless I Homolog (Drosophila) (FLII) Interaktionspartner

  1. These findings strongly demonstrate that the three single nucleotide polymorphisms of FLII gene could be utilized as molecular markers for future assisted selection in cattle breeding program.

Zebrafish Flightless I Homolog (Drosophila) (FLII) Interaktionspartner

  1. Embryos defective in flightless I homolog (flii), which encodes for an actin-regulating protein, exhibit normal coilings at 24 hours post fertilization (hpf) that is followed by significantly slower burst swimming at 48 hpf.

Caenorhabditis elegans (C. elegans) Flightless I Homolog (Drosophila) (FLII) Interaktionspartner

  1. fli-1 plays an important role in regulating the actin-dependent events during C. elegans development.

  2. FLI-1 controls germ line morphogenesis and rachis organization

Flightless I Homolog (Drosophila) (FLII) Protein Überblick

Protein Überblick

This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. The gene is located within the Smith-Magenis syndrome region on chromosome 17.

Genbezeichner und Symbole assoziert mit FLII

  • FLII, actin remodeling protein (FLII)
  • flightless I actin binding protein (Flii)
  • FLII, actin remodeling protein (Flii)
  • flightless I actin binding protein (flii)
  • protein flightless-1 homolog (LOC585336)
  • FLII, actin remodeling protein (flii)
  • protein flightless-1 homolog (LOC100640615)
  • FLII, actin remodeling protein S homeolog (flii.S)
  • Protein flightless-1 homolog (fli-1)
  • 3632430F08Rik Protein
  • DKFZp459O043 Protein
  • FLI Protein
  • Fli1 Protein
  • flightless Protein
  • Fliih Protein
  • FLIL Protein
  • im:7141769 Protein

Bezeichner auf Proteinebene für FLII

protein flightless-1 homolog , flightless I homolog (Drosophila) , flightless-I homolog , flightless I homolog

GENE ID SPEZIES
2314 Homo sapiens
14248 Mus musculus
287375 Rattus norvegicus
416515 Gallus gallus
454486 Pan troglodytes
479521 Canis lupus familiaris
514446 Bos taurus
560281 Danio rerio
585336 Strongylocentrotus purpuratus
700471 Macaca mulatta
100051793 Equus caballus
100173989 Pongo abelii
100398338 Callithrix jacchus
100475330 Ailuropoda melanoleuca
100543687 Meleagris gallopavo
100553018 Anolis carolinensis
100600354 Nomascus leucogenys
100619473 Monodelphis domestica
100640615 Amphimedon queenslandica
444748 Xenopus laevis
176215 Caenorhabditis elegans
100728597 Cavia porcellus
Ausgewählte Anbieter für Flightless I Homolog (Drosophila) Proteine (FLII)
Haben Sie etwas anderes gesucht?