anti-Flightless I Homolog (Drosophila) (FLII) Antikörper

FLII encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. Zusätzlich bieten wir Ihnen Flightless I Homolog (Drosophila) Kits (5) und Flightless I Homolog (Drosophila) Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FLII 2314 Q13045
FLII 14248 Q9JJ28
FLII 287375  
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Top anti-Flightless I Homolog (Drosophila) Antikörper auf antikoerper-online.de

Showing 10 out of 38 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-FLII Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>OVCAR-3 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis FLII using HepG2 whole cell lysates 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Pferd Kaninchen Unkonjugiert IHC, IHC (p) Anti-FLII / FLI antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101558 dilution 41552 ug/ml. Anti-FLII / FLI antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1101558 dilution 41552 ug/ml. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, IHC (p), WB Human, Heart: Formalin-Fixed Paraffin-Embedded (FFPE) Human, Prostate: Formalin-Fixed Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$727.83
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with FLII polyclonal antibody  at 1:250-1:500 dilution. Immunofluorescent staining of human cell line A-431 with FLII polyclonal antibody  at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli, cytoplasm. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$460.00
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human Lung Tissue; Lane2: Porcine Kidney Tissue. Figure. Western Blot; Sample: Recombinant FLII, Human. 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$350.00
Details
Human Kaninchen Unkonjugiert ICC, WB   100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$507.83
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cell lines, using FLII antibody. 120 μL Anmelden zum Anzeigen 12 bis 14 Tage
$251.90
Details
Human Kaninchen Unkonjugiert WB FLII antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 9 bis 11 Tage
$473.93
Details
Maus Kaninchen Biotin ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$581.17
Details

Weitere Antikörper gegen Flightless I Homolog (Drosophila) Interaktionspartner

Human Flightless I Homolog (Drosophila) (FLII) Interaktionspartner

  1. Low FLII expression is associated with lung carcinoma.

  2. Data show that the ability of Ca(2+) to accentuate the activity of NLRP3 inflammasome is abrogated in Flightless-I (FliI) and leucine-rich repeat FliI-interaction protein 2 (LRRFIP2)-knockdown macrophages.

  3. Together, the data demonstrate the critical requirement of GGAA-microsatellites as EWS (zeige EWSR1 Antikörper)/FLI activating response elements in vivo and reveal an unexpected role for the EWS (zeige EWSR1 Antikörper) portion of the EWS (zeige EWSR1 Antikörper)/FLI fusion in binding to sweet-spot GGAA-microsatellites.

  4. FLII is a component of the ChREBP (zeige MLXIPL Antikörper) transcriptional complex and negatively regulates ChREBP (zeige MLXIPL Antikörper) function in cancer cells.

  5. Demonstrate an important role for Flii in the development and regulation of the epidermal barrier, which may contribute to the impaired healing and skin fragility of epidermolysis bullosa patients.

  6. FLII is associated with SENP3 and the MLL1/2 complex and FLII is indispensible for H3K4 methylation and proper loading of active RNA polymerase II at this gene locus.

  7. Flightless-I (Drosophila) homolog (FLII) activates TGFbeta1 (zeige TGFB1 Antikörper)-mediated expression of COL1A2 (zeige COL1A2 Antikörper) gene.

  8. Studies suggest that Flii enhances cutaneous squamous cell carcinoma progression by decreasing apoptosis and enhancing tumor cell invasion.

  9. FLII plays a tumor-suppressive role and serves as a crucial determinant of resistance of prostate cancer to endocrine therapies.

  10. These data suggest FLII as a key regulator of ERalpha-mediated transcription through its role in regulating chromatin accessibility for the binding of RNA Polymerase II and possibly other transcriptional coactivators.

Mouse (Murine) Flightless I Homolog (Drosophila) (FLII) Interaktionspartner

  1. Fluorescence resonance energy transfer experiments showed that FliI-NMMIIA interactions require Ca(2 (zeige CA2 Antikörper)+) influx. We conclude that Ca(2 (zeige CA2 Antikörper)+) influx through the TRPV4 (zeige TRPV4 Antikörper) channel regulates FliI-NMMIIA interaction, which in turn enables generation of the cell extensions essential for collagen remodeling

  2. Flii genetic expression is enhances tissue regeneration, after claw amputation.

  3. Studies suggest that Flii enhances cutaneous squamous cell carcinoma progression by decreasing apoptosis and enhancing tumor cell invasion.

  4. P-Rex1 stimulates migration through enhancing the interaction between Rac1 and the actin-remodelling protein.

  5. Genes downstream from Flii, including TGF-beta1 (zeige TGFB1 Antikörper) and TGF-beta3 (zeige TGFB3 Antikörper), showed significantly altered expression confirming a functional effect of the Rhodamine-Flii small interfering RNA on gene expression

  6. FliI interacts with NMMIIA to promote cell extension formation, which enables collagen remodeling in fibroblasts.

  7. FLII functions in PPARgamma (zeige PPARG Antikörper) activation as a molecular switch to repress transcriptional activity by interrupting formation of the PPARgamma (zeige PPARG Antikörper)/RXRalpha (zeige RXRA Antikörper) complex.

  8. LRRFIP2 (zeige LRRFIP2 Antikörper) inhibits NLRP3 (zeige NLRP3 Antikörper) inflammasome activation by recruiting the caspase-1 (zeige CASP1 Antikörper) inhibitor Flightless-I, thus outlining a new mechanism for negative regulation of NLRP3 (zeige NLRP3 Antikörper) inflammasome.

  9. increasing the level of Flii in diabetic mouse wounds led to increased TLR4 (zeige TLR4 Antikörper) and NF- kappa B (zeige NFKB1 Antikörper) production. Treatment of murine diabetic wounds with neutralising antibodies to Flii led to an improvement in healing with decreased expression of TLR4 (zeige TLR4 Antikörper)

  10. Using a mouse model of epidermolysis bullosa acquisita, the effect of "mopping up" Flii using Flii-neutralizing antibodies before, during, and after blister formation was determined.

Cow (Bovine) Flightless I Homolog (Drosophila) (FLII) Interaktionspartner

  1. These findings strongly demonstrate that the three single nucleotide polymorphisms of FLII gene could be utilized as molecular markers for future assisted selection in cattle breeding program.

Zebrafish Flightless I Homolog (Drosophila) (FLII) Interaktionspartner

  1. Embryos defective in flightless I homolog (flii), which encodes for an actin-regulating protein, exhibit normal coilings at 24 hours post fertilization (hpf) that is followed by significantly slower burst swimming at 48 hpf.

Caenorhabditis elegans (C. elegans) Flightless I Homolog (Drosophila) (FLII) Interaktionspartner

  1. fli-1 plays an important role in regulating the actin-dependent events during C. elegans development.

  2. FLI-1 controls germ line morphogenesis and rachis organization

Flightless I Homolog (Drosophila) (FLII) Antigen-Profil

Protein Überblick

This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. The gene is located within the Smith-Magenis syndrome region on chromosome 17.

Genbezeichner und Symbole assoziert mit FLII

  • FLII, actin remodeling protein (FLII) Antikörper
  • flightless I actin binding protein (Flii) Antikörper
  • FLII, actin remodeling protein (Flii) Antikörper
  • flightless I actin binding protein (flii) Antikörper
  • protein flightless-1 homolog (LOC585336) Antikörper
  • FLII, actin remodeling protein (flii) Antikörper
  • protein flightless-1 homolog (LOC100640615) Antikörper
  • FLII, actin remodeling protein S homeolog (flii.S) Antikörper
  • Protein flightless-1 homolog (fli-1) Antikörper
  • 3632430F08Rik Antikörper
  • DKFZp459O043 Antikörper
  • FLI Antikörper
  • Fli1 Antikörper
  • flightless Antikörper
  • Fliih Antikörper
  • FLIL Antikörper
  • im:7141769 Antikörper

Bezeichner auf Proteinebene für FLII

protein flightless-1 homolog , flightless I homolog (Drosophila) , flightless-I homolog , flightless I homolog

GENE ID SPEZIES
2314 Homo sapiens
14248 Mus musculus
287375 Rattus norvegicus
416515 Gallus gallus
454486 Pan troglodytes
479521 Canis lupus familiaris
514446 Bos taurus
560281 Danio rerio
585336 Strongylocentrotus purpuratus
700471 Macaca mulatta
100051793 Equus caballus
100173989 Pongo abelii
100398338 Callithrix jacchus
100475330 Ailuropoda melanoleuca
100543687 Meleagris gallopavo
100553018 Anolis carolinensis
100600354 Nomascus leucogenys
100619473 Monodelphis domestica
100640615 Amphimedon queenslandica
444748 Xenopus laevis
176215 Caenorhabditis elegans
100728597 Cavia porcellus
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