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FBLN2 encodes an extracellular matrix protein, which belongs to the fibulin family. Zusätzlich bieten wir Ihnen Fibulin 2 Antikörper (76) und Fibulin 2 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.
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Human FBLN2 ELISA Kit für Sandwich ELISA - ABIN418849
Serra, Rosales, Masana, Vallvé: Simvastatin Increases Fibulin-2 Expression in Human Coronary Artery Smooth Muscle Cells via RhoA/Rho-Kinase Signaling Pathway Inhibition. in PLoS ONE 2015
Using in vitro approaches and cultured breast cancer cell lines authors demonstrate that Fibulin-2 is a better substrate for ADAMTS-5 (zeige ADAMTS5 ELISA Kits) than it is for ADAMTS-4 (zeige ADAMTS4 ELISA Kits). Fibulin-2 degradation is associated to an enhancement of the invasive potential of T47D, MCF-7 and SK-BR-3 cells.
levels of fibulin 2 dramatically increased in the retinal pigment epithelium following retinal detachment, suggesting a direct role for fibulin 2 in the re-attachment of the retina to the retinal pigment epithelium.
Study identified and validated a novel bona fide target of miR-1 (zeige FSD1 ELISA Kits), Fibullin-2 (Fbln2), a secreted protein implicated in extracellular matrix remodeling.
Data provide evidence that FBLN2 short isoform (FBLN2S) has an important tumor-suppressive and anti-angiogenic role in nasopharyngeal carcinoma (NPC (zeige NPC1 ELISA Kits)).
fibulin-1 (zeige FBLN1 ELISA Kits) and -2 respond differentially to single and repeated damaging noxae, and their expression is differently present in liver cells
Our study indicates that Ang II (zeige AGT ELISA Kits) cannot induce TGF-beta (zeige TGFB1 ELISA Kits) activation without fibulin-2 and that fibulin-2 has an essential role in Ang II (zeige AGT ELISA Kits)-induced TGF-beta (zeige TGFB1 ELISA Kits) signaling and subsequent myocardial fibrosis. Fibulin-2 can be considered as a critical regulator of TGF-beta (zeige TGFB1 ELISA Kits) that induces myocardial fibrosis.
These findings demonstrate a prominent role for alpha3beta1 in immortalized/transformed keratinocytes in regulating fibulin-2 and other genes that promote matrix remodeling and invasion.
FBLN2 and VCAN (zeige Vcan ELISA Kits) were both preferentially expressed in the mammary gland during times of epithelial expansion in TEB-enriched tissue and co-localised specifically in cap cell.
integrin alpha3beta1 has a role in basement membrane stability through fibulin-2 induction, both in neonatal skin and in adult wounds
Data conclude that fibulin-2 is a driver of malignant progression in lung adenocarcinoma and plays an unexpected role in collagen cross-linking and tumor cell adherence to collagen.
Fibulin-2 is essential for angiotensin II-induced transforming growth factor-beta-mediated cardiac hypertrophy via enhanced TGF-beta (zeige TGFB1 ELISA Kits) activation.
absence of fibulin-2 results in decreased up-regulation of TGF-beta (zeige TGFB1 ELISA Kits) signaling after MI and protects against ventricular dysfunction.
Fibulin-2 and fibulin-5 (zeige FBLN5 ELISA Kits) cooperatively function to form the internal elastic lamina during postnatal development by directing the assembly of elastic fibers, and are responsible for maintenance of the adult vessel wall after injury
short arm region of laminin-5 gamma2 chain: structure, mechanism of processing and binding to heparin, nidogen-1 (zeige NID1 ELISA Kits), fibulin-1 (zeige FBLN1 ELISA Kits) and fibulin-2
This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified.