Fem-1 Homolog B (C. Elegans) Proteine (FEM1B)

Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit.

alle Proteine anzeigen Gen GeneID UniProt
Human FEM1B FEM1B 10116 Q9UK73
Ratte FEM1B FEM1B 315745 P0C6P7
Maus FEM1B FEM1B 14155 Q9Z2G0
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,813.33
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Weitere Proteine zu Fem-1 Homolog B (C. Elegans) (FEM1B) Interaktionspartnern

Human Fem-1 Homolog B (C. Elegans) (FEM1B) Interaktionspartner

  1. FEM1 proteins are ancient regulators of Stem-Loop Binding Protein (zeige SLBP Proteine).

  2. These findings have implications for understanding the cellular functions of Fem1b, and the regulation of Gli1 (zeige GLI1 Proteine) oncoprotein activity.

  3. the proapoptotic protein Fem1b is downregulated by the proteasome in malignant colon cancer cells and mediates proteasome inhibitor-induced apoptosis of these cells

  4. This study presents evidence suggesting a role for FEM1A (zeige FEM1A Proteine) and FEM1B in the pathogenesis of polycystic ovary syndrome. Only FEM1B variants were associated with insulin (zeige INS Proteine)-related traits in PCOS women.

  5. FEM1B is required for Rad9 (zeige RAD9A Proteine) recruitment and CHK1 (zeige CHEK1 Proteine) activation in response to replication stress.

Mouse (Murine) Fem-1 Homolog B (C. Elegans) (FEM1B) Interaktionspartner

  1. Fem1b is a binding partner of Ankrd37, and their interaction resulted in Ankrd37 degradation through the ubiquitin-mediated proteolysis pathway.

  2. Increased Fem1b is associated with intestinal neoplasia.

  3. neither FEM1B nor PHTF1 (zeige PHTF1 Proteine) are directly implicated in apoptosis in testis tissue

  4. Fem1b is implicated in pancreatic islet function and insulin (zeige INS Proteine) secretion

  5. Fem1b may have a conserved role in the generation of sexual dimorphism through its interaction with Nkx3.1 (zeige NKX3-1 Proteine) in the developing prostate gland

Fem-1 Homolog B (C. Elegans) (FEM1B) Protein Überblick

Protein Überblick

Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet (By similarity). Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1 (By similarity).

Genbezeichner und Symbole assoziert mit FEM1B

  • fem-1 homolog B (FEM1B)
  • fem-1 homolog B (Fem1b)
  • protein fem-1 homolog B (LOC413692)
  • fem-1 homolog B L homeolog (fem1b.L)
  • fem-1 homolog b (C. elegans) (fem1b)
  • feminization 1 homolog b (C. elegans) (Fem1b)
  • F1A-ALPHA Protein
  • F1AA Protein
  • FEM1-beta Protein
  • FEM1B Protein
  • mKIAA0396 Protein

Bezeichner auf Proteinebene für FEM1B

FEM-1-like death receptor binding protein , fem-1-like death receptor-binding protein alpha , fem-1-like in apoptotic pathway protein alpha , protein fem-1 homolog B , FEM1-beta , feminization 1 homolog b , feminization-1 , fem-1 homolog b (C. elegans) , F1A-alpha , mt-Fem

GENE ID SPEZIES
10116 Homo sapiens
315745 Rattus norvegicus
413692 Apis mellifera
444111 Xenopus laevis
467716 Pan troglodytes
478352 Canis lupus familiaris
540252 Bos taurus
567119 Danio rerio
693955 Macaca mulatta
100052688 Equus caballus
100344502 Oryctolagus cuniculus
100589391 Nomascus leucogenys
415559 Gallus gallus
14155 Mus musculus
100733293 Cavia porcellus
100158096 Sus scrofa
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