Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) Proteine (FCGR2A)

FCGR2A encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. Zusätzlich bieten wir Ihnen Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) Antikörper (197) und Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) Kits (19) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
FCGR2A 2212 P12318
FCGR2A    
FCGR2A 450194  
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Top Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) Proteine auf antikoerper-online.de

Showing 10 out of 36 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
$7,493.38
Details
Human Cells Human His tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$382.80
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CHO Cells Human His tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$382.80
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Baculovirus infected Insect Cells Human His tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$382.80
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Human Cells Rhesusaffen His tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$437.80
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Human Cells Cynomolgus AVI tag,His tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$437.80
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Human Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$280.50
Details
HEK-293 Cells Human His tag 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$308.00
Details
Human Cells Cynomolgus His tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$437.80
Details

FCGR2A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , ,
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Cynomolgus
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Chimpanzee

Am meisten referenzierte Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) Proteine

  1. Human FCGR2A Protein expressed in Human Cells - ABIN2002712 : Stuart, Simister, Clarkson, Kacinski, Shapiro, Mellman: Human IgG Fc receptor (hFcRII, CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium. in The EMBO journal 1990 (PubMed)
    Show all 3 Pubmed References

Weitere Proteine zu Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) Interaktionspartnern

Human Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) Interaktionspartner

  1. The results demonstrate that CD32 expression is a marker of CD4+ T cell activation in HIV+ individuals.

  2. this study shows that genetic variation of human neutrophil Fcgamma receptors and SIRPalpha in antibody-dependent cellular cytotoxicity towards cancer cells

  3. this study shows that FCGR genetic polymorphism affects antibody responses to GARP in patients with breast cancer

  4. Data indicate that the Fc gamma receptor FCgammaRIIA polymorphisms did not significantly influence response to rituximab in immune thrombocytopenic purpura (ITP).

  5. Results showed significantly higher frequency of FC gamma receptor FCGR3A-158V allele in patients with immune thrombocytopenia (ITP) compared with control subjects, but not significant differences in the genotype distribution or allele frequencies for FC gamma receptor FCGR2A-131H/R between patients and controls.

  6. Differently oxidized isolated subspecies can lead both to stronger as well as weaker binding and activation of the histidine variant of Fc fragment of IgG receptor IIa (FcgammaRIIa).

  7. CRP bound to surface CD32 (also known as FcgammaRII) on myeloma cells, which activated a pathway mediated by the kinase p38 MAPK and the transcription factor Twist that enhanced the cells' secretion of osteolytic cytokines.

  8. FCGR2A single nucleotide polymorphism confers susceptibility to idiopathic nephrotic syndrome

  9. alphaIIb beta3 antagonist TMV-7/trimucrin prevents thrombosis with causing Fc receptor gamma-chain IIa-mediated thrombocytopenia.

  10. The expression levels of human FcgammaRIIB but not FcgammaRIIA were negatively correlated with serum levels of IgE in human asthma patients.

  11. When higher-affinity genotypes for FCGR2A, FCGR3A, and FCGR2C were considered together, they were associated with significantly increased tumor shrinkage and prolonged survival in response to HD-IL2... this is the first study to show associations of FCGR genotypes with outcome following HD-IL2 treatment

  12. FcgammaRIIA and FcgammaRIIB both demonstrated increased methylation levels in Kawasaki disease (KD) patients that underwent IVIG treatment. FcgammaRIIA expression influenced the IVIG treatment response of KD patients. The FcgammaRIIA/IIB mRNA expression ratio was greater in KD patients with coronary artery lesion formation.

  13. FCGR2A rs1801274 G-allele confers susceptibility to Kawasaki disease and Ulcerative colitis

  14. farletuzumab has enhanced binding to FCGR3A-158V high-affinity receptor and has an enhanced clinical outcome in ovarian cancer patients with low baseline CA125 levels and at least 1 high-affinity allele of FCGR2A or FCGR3A

  15. inhibition of Abl/Src with bosutinib reduced FcgammaRIIA-mediated glomerular neutrophil accumulation and renal injury in experimental, crescentic anti-GBM nephritis.

  16. The present study demonstrates that p.His167Arg, a KD-associated FCGR2A variant, acts as a susceptibility gene in males only. Overall, the gender differences associated with FCGR2A in KD provide a new insight into KD susceptibility.

  17. Data indicate a mechanism in which Toll-like receptors TLR7/8 signaling, through shedding of FcgRIIA, shifts neutrophil function from phagocytosis to a programmed necrosis pathway, neutrophil extracellular trap formation (NETosis).

  18. Gene copy number variation (CNV) of the PKLR, FCGR2A, FCGR2C, and FCGR3 genes is associated with malaria severity, and our results provide evidence for a role of CNV in host responses to malaria.

  19. This study demonstrated that no association between FCGR2A polymorphisms in Guillain-Barre Syndrome in a Brazilian population.

  20. FCGR3A V and FCGR2A R allele carriers show better responsiveness to anti-TNF-alpha therapy--{REVIEW}

Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) Protein Überblick

Protein Überblick

This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit FCGR2A

  • Fc fragment of IgG receptor IIa (FCGR2A)
  • CD32 Protein
  • CD32a Protein
  • CDw32 Protein
  • FCG2 Protein
  • FcGR Protein
  • FCGR2 Protein
  • FCGR2A1 Protein
  • IGFR2 Protein

Bezeichner auf Proteinebene für FCGR2A

Immunoglobulin G Fc receptor II , fc-gamma RII-a , fc-gamma-RIIa , fcRII-a , igG Fc receptor II-a , low affinity immunoglobulin gamma Fc region receptor II-a , Fc fragment of IgG, low affinity IIa, receptor for (CD32) , Fc gamma receptor IIa

GENE ID SPEZIES
2212 Homo sapiens
450194 Pan troglodytes
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