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FCGR3A encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. Zusätzlich bieten wir Ihnen FCGR3A Proteine (33) und FCGR3A Kits (26) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal FCGR3A Primary Antibody für FACS - ABIN4896175
Markel, Seidman, Besser, Zabari, Ortenberg, Shapira, Treves, Loewenthal, Orenstein, Nagler, Schachter: Natural killer lysis receptor (NKLR)/NKLR-ligand matching as a novel approach for enhancing anti-tumor activity of allogeneic NK cells. in PLoS ONE 2009
Human Monoclonal FCGR3A Primary Antibody für FACS - ABIN4896166
Hartl, Krauss-Etschmann, Koller, Hordijk, Kuijpers, Hoffmann, Hector, Eber, Marcos, Bittmann, Eickelberg, Griese, Roos: Infiltrated neutrophils acquire novel chemokine receptor expression and chemokine responsiveness in chronic inflammatory lung diseases. in Journal of immunology (Baltimore, Md. : 1950) 2008
Memory-like differentiation resulted in enhanced IFN-gamma (zeige IFNG Antikörper) production triggered by leukemia targets or FcgammaRIIIa ligation within licensed NK cells, which exhibited the highest functionality of the NK cell subsets interrogated.
We developed a semi-mechanistic model including a target-mediated elimination component that accurately described rituximab PK in patients with CLL. This allowed us to show for the first time an influence of a baseline count of target antigen and the FCGR3A-158V/F polymorphism on rituximab target-mediated elimination.
When higher-affinity genotypes for FCGR2A (zeige FCGR2A Antikörper), FCGR3A (zeige CD16 Antikörper), and FCGR2C were considered together, they were associated with significantly increased tumor shrinkage and prolonged survival in response to HD-IL2 (zeige IL2 Antikörper)... this is the first study to show associations of FCGR genotypes with outcome following HD-IL2 (zeige IL2 Antikörper) treatment
FCGR3A (zeige CD16 Antikörper)-V158F polymorphism could be a specific marker for response to anti-TNFalpha (zeige TNF Antikörper) therapy in psoriasis patients.
The FCGR3A V allele correlated with the occurrence of late-onset neutropenia following rituximab treatment in patients with rheumatic diseases
farletuzumab has enhanced binding to FCGR3A-158V high-affinity receptor and has an enhanced clinical outcome in ovarian cancer patients with low baseline CA125 levels and at least 1 high-affinity allele of FCGR2A or FCGR3A
CXCR7 (zeige CXCR7 Antikörper) mediates CD14 (zeige NDUFA2 Antikörper)(+)CD16 (zeige CD16 Antikörper)(+) monocyte transmigration across the blood brain barrier, and is a potential therapeutic target for neuro AIDS.
KIR/HLA-C complex and CD16A (48H/R/L,158V/F) gene polymorphisms in 52 colorectal cancer patients and 61 local healthy controls, are reported..
These data suggest a role for FcgammaRIIIa-pSyk cosignaling in modulating NA-TLR responses in human CD4 (zeige CD4 Antikörper)(+) T cells by affecting the amounts and cellular distribution. These events are important for understanding of autoimmune pathology.
This study demonstrated that no association between FCGR3A polymorphisms in Guillain-Barre Syndrome in a Brazilian population.
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, Fc fragment of IgG, low affinity III, receptor for (CD16)
, Fc gamma receptor III-A
, Fc-gamma RIII-alpha
, Fc-gamma RIIIa
, Fc-gamma receptor III-2 (CD 16)
, Fc-gamma receptor IIIb (CD16)
, fc-gamma RIII
, igG Fc receptor III-2
, immunoglobulin G Fc receptor III
, low affinity immunoglobulin gamma Fc region receptor III-A
, neutrophil-specific antigen NA
, Fc fragment of IgG intermediate affinity IV receptor
, Fc fragment of IgG, low affinity IIIa, receptor for (CD16)
, transmembrane receptor FcgammaRIII-X