Fas Apoptotic Inhibitory Molecule (FAIM) ELISA Kits

The protein encoded by FAIM protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation.

list all ELISA KIts Gen GeneID UniProt
Anti-Human FAIM FAIM 55179 Q9NVQ4
Anti-Ratte FAIM FAIM 140930 Q8R5H8
Anti-Maus FAIM FAIM 23873 Q9WUD8
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
Details

Weitere ELISA Kits für FAIM Interaktionspartner

Human Fas Apoptotic Inhibitory Molecule (FAIM) Interaktionspartner

  1. the anti-apoptotic effect of SRT1720 was mitigated by FAIM knockdown with a small interfering RNA-targeted FAIM. These results indicated that pretreatment with SRT1720 improves survival of aged hMSCs, and enhances their therapeutic efficacy for rat myocardial infarction (MI).

  2. subcellular fractionation experiments revealed that, in contrast to FAIM-S and FAIM-L, FAIM-S_2a and FAIM-L_2a are able to localize to the nucleus, where they may have additional functions. In summary, here we report on two novel FAIM isoforms that may have relevant roles in the physiology and pathology of the nervous system

  3. Data indicate that FAIM is a novel regulator of insulin (zeige INS ELISA Kits) signalling and plays an essential role in energy homoeostasis.

  4. FAIM modulates IGF-1 (zeige IGF1 ELISA Kits)-induced Akt (zeige AKT1 ELISA Kits) activation and IRF4 (zeige IRF4 ELISA Kits) expression and has a role in multiple myeloma cell survival

  5. FAIM (1-90) was crystallized and diffracted to a resolution of 2.5 A; the crystal belonged to space group P3(1), with unit-cell parameters a=b=58.02, c=71.11 A, alpha=beta=90, gamma=120 degrees.

  6. Human keratinocytes were transfected with either Flip, Faim, or Lifeguard (LFG). Our results suggest that heterotopic expression of antiapoptotic proteins can induce the resistance of keratinocytes to a major mechanism of rejection.

  7. Expression of the long form of Fas apoptotic inhibitory molecule (FAIML) results in the protection of neurons from the cytotoxic actions of death ligands.

  8. FAIM acts to specifically enhance CD40 (zeige CD40 ELISA Kits) signaling for NF-kappaB (zeige NFKB1 ELISA Kits) activation, IRF-4 (zeige IRF4 ELISA Kits) expression, and BCL-6 (zeige BCL6 ELISA Kits) down-regulation in vitro, but has no effect on its own

Mouse (Murine) Fas Apoptotic Inhibitory Molecule (FAIM) Interaktionspartner

  1. The neuron-specific form of FAIM protein (FAIM-L) is a death receptor antagonist that stabilizes XIAP (zeige XIAP ELISA Kits) protein levels, thus preventing death receptor-induced neuronal apoptosis. Here we show that FAIM-L modulates synaptic transmission, prevents chemical-LTD induction in hippocampal neurons, and thwarts axon degeneration after nerve growth factor (NGF) withdrawal.

  2. Data indicate that FAIM is a novel regulator of insulin (zeige INS ELISA Kits) signalling and plays an essential role in energy homoeostasis.

  3. defined a TCR-induced FAIM/Akt (zeige AKT1 ELISA Kits)/Nur77 (zeige NR4A1 ELISA Kits) signaling axis that is critical for modulating the apoptosis of developing thymocytes

  4. The NMR solution structure of the C-terminal domain of murine FAIM is solved in isolation and revealed to be a novel protein fold, a noninterleaved seven-stranded beta-sandwich.

  5. FAIM plays a novel role in modulating Fas (zeige FAS ELISA Kits)-mediated apoptosis and acts through influencing the expression of c-FLIP (zeige CFLAR ELISA Kits) and regulating the physical binding of caspase-8 (zeige CASP8 ELISA Kits) to Fas (zeige FAS ELISA Kits).

  6. FAIM is expressed in germinal center B cells, enhances interferon (zeige IFNA ELISA Kits) regulatory factor (IRF)4 (zeige IRF4 ELISA Kits) expression, and is in turn positively regulated through IRF4 (zeige IRF4 ELISA Kits) in a positive reinforcing (i.e., feed-forward) system.

FAIM Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene protects against death receptor-triggered apoptosis and regulates B-cell signaling and differentiation. Several transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit FAIM

  • Fas apoptotic inhibitory molecule (FAIM) Antikörper
  • Fas apoptotic inhibitory molecule (Faim) Antikörper
  • Fas apoptotic inhibitory molecule (faim) Antikörper
  • Fas apoptotic inhibitory molecule L homeolog (faim.L) Antikörper
  • Fas apoptotic inhibitory molecule (Tsp_00038) Antikörper
  • faim Antikörper
  • FAIM1 Antikörper

Bezeichner auf Proteinebene für FAIM

fas apoptotic inhibitory molecule 1 , Fas apoptotic inhibitory molecule , Fas apoptosis inhibitory molecule 1

GENE ID SPEZIES
55179 Homo sapiens
460729 Pan troglodytes
716216 Macaca mulatta
140930 Rattus norvegicus
616795 Bos taurus
496608 Xenopus (Silurana) tropicalis
485687 Canis lupus familiaris
424270 Gallus gallus
23873 Mus musculus
734582 Xenopus laevis
10901294 Trichinella spiralis
100568454 Sus scrofa
100727709 Cavia porcellus
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