anti-Fanconi Anemia Complementation Group M (FANCM) Antikörper

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). Zusätzlich bieten wir Ihnen FANCM Kits (4) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FANCM 57697 Q8IYD8
FANCM 104806 Q8BGE5
FANCM    
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Top anti-FANCM Antikörper auf antikoerper-online.de

Showing 10 out of 83 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$247.24
Details
Human Ziege Unkonjugiert ELISA, WB   0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Ziege Unkonjugiert ELISA   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$373.75
Details
Human Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Kaninchen Unkonjugiert IF Immunofluorescence analysis of A549 cells using FANCM antibody. 120 μL Anmelden zum Anzeigen 12 bis 14 Tage
$251.90
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western blot analysis FANCM using 293 whole cell lysates Western blot analysis of extracts from mouse spleen, using FANCM Antibody. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Maus Unkonjugiert ICC, IF, IP, WB   0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$345.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of HeLa and NCI-H460 cells, using FANCM antibody. Immunofluorescence analysis of A549 cell using FANCM antibody. 100 μL Anmelden zum Anzeigen 16 Days
$334.77
Details
Human Kaninchen Unkonjugiert IF/ICC, WB Immunofluorescence analysis of A549 cells using FANCM antibody (ABIN5974940). 100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$426.40
Details
Human Kaninchen Unkonjugiert IC, IF, WB   200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details

Am meisten referenzierte anti-FANCM Antikörper

  1. Human Monoclonal FANCM Primary Antibody für ICC, IF - ABIN4310526 : Fouquet, Pawlikowska, Caburet, Guigon, Mäkinen, Tanner, Hietala, Urbanska, Bellutti, Legois, Bessieres, Gougeon, Benachi, Livera, Rosselli, Veitia, Misrahi: A homozygousFANCMmutation underlies a familial case of non-syndromic primary ovarian insufficiency. in eLife 2018 (PubMed)

  2. Human Polyclonal FANCM Primary Antibody für ELISA - ABIN4271349 : Barroso, Pita, Arias, Menendez, Zamora, Blanco, Benitez, Ribas: The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features. in Breast cancer research and treatment 2009 (PubMed)

Weitere Antikörper gegen FANCM Interaktionspartner

Human Fanconi Anemia Complementation Group M (FANCM) Interaktionspartner

  1. FANCM expression is a prognostic factor for overall survival in luminal B breast cancer in Chinese patients.

  2. Loss-of-function mutations in FANCM cause a cancer predisposition syndrome clinically distinct from bona fide FA. Care should be taken with chemotherapy and radiation treatments in these patients due to expected acute toxicity.

  3. Our data indicate that biallelic FANCM mutations do not cause classical FA, providing proof that FANCM is not a canonical FA gene. FANCM is a breast cancer-predisposing gene. Mutation testing of FANCM might be considered for individuals with the above-described clinical features.

  4. Two FANCM truncating mutations, the c.1432C>T (p.Arg478Ter) and c.1972C>T (p.Arg658Ter), were identified in two Male Breast Cancer cases (0.7%). When specifically considering cases at increased genetic risk for BC, FANCM mutation frequency raises up to 1%. Rare FANCM truncating mutations, other than c.5101C>T and c.5791C>T, may have a role in MBC (zeige DOCK2 Antikörper) susceptibility.

  5. Mutation in FANCM gene is associated with non-syndromic primary ovarian insufficiency.

  6. These results support the role of FANCM as a breast cancer susceptibility gene, particularly for triple-negative breast cancer.

  7. FANCM is actively recruited to the alternative lengthening of telomeres that are experiencing replication stress.

  8. we demonstrated that FANCM is a direct target of miR146a

  9. This case-control study included 2047 BRCA1 and BRCA2 (zeige BRCA2 Antikörper)-negative familial breast cancer cases and 2187 controls and revealed an association of FANCM mutations with breast cancer. More pronounced associations were identified for early-onset (before age 51 years) breast cancer and triple-negative breast cancer.

  10. FANCM c.5101C > T nonsense mutation carriers have a reduced breast cancer survival but postoperative radiotherapy may diminish this survival disadvantage.

Mouse (Murine) Fanconi Anemia Complementation Group M (FANCM) Interaktionspartner

  1. Fancm(Delta2/Delta2) mice also showed unique features atypical for Fanconi anemia (zeige PALB2 Antikörper) mice, including underrepresentation of female Fancm(Delta2/Delta2) mice and decreased overall and tumor-free survival.

FANCM Antigen-Profil

Protein Überblick

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M.

Genbezeichner und Symbole assoziert mit FANCM

  • Fanconi anemia complementation group M (FANCM) Antikörper
  • hypothetical protein (PGTG_17854) Antikörper
  • Fanconi anemia, complementation group M (Fancm) Antikörper
  • AI427100 Antikörper
  • C730036B14Rik Antikörper
  • D12Ertd364e Antikörper
  • FAAP250 Antikörper
  • KIAA1596 Antikörper

Bezeichner auf Proteinebene für FANCM

Fanconi anemia complementation group M , fanconi anemia complementation group M , ATP-dependent RNA helicase FANCM , Fanconi anemia group M protein , fanconi anemia-associated polypeptide of 250 kDa , protein Hef ortholog , Fanconi anemia group M protein homolog

GENE ID SPEZIES
513626 Bos taurus
10531976 Puccinia graminis f. sp. tritici CRL 75-36-700-3
57697 Homo sapiens
104806 Mus musculus
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