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The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). Zusätzlich bieten wir Ihnen Fanconi Anemia Complementation Group G Proteine (3) und Fanconi Anemia Complementation Group G Kits (2) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal FANCG Primary Antibody für IHC - ABIN966129
Liu, Lamerdin, Tucker, Zhou, Walter, Albala, Busch, Thompson: The human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cells. in Proceedings of the National Academy of Sciences of the United States of America 1997
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Human Polyclonal FANCG Primary Antibody für IHC - ABIN966130
Garcia-Higuera, Kuang, Näf, Wasik, DAndrea: Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex. in Molecular and cellular biology 1999
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Human Polyclonal FANCG Primary Antibody für WB - ABIN251005
Park, Ciccone, Beck, Hwang, Freie, Clapp, Lee: Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins. in The Journal of biological chemistry 2004
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Human Monoclonal FANCG Primary Antibody für IF, IP - ABIN560843
Hinz, Nham, Yamada, Tebbs, Salazar, Hinz, Mohrenweiser, Jones, Thompson: Four human FANCG polymorphic variants show normal biological function in hamster CHO cells. in Mutation research 2006
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Human Polyclonal FANCG Primary Antibody für ELISA, WB - ABIN449536
Tomida, Itaya, Shigechi, Unno, Uchida, Ikura, Masuda, Matsuda, Adachi, Kobayashi, Meetei, Maehara, Yamamoto, Kamiya, Matsuura, Matsuda, Ikura, Ishiai, Takata: A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair. in Nucleic acids research 2013
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Identification of the Xenopus laevis ortholog of human FANCG (xFANCG), its expression during development, and its molecular interactions with a partner protein, xFANCA
LOH may predominantly indicate copy number gains in FANCF (zeige FANCF Antikörper) and losses in FANCG and BRIP1 (zeige MRPL36 Antikörper). Integration of copy number data and gene expression proved difficult as the available sample sets did not overlap.
studied the impact of mutations on the function and structure of FANCG
Patients, homozygous for the FANCG founder mutation, present with severe cytopenia but progress to bone marrow failure at similar ages to other individuals affected with Fanconi anemia (zeige PALB2 Antikörper) of heterogeneous genotype.
founder haplotype analysis of FANCG for the Korean Fanconi anemia (zeige PALB2 Antikörper) population
A new role of FANCG in Homologous recombination repair of interstrand crosslinks through K63Ub-mediated interaction with the Rap80-BRCA1 complex.
FANCA (zeige FANCA Antikörper) and FANCG are the major Fanconi anemia (zeige PALB2 Antikörper) genes in the Korean population.
Areca nut extracts-induced miR (zeige MLXIP Antikörper)-23a was correlated with a reduced FANCG expression and DSB repair, which might contribute to ANE-associated human malignancies.
sites of interaction of FANCG with ERCC1 (zeige ERCC1 Antikörper), which is different from the region of ERCC1 (zeige ERCC1 Antikörper) that binds to XPF (zeige ERCC4 Antikörper)
Study of the molecular evolution of FA genes using database search methods such as PSI-BLAST suggested that FANCG may contain a known domain, and that this protein is a member of the family of tetratricopeptide repeat-containing proteins.
There is remarkably lage sequence variation in FANCG gene mutations and polymorphisms across ethnic and racial backgrounds found in the International Fanconi Anemia (zeige PALB2 Antikörper) Registry they include IVS8-2A>G, IVS11+1G>c, 1794_1803del10, and IVS3+1G>C.
Hematopoietic stem cells of Fancg-/- mice Impaired functionality and homing.
null mutations in Fanca (zeige FANCA Antikörper) or Fancg are fully epistatic
the FA pathway (FancG) is not involved in regulating the outcome of SHM (zeige CNTNAP1 Antikörper) in mammals and it appears dispensable for class switch recombination
Data show that Fancd2 (zeige FANCD2 Antikörper)(-/-) mice displayed a higher magnitude of chromosomal breakage and micronucleus formation than the wild-type or Fancg(-/-) mice.
Double-mutant Fancc (zeige FANCC Antikörper)(-/-);Fancg(-/-) mice develop spontaneous hematologic sequelae including bone marrow failure, acute myeloid leukemia (zeige BCL11A Antikörper), myelodysplasia and complex random chromosomal abnormalities that the single-mutant mice do not.
Mice deficient in Fancg were not anemic, but showed hypogonadism, impaired fertility, and hypersensitivity to mitomycin C
FANCG is required for efficient homologous recombination-mediated repair of at least some types of DNA double-strand breaks
Fancg deeficient mouse cells display normal telomere length, normal telomerase activity, and normal chromosome end-capping
a deletion mutation in the FANCG gene (c.637_643delTACCGCC) was present in 82% of Fanconi anemia (zeige PALB2 Antikörper) patients in the black populations of Southern Africa
Ataxia telangiectasia mutated (zeige ATM Antikörper) and Fanconi anemia (zeige PALB2 Antikörper) genes function in parallel and compensatory roles to maintain genomic integrity and cell viability.
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.
Fanconi anemia complementation group G variant 2
, DNA repair protein XRCC9
, Fanconi anemia group G protein
, X-ray repair complementing defective repair in Chinese hamster cells 9
, X-ray repair, complementing defective, in Chinese hamster, 9
, Fanconi anemia group G protein homolog