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When transfected into cell lines in which it is not expressed, suppresses cell growth. Zusätzlich bieten wir Ihnen FAM107A Antikörper (24) und FAM107A Kits (13) und viele weitere Produktgruppen zu diesem Protein an.
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This study has thus revealed a novel nuclear complex of F-actin, DRR1 and COMMD1 (zeige COMMD1 Proteine) that is involved in NF-kappaB (zeige NFKB1 Proteine) degradation and cell cycle suppression in neuroblastoma (zeige ARHGEF16 Proteine) cells.
Importance of FAM107A in lung carcinogenesis, although other than promoter hypermethylation mechanism of the gene decreased expression.
Results found that DRR expression leads to elevated AKT (zeige AKT1 Proteine) activation by recruiting AKT (zeige AKT1 Proteine) to focal adhesios in a manner dependent on SRC (zeige SRC Proteine)-family kinases (SFKs) and cell adhesion.
DRR1 protein is expressed in normal cells, particularly in the nervous system during embryogenesis, is involved in neuronal cell survival, and is downregulated during neuroblastoma (zeige ARHGEF16 Proteine) carcinogenesis.
Expression of the down-regulated in renal cell carcinoma (zeige MOK Proteine) gene (DRR1) gene at 3p14.2 was lost in 7 and down regulated in 2 "chr3+" tumours.
TU3A is epigenetically inactivated in human cancer
Endogenous DRR1 localizes to some, but not all, synapses, with preference for the presynaptic region. Enhancement of DRR1 expression reduced spine density, diminished the probability of synaptic glutamate (zeige GRIN1 Proteine) release, and altered cognitive performance.
When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role in tumor development.
uncharacterized protein LOC494764
, down-regulated in renal cell carcinoma 1
, family with sequence similarity 107 member A transcript
, protein FAM107A
, downregulated in renal cell carcinoma