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The protein encoded by FKBPL has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Zusätzlich bieten wir Ihnen FK506 Binding Protein Like Antikörper (70) und FK506 Binding Protein Like Kits (19) und viele weitere Produktgruppen zu diesem Protein an.
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This study identified two low-frequency nonsynonymous variants at FKBPL (rs200847762, OR = 0.34, 95% CI = 0.20-0.57, P = 4.31 x 10-5) and ARPC1B (zeige ARPC1B Proteine) (rs1045012, OR = 0.56, 95% CI = 0.43-0.74, P = 4.30 x 10-5) associated with breast cancer risk.
The data suggests a role for FKBPL as a prognostic factor for BCSS, with the potential to be routinely evaluated within the clinic.
WISp39 preferentially interacts with phosphorylated Coronin 1B (zeige CORO1B Proteine), allowing it to complex with Slingshot phosphatase to dephosphorylate and activate Cofilin (zeige CFL1 Proteine).
FKBPL is an important regulator of developmental and pathological angiogenesis.
high levels of FKBPL and RBCK1 (zeige RBCK1 Proteine) correlated with increased patient survival, whereas high RBCK1 (zeige RBCK1 Proteine) predicted for a poor response to tamoxifen.
FKBPL and and its peptide derivative, AD-01 regulate expression of CD44 (zeige CD44 Proteine).
Genome-wide association study of age-related macular degeneration identifies TNXB (zeige TNXB Proteine), FKBPL and NOTCH4 (zeige NOTCH4 Proteine) as candidate susceptibility genes.
Alterations in the gene for FKBPL in azoospermic patients.
Findings suggest that FKBPL may have prognostic value based on its impact on tumor proliferative capacity and sensitivity to endocrine therapies, which improve outcome.
Results demonstrate the importance of posttranslational stabilization of p21 protein (zeige NRAS Proteine) by WISp39 in regulating cellular p21 (zeige CDKN1A Proteine) activity.
Results demonstrate the importance of posttranslational stabilization of p21 protein (zeige NRAS Proteine) by WISp39 in regulating cellular p21 activity.
The protein encoded by this gene has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle.
FK506 binding protein like
, WAF-1/CIP1 stabilizing protein 39
, FK506-binding protein-like
, FK506-binding protein like
, immunophilin-like protein NG7