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The Fos gene family consists of 4 members FOSL1, and FOSL2. Zusätzlich bieten wir Ihnen FBJ Murine Osteosarcoma Viral Oncogene Homolog B Proteine (7) und FBJ Murine Osteosarcoma Viral Oncogene Homolog B Kits (5) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal FOSB Primary Antibody für FACS, WB - ABIN1882084
Li, Fu, Wang, Tie, Xing, Zhu, Sun, Wei, Zheng: MicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene in human hepatocellular carcinoma. in Hepatology (Baltimore, Md.) 2009
FOSB overexpression results in TNBC cell death, whereas inhibition of calcium signaling eliminates FOSB induction and blocks TP4-induced TNBC cell death
results shows the involvement of Spry2 (zeige SPRY2 Antikörper) in regulation of FosB and Runx2 (zeige RUNX2 Antikörper) genes, MAPK (zeige MAPK1 Antikörper) signaling and proliferation of mesenchymal stem cells.
the mechanism underlying redox-regulation of AP-1 Fos/Jun transcription factors and provide structural insight for therapeutic interventions targeting AP-1 proteins.
The NFATc3 (zeige NFATC3 Antikörper) first induced the expression of its interaction partner FosB before forming the heterodimeric NFATc3 (zeige NFATC3 Antikörper)-FosB transcription factor complex, which bound the proximal AP-1 site in the TF gene promoter and activated TF expression.
FosB expression in the prefrontal cortex and hippocampus of the cocaine addicted and depression patients
FOSB is a highly sensitive and diagnostically useful marker for pseudomyogenic hemangioendothelioma.
our findings show that DeltaFosB increases the expression of MMP-9 (zeige MMP9 Antikörper) and exhibits a significantly high survival and proliferation in MCF-7 cells.
Diffuse and strong FOSB expression was specific for pseudomyogenic hemangioendothelioma in the current series and FOSB immunohistochemistry is an effective tool for differentiating between PHE and its histological mimics.
Our results using a number of approaches, such as promoter reporter assay, FosB knock down and Chip assay, suggest that the expression of miR (zeige MLXIP Antikörper)-22 is regulated transcriptionally by FosB.
These results suggest that SETDB1 (zeige SETDB1 Antikörper)- mediated FosB expression is a common molecular phenomenon, and might be a novel pathway responsible for the increase in cell proliferation that frequently occurs during anticancer drug therapy.
study provides key insights into functional domains regulated by FosB in the hippocampus, emphasizing remarkably different programs of gene regulation under physiological and pathological conditions
These findings suggest that GosB may regulate mammary epithelial cells milk fat synthesis and apoptosis via PPARgamma (zeige PPARG Antikörper) in mouse mammary glands.
propose that chronic suppression of calbindin (zeige CALB1 Antikörper) by DeltaFosB is one mechanism through which intermittent seizures drive persistent cognitive deficits in conditions accompanied by recurrent seizures
Both CREB (zeige CREB1 Antikörper) and deltaFosB play a role in the induction of this behavioural sensitization.
Study investigated effects of chronic variable mild stress (CVMS) in non-injected, vehicle and imipramine-treated KO mice vs. wildtype (WT) counterparts and mapped the CVMS-related FosB response in 18 brain areas; found that PACAP (zeige ADCYAP1 Antikörper) deficiency affects neuronal reactivity in a brain area-specific manner in stress centers
abnormal regulation of MSK1 (zeige RPS6KA5 Antikörper) contributes to the development of L-DOPA-induced dyskinesia and to the concomitant increase in striatal FosB, which may occur via increased histone H3 (zeige HIST3H3 Antikörper) phosphorylation at the fosB promoter
The most highly stereotypic mice showed the most elevated FosB/DeltaFosB activity in the nucleus accumbens
FosB/DeltaFosB immunoreactivity was transiently increased in hippocampus and parahippocampal cortices by 6-Hz corneal stimulation. FosB induction was primarily localized in pyramidal neurons.
Histone methylation or acetylation at the Fosb locus in nucleus accumbens, was sufficient to control drug- and stress-evoked behavioral responses.
Findings demonstrate that, under excitotoxicity, Fosb products contribute to a neuroinflammatory response in the hippocampus through regulation of microglial C5ar1 (zeige C5AR1 Antikörper) and C5ar2 expression
The Fos gene family consists of 4 members FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
FBJ murine osteosarcoma viral oncogene homolog B
, protein fosB
, G0/G1 switch regulatory protein 3
, activator protein 1
, FBJ osteosarcoma viral oncogene isoform deltaFosb-2