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member of the mammalian Fat family; similar to a Drosophila tumor suppressor gene. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.
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For Fat3, the Kif5 (zeige KIF5A Antikörper)-ID is regulated by alternative splicing, and the timecourse of splicing suggests that the distribution of Fat3 may switch between early and later stages of retinal development. In contrast, P75NTR (zeige NGFR Antikörper) binding to Kif5B (zeige KIF5B Antikörper) is enhanced by tyrosine phosphorylation and thus has the potential to be dynamically regulated on a more rapid time scale
Fat3 functions cell-autonomously and is able to influence the cytoskeleton directly through its intracellular domain, which can bind and localize Ena/VASP family actin regulators.
Data find that during mouse development, Fat3 and Fat4 (zeige FAT4 Antikörper) synergize to drive vertebral arch fusion at the dorsal midline during caudal (zeige CAD Antikörper) vertebra morphogenesis.
This study demonistrated that fat3 mutation in thr (zeige TRH Antikörper) mice caused amacrine cell migration and retina development.
member of the mammalian Fat family; similar to a Drosophila tumor suppressor gene
FAT tumor suppressor homolog 3
, cadherin family member 15
, cadherin-related family member 10
, protocadherin Fat 3
, Fta3 protein
, protocadherin Fat3