F-Box and Leucine-Rich Repeat Protein 18 Proteine (FBXL18)

Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. Zusätzlich bieten wir Ihnen FBXL18 Antikörper (27) und FBXL18 Kits (13) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
FBXL18 80028 Q96ME1
Maus FBXL18 FBXL18 231863  
Ratte FBXL18 FBXL18 678726  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top FBXL18 Proteine auf antikoerper-online.de

Showing 3 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,984.89
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
Details

FBXL18 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,

Weitere Proteine zu F-Box and Leucine-Rich Repeat Protein 18 (FBXL18) Interaktionspartnern

Human F-Box and Leucine-Rich Repeat Protein 18 (FBXL18) Interaktionspartner

  1. Study showed that LRRK2 phosphorylation is required for LRRK2 to bind to Fbxl18, and that this interaction is important for regulating the amount of LRRK2 via ubiquitination of LRRK2 by the SCFFbxl18 ubiquitin ligase and subsequent proteasomal degradation of LRRK2. We also show that LRRK2 can induce caspase 8 mediated cell death and that the degradation of LRRK2 mediated by Fbxl18 can prevent LRRK2-mediated toxicity.

  2. FBXL18 plays an oncogenic role through promoting lysine 63-linked ubiquitination of Akt (zeige AKT1 Proteine) in glioma.

  3. Fbxl18 regulates apoptosis by mediating ubiquitin-dependent proteasomal degradation of the pro-apoptotic protein Fbxl7 (zeige FBXL7 Proteine) that may impact cellular processes involved in cell cycle progression.

Mouse (Murine) F-Box and Leucine-Rich Repeat Protein 18 (FBXL18) Interaktionspartner

  1. Study showed that LRRK2 phosphorylation is required for LRRK2 to bind to Fbxl18, and that this interaction is important for regulating the amount of LRRK2 via ubiquitination of LRRK2 by the SCFFbxl18 ubiquitin ligase and subsequent proteasomal degradation of LRRK2. We also show that LRRK2 can induce caspase 8 mediated cell death and that the degradation of LRRK2 mediated by Fbxl18 can prevent LRRK2-mediated toxicity.

FBXL18 Protein Überblick

Protein Überblick

Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1\\\\; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004

Genbezeichner und Symbole assoziert mit FBXL18

  • F-box and leucine rich repeat protein 18 (FBXL18)
  • F-box and leucine-rich repeat protein 18 (Fbxl18)
  • F-box and leucine-rich repeat protein 18 (fbxl18)
  • F-box and leucine rich repeat protein 18 (Fbxl18)
  • AI427077 Protein
  • B130019G13Rik Protein
  • C330021B20Rik Protein
  • Fbl18 Protein
  • FBXL18 Protein
  • zgc:114102 Protein

Bezeichner auf Proteinebene für FBXL18

F-box/LRR-repeat protein 18 , F-box and leucine-rich repeat protein 18 , f-box/LRR-repeat protein 18-like

GENE ID SPEZIES
80028 Homo sapiens
231863 Mus musculus
416484 Gallus gallus
463246 Pan troglodytes
489881 Canis lupus familiaris
570298 Danio rerio
678726 Rattus norvegicus
789838 Bos taurus
100230780 Taeniopygia guttata
100341656 Oryctolagus cuniculus
100438128 Pongo abelii
100492578 Xenopus (Silurana) tropicalis
100540295 Meleagris gallopavo
100597886 Nomascus leucogenys
101108448 Ovis aries
100728425 Cavia porcellus
Ausgewählte Anbieter für FBXL18 Proteine (FBXL18)
Haben Sie etwas anderes gesucht?