Eukaryotic Translation Initiation Factor 1A, X-Linked Proteine (EIF1AX)

EIF1AX encodes an essential eukaryotic translation initiation factor. Zusätzlich bieten wir Ihnen EIF1AX Antikörper (28) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte EIF1AX EIF1AX 302697  
EIF1AX 66235 Q8BMJ3
EIF1AX 1964 P47813
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Top EIF1AX Proteine auf antikoerper-online.de

Showing 9 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
Details
Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$522.50
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Anmelden zum Anzeigen 11 Days
$291.50
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$340.00
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Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$400.00
Details
Escherichia coli (E. coli) Human His tag   1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$3,655.38
Details
Escherichia coli (E. coli) Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$300.00
Details
Human Unkonjugiert   1 mg Anmelden zum Anzeigen 6 Days
$4,125.00
Details

EIF1AX Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human ,
,

Weitere Proteine zu Eukaryotic Translation Initiation Factor 1A, X-Linked (EIF1AX) Interaktionspartnern

Human Eukaryotic Translation Initiation Factor 1A, X-Linked (EIF1AX) Interaktionspartner

  1. Its mutation is found in patients with meningeal melanocytic tumor.

  2. Study identified a new RNA-induced silencing complex component, eIF1A, which directly interacts with the MID-domain of Ago2 and functions in DICER-independent miRNA biogenesis and miRNA-mediated RNA interference.

  3. EIF1AX alterations occurred infrequently in low-grade gliomas (1.4%), uterus endometrial carcinoma (1.25%), thyroid carcinoma (1%), and lung adenocarcinoma (0.4%).

  4. In this report we show that patients with uveal melanoma harbor mutation-specific chromosomal patterns in the tumor. These chromosomal patterns are characterized by different types of chromosomal anomalies, thus illustrating that distinct biological mechanisms underlie uveal melanoma pathogenesis.

  5. Coexpression of mutant NRAS and EIF1AX proteins promoted proliferation and clonogenic survival in LGSC cells, providing the first example of co-occurring, growth-promoting mutational events in ovarian cancer.

  6. Short 5'UTR mRNAs are enriched with TISU (translation initiator of short 5'UTR), a 12-nucleotide element directing efficient scanning-independent translation. This study demonstrate that TISU is particularly dependent on eukaryotic initiation factor 1A (eIF1A) which interacts with both RPS3 and RPS10e.

  7. Mutation in EIF1AX gene is associated with Uveal Melanoma.

  8. we find iris melanomas to be related genetically to choroidal and ciliary body melanomas, frequently harboring GNAQ, GNA11, and EIF1AX mutations.

  9. results indicate that the interactions between eIF1A and eIF5B are being continuously rearranged during translation initiation; presentation of a model how the dynamic eIF1A/eIF5B interaction network can promote remodeling of the translation initiation complexes, and the roles in the process played by intrinsically disordered protein segments

  10. Patients with uveal melanoma can be classified into 3 groups, of which EIF1AX-mutated tumors and tumors without BAP1, SF3B1, or EIF1AX mutations are associated with prolonged survival and low metastatic risk, SF3B1-mutated tumors are associated with late metastasis

  11. BAP1, SF3B1, and EIF1AX mutations occur during uveal melanoma tumor progression in an almost mutually exclusive manner and are associated with different levels of metastatic risk.

  12. We report here the occurrence of EIF1AX mutations not only in thyroid cancer, but also in benign thyroid nodules, and demonstrate that phenotypically these mutations are associated with the encapsulated follicular variant of papillary thyroid carcinoma and benign follicular-pattern nodules.

  13. The finding of this study suggested that an SF3B1 or EIF1AX mutation is present in a substantial subset of primary LMNs underscores that these tumors genetically resemble uveal melanoma and are different from cutaneous melanoma at the genetic level.

  14. Then, activated p38 further enhanced the docking of activating transcription factor 4 (ATF4) onto the CHOP (CCAAT/enhancer-binding protein homologous protein) promoter via eIF2alpha to enhance apoptosis

  15. The effect of an EIF1AX mutation is estimated to be a decreased odds of metastasis in uveal melanoma.

  16. the newly identified driver mutations in EIF1AX and SF3B1, specifically found in uveal melanomas with disomy 3, confirm and extend the established classification model of uveal melanoma.

  17. Coordinated movements of eukaryotic translation initiation factors eIF1, eIF1A, and eIF5 trigger phosphate release from eIF2 in response to start codon recognition by the ribosomal preinitiation complex

  18. eIF3j/HCR1 closely cooperates with the eIF3b/PRT1 RNA recognition motif and eIF1A on the ribosome to ensure proper formation of the scanning-arrested conformation required for stringent AUG recognition

  19. Remarkable conservation of translation initiation factors: IF1/eIF1A and IF2/eIF5B are universally distributed phylogenetic markers.

  20. Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm.

Cow (Bovine) Eukaryotic Translation Initiation Factor 1A, X-Linked (EIF1AX) Interaktionspartner

  1. molecular network including eIF1AX, RPS7, and 14-3-3gamma regulates protein translation and cell proliferation in BMECs.

EIF1AX Protein Überblick

Protein Überblick

This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA.

Genbezeichner und Symbole assoziert mit EIF1AX

  • eukaryotic translation initiation factor 1A, X-linked (Eif1ax)
  • eukaryotic translation initiation factor 1A, X-linked (EIF1AX)
  • eukaryotic translation initiation factor 1A, X-linked S homeolog (eif1ax.S)
  • eukaryotic translation initiation factor 1A, X-linked, a (eif1axa)
  • 1500010B24Rik Protein
  • AI426898 Protein
  • eif-1a Protein
  • eif-4c Protein
  • eif1a Protein
  • eif1ap1 Protein
  • eif1ax Protein
  • EIF1AY Protein
  • eif4c Protein
  • RGD1560198 Protein
  • zgc:101670 Protein

Bezeichner auf Proteinebene für EIF1AX

eukaryotic translation initiation factor 1A, X-chromosomal , eukaryotic translation initiation factor 1A, Y-linked , eIF-1A X isoform , eIF-4C , eukaryotic translation initiation factor 4C , Putative eukaryotic translation initiation factor 1A , eukaryotic translation initiation factor 1A, X chromosome , eukaryotic translation initiation factor 1A, X-linked S homeolog

GENE ID SPEZIES
302697 Rattus norvegicus
66235 Mus musculus
1964 Homo sapiens
444500 Xenopus laevis
450062 Danio rerio
100720954 Cavia porcellus
511189 Bos taurus
611715 Canis lupus familiaris
695456 Macaca mulatta
100270711 Ovis aries
100522912 Sus scrofa
Ausgewählte Anbieter für EIF1AX Proteine (EIF1AX)
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