Endo-beta-N-Acetylglucosaminidase Proteine (ENGASE)

ENGASE encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides. Zusätzlich bieten wir Ihnen ENGASE Antikörper (14) und ENGASE Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte ENGASE ENGASE 303702  
ENGASE 64772 Q8NFI3
ENGASE 217364 Q8BX80
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Top ENGASE Proteine auf antikoerper-online.de

Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,741.67
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 70 Days
$13,741.67
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$814.00
Details
Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$582.75
Details

ENGASE Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
,
Mouse (Murine)

Weitere Proteine zu Endo-beta-N-Acetylglucosaminidase (ENGASE) Interaktionspartnern

Human Endo-beta-N-Acetylglucosaminidase (ENGASE) Interaktionspartner

  1. In patients with autosomal dominant polycystic kidney disease, urinary NAGase was correlated with urinary ET-1 which was inversely associated with eGFR and positively correlated with total kidney volume.

  2. Serological N-acetyl-glucosaminidase, telomere length, and the UCP2-886G>A variant are independent risk factors for type 2 diabetes.

  3. As the generation of the bulk of fOS is unaffected by co-down regulation of Ngly1p and Engase1p, alternative quantitatively important mechanisms must underlie the liberation of these fOS from either LLO or glycoproteins during protein N-glycosylation.

  4. O-GlcNAcase expression is increased in erythrocytes from both individuals with pre-diabetes and individuals with less well-controlled diabetes.

  5. Data show that kinetic and X-ray crystallographic analyses of the binding modes with human/bacterial O-GlcNAcases identify some of these as competitive inhibitors.

  6. involved in processing of free oligosaccharides in the cytosol; identification of the gene encoding human cytosolic ENGase

  7. endo-beta-n-acetylglucosaminidase present in the synovial fluid of rheumatoid arthritis patients, may contribute to the depletion of glycosaminoglycans from cartilage allowing the invasion of synovial cells

  8. identification of O-GlcNAcase as a caspase-3 substrate with a novel caspase-3 cleavage site and provide insight about O-GlcNAcase regulation during apoptosis.

Mouse (Murine) Endo-beta-N-Acetylglucosaminidase (ENGASE) Interaktionspartner

  1. These observations strongly suggest that the Ngly1- or Ngly1/Engase-deficient mice could serve as a valuable animal model for studies related to the pathogenesis of the NGLY1-deficiency, and that cytoplasmic ENGase represents one of the potential therapeutic targets for this genetic disorder.

  2. ENGase efficiently hydrolyzes phosphorylated oligosaccharides that are larger than Man4GlcNAc2-P, generating GlcNAc-1-P and neutral Gn1-type free oligosaccharides.

ENGASE Protein Überblick

Protein Überblick

This gene encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides.

Genbezeichner und Symbole assoziert mit ENGASE

  • endo-beta-N-acetylglucosaminidase (Engase)
  • endo-beta-N-acetylglucosaminidase (ENGASE)
  • endo-beta-N-acetylglucosaminidase (engase)
  • C130099A03 Protein
  • D230014K01Rik Protein
  • RGD1310868 Protein

Bezeichner auf Proteinebene für ENGASE

cytosolic endo-beta-N-acetylglucosaminidase , Di-N-acetylchitobiosyl beta-N-acetylglucosaminidase , Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase , Cytosolic endo-beta-N-acetylglucosaminidase , ENGase

GENE ID SPEZIES
303702 Rattus norvegicus
64772 Homo sapiens
217364 Mus musculus
430102 Gallus gallus
561239 Danio rerio
Ausgewählte Anbieter für ENGASE Proteine (ENGASE)
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