ERO1-Like beta (S. Cerevisiae) Proteine (ERO1LB)

Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Zusätzlich bieten wir Ihnen ERO1-Like beta (S. Cerevisiae) Antikörper (63) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte ERO1LB ERO1LB 364755  
ERO1LB 56605 Q86YB8
ERO1LB 67475 Q8R2E9
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
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ERO1LB Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu ERO1-Like beta (S. Cerevisiae) (ERO1LB) Interaktionspartnern

Human ERO1-Like beta (S. Cerevisiae) (ERO1LB) Interaktionspartner

  1. This peptide, Ac-VDTTD-AFC, was efficiently cleaved by purified caspase-2 (zeige CASP2 Proteine) and auto-activating caspase-2 (zeige CASP2 Proteine) in mammalian cells, and exhibited better selectivity for caspase-2 (zeige CASP2 Proteine) relative to caspase-3 (zeige CASP3 Proteine) than reagents that are currently available.

  2. GJB2 (zeige GJB2 Proteine) and ERO1LB are implicated in pancreatic cancer progression and can be used to predict patient survival

  3. glutathione limits Ero1-dependent oxidation in the endoplasmic reticulum

  4. Ero1alpha and Ero1beta are retained in the endoplasmic reticulum by interactions with PDI (zeige PADI1 Proteine) and ERp44 (zeige ERP44 Proteine)

  5. the Ero FAD binding domain is critical for conformational stability, allowing Ero proteins to withstand stress conditions that cause client proteins to misfold

  6. The lack of correlation between changes in SAT adiponectin gene and protein expression and its circulating levels suggests that adipose tissue synthesis and release of adiponectin are highly regulated pathways.

Mouse (Murine) ERO1-Like beta (S. Cerevisiae) (ERO1LB) Interaktionspartner

  1. combined loss-of-function mutations in genes encoding the ER thiol oxidases ERO1alpha, ERO1beta, and PRDX4 (zeige PRDX4 Proteine) compromised the extracellular matrix and interfered with the intracellular maturation of procollagen

  2. Several lines of evidence suggest that ERO1lbeta is involved in maintaining insulin (zeige INS Proteine) content of pancreatic beta cells and in regulating beta cell survival during ER oxidative stress.

  3. An unexpectedly selective function for ERO1-beta in oxidative protein folding in insulin (zeige INS Proteine)-producing cells that is required for glucose homeostasis in vivo.

ERO1-Like beta (S. Cerevisiae) (ERO1LB) Protein Überblick

Protein Überblick

Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the being a source of oxidative stress. Required for the folding of cell, thereby being a source of oxidative stress.

Genbezeichner und Symbole assoziert mit ERO1LB

  • endoplasmic reticulum oxidoreductase 1 beta (Ero1b)
  • endoplasmic reticulum oxidoreductase 1 beta (ERO1B)
  • ERO1-like beta (S. cerevisiae) (Ero1lb)
  • 1300013B24Rik Protein
  • 1700065B09Rik Protein
  • AI447560 Protein
  • ero1-beta Protein
  • RGD1563548 Protein

Bezeichner auf Proteinebene für ERO1LB

ERO1-like protein beta , ERO1-like beta (S. cerevisiae) , endoplasmic reticulum oxidoreductin 1-Lbeta , ERO1-like protein beta-like , ERO1-L-beta , endoplasmic oxidoreductin-1-like protein B , oxidoreductin-1-L-beta , endoplasmic oxidoreductase 1 beta

GENE ID SPEZIES
364755 Rattus norvegicus
421509 Gallus gallus
469720 Pan troglodytes
488956 Canis lupus familiaris
514361 Bos taurus
100410296 Callithrix jacchus
100440749 Pongo abelii
100593455 Nomascus leucogenys
56605 Homo sapiens
67475 Mus musculus
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