ELMO/CED-12 Domain Containing 1 Proteine (ELMOD1)

Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family (By similarity).

alle Proteine anzeigen Gen GeneID UniProt
Ratte ELMOD1 ELMOD1 315670  
Human ELMOD1 ELMOD1 55531 Q8N336
Maus ELMOD1 ELMOD1 270162 Q3V1U8
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top ELMO/CED-12 Domain Containing 1 Proteine auf antikoerper-online.de

Showing 6 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
Details
Hefe Orang-Utan His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,876.50
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,876.50
Details

Weitere Proteine zu ELMO/CED-12 Domain Containing 1 (ELMOD1) Interaktionspartnern

Human ELMO/CED-12 Domain Containing 1 (ELMOD1) Interaktionspartner

  1. Data suggest that GPR124 promotes cell adhesion via interaction with Elmo1 (zeige ELMO1 Proteine)-Dock180 (zeige DOCK1 Proteine) and intersectin 1 (zeige ITSN1 Proteine)/2; this constitutes a previously unrecognized heteromeric complex that is putatively involved in GPR124-dependent adhesive/angiogenic responses in vascular endothelial cells. (GPR124 = G-protein coupled receptor 124; Elmo1 (zeige ELMO1 Proteine) = ELMO domain-containing protein 1; Dock180 (zeige DOCK1 Proteine) = dedicator of cytokinesis protein 1 (zeige DOCK1 Proteine) 180 kDa)

  2. The non-opioid sigma-1 receptor (S1R) was identified as a novel effector of GAP activity of ELMOD1-3 proteins as its direct binding to either ELMOD1 or ELMOD2 (zeige ELMOD2 Proteine) resulted in loss of GAP activity.

Mouse (Murine) ELMO/CED-12 Domain Containing 1 (ELMOD1) Interaktionspartner

  1. Elmod1 has relatively high and selective expression in the brain but as of 2014 has not been well-studied with respect to CNS function or disease associations. It is part of the core brain ignorome. Elmod1 has a high cis (zeige CISH Proteine)-eQTL (zeige EQTN Proteine) in hippocampus, hypothalamus, striatum. Hearing sensitivity trait in GeneNetwork.org also maps to the region containing Elmod1.

  2. This finding connecting ELMOD1 deficiencies with stereocilia dysmorphologies establishes a link between the Ras superfamily of small regulatory GTPases and the actin cytoskeleton dynamics of hair cell stereocilia.

ELMO/CED-12 Domain Containing 1 (ELMOD1) Protein Überblick

Protein Überblick

Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family (By similarity).

Genbezeichner und Symbole assoziert mit ELMOD1

  • ELMO domain containing 1 (Elmod1)
  • ELMO domain containing 1 (ELMOD1)
  • ELMO/CED-12 domain containing 1 (Elmod1)
  • 4831417L10 Protein
  • AI428506 Protein
  • AI834991 Protein
  • RGD1564186 Protein

Bezeichner auf Proteinebene für ELMOD1

ELMO domain containing 1 , ELMO domain-containing protein 1

GENE ID SPEZIES
315670 Rattus norvegicus
55531 Homo sapiens
270162 Mus musculus
768233 Bos taurus
100174164 Pongo abelii
Haben Sie etwas anderes gesucht?