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The protein encoded by DUSP8 is a member of the dual specificity protein phosphatase subfamily. Zusätzlich bieten wir Ihnen Dual Specificity Phosphatase 8 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 67 products:
Human Polyclonal DUSP8 Primary Antibody für ELISA, WB - ABIN257844
Martell, Seasholtz, Kwak, Clemens, Dixon: hVH-5: a protein tyrosine phosphatase abundant in brain that inactivates mitogen-activated protein kinase. in Journal of neurochemistry 1995
Human Polyclonal DUSP8 Primary Antibody für WB - ABIN4891910
Smeeton, Dhir, Hu, Feeney, Chen, Rosenblum: Integrin-linked Kinase Controls Renal Branching Morphogenesis via Dual Specificity Phosphatase 8. in Journal of the American Society of Nephrology : JASN 2016
The phosphorylation of the M3/6 phosphatase by JNK (zeige MAPK8 Antikörper) in response to stress stimuli results in attenuation of phosphatase activity and acceleration of JNK (zeige MAPK8 Antikörper) activation.
DUSP8 is genetically linked to alcohol dependence and was found on chromosome 11p15.5
Because this variant of hVH-5 lacked intronic sequences in its genomic structure, we suggest it might be a processed pseudogene of hVH-5.
DUSP8 controls stress-induced ERK1/2 signaling in cardiac myocytes.
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.
dual specificity phosphatase 8
, dual specificity protein phosphatase 8-like
, dual specificity protein phosphatase 8
, H1 phosphatase, vaccinia virus homolog
, dual specificity protein phosphatase hVH-5
, serine/threonine specific protein phosphatase
, neuronal tyrosine threonine phosphatase 1
, neuronal tyrosine/threonine phosphatase 1