anti-Dopachrome Tautomerase (DCT) Antikörper

Involved in regulating eumelanin and phaeomelanin levels.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Ratte DCT DCT 290484  
Anti-Maus DCT DCT 13190 P29812
Anti-Human DCT DCT 1638 P40126
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Top anti-DCT Antikörper auf antikoerper-online.de

Showing 10 out of 114 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-Dct Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  Mouse Heart Host:  Mouse  Target Name:  DCT  Sample Tissue:  Mouse Skeletal Muscle  Antibody Dilution:  1ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Dct Antibody Titration: 1.0 ug/ml Positive Control: Mouse Kidney 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of TRP2 staining in A375 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of TRP2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of DCT Antibody  in NCI-H460 cell line lysates (35ug/lane). This demonstrates the DCT antibody detected the DCT protein (arrow) 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of TRP2 expression in Hela (A), A549 (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of TRP2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated wit Western blot analysis of TRP2 expression in Hela (A), A549 (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from K562 cells, using DCT Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using DCT Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of DCT Antibody (N-term) (ABIN652717) in K562, A375, Ramos cell line lysates (35 µg/lane). DCT (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with DCT Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of DCT Antibody (N-term) (ABIN653914) in A375 cell line lysates (35 µg/lane). DCT (arrow) was detected using the purified polyclonal antibody. DCT Antibody (N-term) (ABIN653914) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ELISA, IF, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details

Am meisten referenzierte anti-DCT Antikörper

  1. Human Polyclonal DCT Primary Antibody für ICC, IF - ABIN4362889 : Pontén, Jirström, Uhlen: The Human Protein Atlas--a tool for pathology. in The Journal of pathology 2008 (PubMed)

  2. Human Polyclonal DCT Primary Antibody für IHC, IHC (p) - ABIN4362890 : Abad, Wieërs, Colau, Wildmann, Delair, Dhote, Brézin, Kawakami, Coulie, van der Bruggen: Absence of recognition of common melanocytic antigens by T cells isolated from the cerebrospinal fluid of a Vogt-Koyanagi-Harada patient. in Molecular vision 2014 (PubMed)

Weitere Antikörper gegen DCT Interaktionspartner

Mouse (Murine) Dopachrome Tautomerase (DCT) Interaktionspartner

  1. soyasaponin Ag inhibited TRP2 expression in a dosedependent manner. Therefore, the depigmenting effect of soyasaponin Ag may be due to the inhibition of tyrosinase (zeige TYR Antikörper) expression or the enhancement of tyrosinase (zeige TYR Antikörper) degradation.

  2. MIF-2 (zeige HSPA5 Antikörper)/D-DT is an early response cytokine in the I/R injury repair of the proximal tubule, enhancing regeneration through SLPI (zeige SLPI Antikörper)- and ATF4 (zeige ATF4 Antikörper)-dependent mechanisms.

  3. the slaty mutant melanocytes seem to be more sensitive to ultraviolet rays and oxidative stress than black melanocytes.

  4. A novel murine model of vitiligo (zeige MITF Antikörper) is established by sequential prime/boost immunizations into the hind footpad and tail dermis with tyrosinase-related protein 2 (TRP2)-180 (SVYDFFVWL) peptide.

  5. study indicates that tumor antigen (TRP2) expressed in MCMV induces a strong and long-lasting anti-melanoma effect through an antibody-dependent mechanism

  6. Vaccine formulations with synthetic long peptides for treating B16F10 skin melanoma fails to elicit strong CD8 (zeige CD8A Antikörper) T cell responses to self-differentiation antigens TRP-2 and gp100 (zeige PMEL Antikörper).

  7. level of gene targeting was not improved by the DSB induction, indicating a limited capacity of I-SceI to mediate homologous recombination at the Dct locus

  8. Recombinant dopachrome tautomerase was expressed and purified, without its carboxy-terminal transmembrane region. Analysis of dopachrome tautomerase tryptic peptides by MALDI-TOF/TOF (zeige FEZF2 Antikörper) determined N-glycosylation as a primary post-translational modification.

  9. Dopachrome tautomerase inactivation elevates the level of ROS (zeige ROS1 Antikörper), increases the numbers of sunburn cells and apoptotic cells, and decreases the amount of eumelanin in the epidermis upon exposure to chronic UVA radiation

  10. the TRP-2 polypeptide folds in the endoplasmic reticulum (ER) in the presence of calnexin (zeige CANX Antikörper), until it reaches a dithiothreitol-resistant conformation enabling its ER exit to the Golgi

Human Dopachrome Tautomerase (DCT) Interaktionspartner

  1. High DCT expression is associated with progressive multiple sclerosis.

  2. High DCT expression is associated with HPV16 Infection.

  3. Data indicate that the caveolin-1 (CAV1 (zeige CAV1 Antikörper)) control on dopachrome tautomerase (DCT) gene expression, DCT post-translational processing, and subcellular distribution is cell phenotype-dependent.

  4. The effect of DCT on UVR DNA damage responses and survival pathways in melanocytes was examined by knockdown experiments using melanoma cells, neonatal melanoblasts in monoculture and in co-culture with keratinocytes.

  5. Report dopachrome tautomerase expression in mealanocytic tumors.

  6. The results suggested that the miRNAs may be involved in MITF (zeige MITF Antikörper) regulation of TYR (zeige TYR Antikörper), TYRP1 (zeige TYRP1 Antikörper) and TYRP2, which provides a new clue for understanding the role of miRNAs in melanocyte dysfunctional disease.

  7. Data suggest that macrophage migration inhibitory factor (MIF (zeige MIF Antikörper)) and d-dopachrome tautomerase (zeige DDT Antikörper) (d-DT) act cooperatively to inhibit steady-state phosphorylation and activation of AMPK (zeige PRKAA1 Antikörper) in LKB1 (zeige STK11 Antikörper) wild type and LKB1 (zeige STK11 Antikörper) mutant non-small cell lung carcinomas cells.

  8. human TRP2 counteracts apoptotic cell death induction, possibly by means of its L-dopachrome tautomerase activity, and negatively affects the p53 (zeige TP53 Antikörper) pathway

  9. Trp2 SNP2 allele is a risk factor for the development and severity of degenerative disc disease in a Chinese Han population.

  10. Data suggest that OTX2 (zeige OTX2 Antikörper) may regulate retinal pigment epithelium (RPE (zeige RPE Antikörper))-specific target genes, such as DOPAchrome tautomerase (DCT), thereby maintaining the homeostasis of RPE (zeige RPE Antikörper).

DCT Antigen-Profil

Protein Überblick

Involved in regulating eumelanin and phaeomelanin levels.

Genbezeichner und Symbole assoziert mit DCT

  • dopachrome tautomerase (DCT) Antikörper
  • dopachrome tautomerase (Dct) Antikörper
  • dopachrome tautomerase (dct) Antikörper
  • dopachrome tautomerase L homeolog (dct.L) Antikörper
  • DT Antikörper
  • RGD1564975 Antikörper
  • slaty Antikörper
  • slt Antikörper
  • TRP-2 Antikörper
  • TRP2 Antikörper
  • Tyrp-2 Antikörper
  • Tyrp2 Antikörper
  • zgc:109860 Antikörper

Bezeichner auf Proteinebene für DCT

DT , L-dopachrome Delta-isomerase , L-dopachrome tautomerase , TRP-2 , TRP2 , dopachrome delta isomerase , dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) , tyrosinase related protein 2 , tyrosinase-related protein 2 , L-dopachrome tautomerase-like , SLATY locus protein , tyrosinase-related protein-2 , dopachrome delta-isomerase , tyrosine-related protein 2

GENE ID SPEZIES
280761 Bos taurus
574066 Sus scrofa
100170232 Ovis aries
290484 Rattus norvegicus
485520 Canis lupus familiaris
549915 Xenopus (Silurana) tropicalis
694577 Macaca mulatta
100058776 Equus caballus
100230498 Taeniopygia guttata
100381161 Xenopus laevis
100389709 Callithrix jacchus
100438537 Pongo abelii
100595345 Nomascus leucogenys
13190 Mus musculus
1638 Homo sapiens
395775 Gallus gallus
100353923 Oryctolagus cuniculus
100718804 Cavia porcellus
58074 Danio rerio
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