DnaJ (Hsp40) Homolog, Subfamily B, Member 8 Proteine (DNAJB8)

The protein encoded by DNAJB8 belongs to the DNAJ/HSP40 family of proteins that regulate chaperone activity. Zusätzlich bieten wir Ihnen DNAJB8 Antikörper (30) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
DNAJB8 165721 Q8NHS0
DNAJB8 56691 Q9QYI7
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Top DNAJB8 Proteine auf antikoerper-online.de

Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,465.26
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$400.00
Details

DNAJB8 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu DnaJ (Hsp40) Homolog, Subfamily B, Member 8 (DNAJB8) Interaktionspartnern

Human DnaJ (Hsp40) Homolog, Subfamily B, Member 8 (DNAJB8) Interaktionspartner

  1. DNAJB8 is a central and versatile player in the protein aggregation and degradation system.DNAJB8 protein keeps Parkin (zeige PARK2 Proteine) C289G mutant protein in a soluble, degradation-competent form.

  2. Results show that DNAJB8 expression is induced by heat shock stress which increases side population cells and cancer stem-like cells.

  3. Taken together, the results indicate that DNAJB8 is expressed and has role in CRC CSC/CIC and that DNAJB8 is a novel target of CRC CSC/CIC-targeting immunotherapy.

  4. The mechanism of DNAJB6 (zeige DNAJB6 Proteine) and DNAJB8 is suppression of polyQ protein aggregation by directly binding the polyQ tract.

  5. Cancer stem-like cell (CSC) maintenance and that it offers a candidate for CSC-targeting immunotherapy in renal cell carcinoma

  6. DNAJB6b and DNAJB8 are superior suppressors of aggregation and toxicity of disease-associated polyglutamine proteins.

Mouse (Murine) DnaJ (Hsp40) Homolog, Subfamily B, Member 8 (DNAJB8) Interaktionspartner

  1. Dnajb8 has a role in tumor initiation, side population ratio and sphere formation but it is dispensable for stress responses

  2. findings suggest that DNAJB8 plays a role in Cancer stem-like cell (CSC) maintenance and that it offers a candidate for CSC-targeting immunotherapy in renal cell carcinoma (zeige MOK Proteine)

DNAJB8 Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the DNAJ/HSP40 family of proteins that regulate chaperone activity. This family member suppresses aggregation and toxicity of polyglutamine proteins, and the C-terminal tail is essential for this activity. It has been implicated as a cancer-testis antigen and as a cancer stem-like cell antigen involved in renal cell carcinoma.

Genbezeichner und Symbole assoziert mit DNAJB8

  • DnaJ heat shock protein family (Hsp40) member B8 (DNAJB8)
  • DnaJ heat shock protein family (Hsp40) member B8 (Dnajb8)
  • 1700016F14Rik Protein
  • 1700031F10Rik Protein
  • AI326313 Protein
  • DJ6 Protein
  • mDj6 Protein

Bezeichner auf Proteinebene für DNAJB8

dnaJ homolog subfamily B member 8 , DnaJ homolog 6

GENE ID SPEZIES
165721 Homo sapiens
56691 Mus musculus
Ausgewählte Anbieter für DNAJB8 Proteine (DNAJB8)
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