anti-Disabled Homolog 1 (Drosophila) (DAB1) Antikörper

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. Zusätzlich bieten wir Ihnen DAB1 Kits (21) und DAB1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DAB1 1600 O75553
DAB1 266729 Q8CJH2
DAB1 13131 P97318
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Top anti-DAB1 Antikörper auf antikoerper-online.de

Showing 10 out of 140 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-DAB1 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>THP-1 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Huhn Kaninchen Unkonjugiert IC, IF, WB Immunofluorescent analysis of DAB1 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of DAB1 expression in MCF7 (A), HEK293T (B) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from HepG2/293 cells, using Dab1 (Ab-232) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of MCF7 cells, using Dab1 (Ab-232) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IF, ELISA, WB Western blot analysis of extracts from HeLa cells, using Dab1 (Ab-220) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using Dab1 (Ab-220) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from LOVO cells, using Dab1 (Phospho-Tyr232) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of DAB1 Antibody (Center) (ABIN652935) in mouse brain tissue lysates (35 µg/lane). DAB1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with DAB1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p) 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$368.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: DAB1 Antibody [NBP2-16095] - Sample: HepG2 cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: DAB1 protein stained by DAB1 antibody [N1N3] diluted at 1:500. Blue: Hoechst 33342 staining. Immunohistochemistry-Paraffin: DAB1 Antibody [NBP2-16095] - Immunohistochemical analysis of paraffin-embedded hela xenograft, using antibody at 1:500 dilution. 0.1 mL Anmelden zum Anzeigen 18 bis 20 Tage
$514.63
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-Phospho-Dab1 (Tyr232) Polyclonal Antibody, Unconjugated (ABIN684343) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat seminal vesicle labeled with Anti-Phospho-Dab1 (Tyr232) Polyclonal Antibody, Unconjugated (ABIN684343) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$328.90
Details
Human Kaninchen Unkonjugiert IF, IHC (p), ELISA, WB Human Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details

DAB1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-DAB1 Antikörper

  1. Human Polyclonal DAB1 Primary Antibody für IHC - ABIN965969 : Chen, Ochalski, Tran, Sahir, Schubert, Pramatarova, Howell: Interaction between Dab1 and CrkII is promoted by Reelin signaling. in Journal of cell science 2004 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen DAB1 Interaktionspartner

Zebrafish Disabled Homolog 1 (Drosophila) (DAB1) Interaktionspartner

  1. Alternatively spliced dab1 isoforms were identified.

Human Disabled Homolog 1 (Drosophila) (DAB1) Interaktionspartner

  1. these results establish an unstable repeat insertion in DAB1 as a cause of cerebellar degeneration.

  2. Study shows that early neural cells transiently express Reelin (zeige RELN Antikörper) at the time they leave the presumptive olfactory/vomeronasal epithelium and that Dab 1 is present in the migratory cell mass and in the presumptive ensheathing cells in the absence of reelin (zeige RELN Antikörper).

  3. this study is the first to provide genetic evidence for DAB1 as a candidate AD liability/protection gene, although the strength of the contribution of DAB1 may differ among populations

  4. results of this study demonstrated the presence of reelin (zeige RELN Antikörper), its receptors VLDLR (zeige VLDLR Antikörper) and ApoER2 (zeige LRP8 Antikörper) as well as Dab1 in the ENS and might indicate a novel role of the reelin (zeige RELN Antikörper) system in regulating neuronal plasticity and pre-synaptic functions in the ENS.

  5. The finding of this study suggested that variations in DAB1 involved in the Reelin signaling pathway might contribute to genetic susceptibility to autism with Chinese Han decent.

  6. Variation in genes encoding proteins at the gateway of Reelin (zeige RELN Antikörper) signaling: ligands RELN (zeige RELN Antikörper) and APOE (zeige APOE Antikörper), their common receptors APOER2 (zeige LRP8 Antikörper) and VLDLR (zeige VLDLR Antikörper), and adaptor DAB1, was examined.

  7. show that Reelin (zeige RELN Antikörper)-stimulated Notch-1 (zeige NOTCH1 Antikörper) activation is dependent on Reelin (zeige RELN Antikörper) signaling

  8. alternative splicing of Dab1 is conserved in avian and mammalian species, with Dab1-L driving SFK phosphorylation in both species

  9. we report for the first time, that DAB1 is significantly up-regulated in human frontal cortex brain samples of Alzheimer disease patients

  10. Dab1, an essential component of the reelin (zeige RELN Antikörper) pathway, is required for glia-independent somal translocation in the neocortex.

Mouse (Murine) Disabled Homolog 1 (Drosophila) (DAB1) Interaktionspartner

  1. RBX2 (zeige RNF7 Antikörper), a core component of the E3 ubiquitin ligase (zeige MUL1 Antikörper) CRL5, is essential for retinal layering and function. RBX2 (zeige RNF7 Antikörper) regulates the final cell position of rod bipolar cells, cone photoreceptors and Muller glia. Our data indicate that sustained RELN (zeige RELN Antikörper)/DAB1 signaling, triggered by depletion of RBX2 (zeige RNF7 Antikörper) or SOCS7 (zeige SOCS7 Antikörper) - a CRL5 substrate adaptor known to recruit DAB1 - causes rod bipolar cell misposition.

  2. Mice with low or no Dab1 expression exhibited reduced calling rates, altered call-type usage, and differential vocal development trajectories.

  3. Results showed that the Dab1 nuclear localization signal mutant can translocate into the nucleus via an unconventional temperature-dependent/ATP-dependent and cytoplasmic soluble factor-independent/RanGTP gradient-independent manner, suggesting that Dab1 has 2 (zeige HAS2 Antikörper) different nuclear translocation pathways; and that the regulation of subcellular localization of Dab1 is important for the proper migration of excitatory neurons.

  4. This study showed that spontaneous Dab1 mutations causing cerebellar pathology are impaired in motor functions during the neonatal period.

  5. an aberrant fragment of Dab1 protein (p64 (zeige IL2RG Antikörper)/60) is present in the brain of yotari mouse

  6. When pregnant mice are exposed to EMF, Dab1 expression increases in the EMF-treated fetal cerebral cortex extracts as compared to controls and SHAM group.

  7. It findings link reelin (zeige RELN Antikörper) with Dab1 and suggest that Dab1 functions downstream of reelin (zeige RELN Antikörper) action on the homeostasis of the crypt-villus unit.

  8. The results of this study indicate a causal relation between the downregulation of Dab1 protein levels during development and the structural and behavioral deficits associated with psychiatric diseases in the adult.

  9. The expression of Dab-1 was analyzed in the developing mouse autopod. Transcripts of Dab-1 were abundant in the autopodial tendon primordia, but transcripts were also present in the undifferentiated mesoderm located around the digits.

  10. results suggest a major role of VEGF (zeige VEGFA Antikörper) in the regulation of reelin (zeige RELN Antikörper) signaling, and Dab1 as a key molecule in the cross talk between reelin (zeige RELN Antikörper) and VEGF (zeige VEGFA Antikörper) signaling pathways.

Pig (Porcine) Disabled Homolog 1 (Drosophila) (DAB1) Interaktionspartner

  1. Alternative spliced forms of disabled homolog 1 (DAB1) have been isolated from brain and liver.

DAB1 Antigen-Profil

Protein Überblick

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Genbezeichner und Symbole assoziert mit DAB1

  • DAB1, reelin adaptor protein (DAB1) Antikörper
  • disabled homolog 1 (LOC100232823) Antikörper
  • Dab, reelin signal transducer, homolog 1a (Drosophila) (dab1a) Antikörper
  • DAB1, reelin adaptor protein (Dab1) Antikörper
  • disabled 1 (Dab1) Antikörper
  • AI956902 Antikörper
  • C630028C02Rik Antikörper
  • DAB1 Antikörper
  • disabled-1 Antikörper
  • LOC100232823 Antikörper
  • scm Antikörper
  • scr Antikörper
  • scrambler Antikörper
  • si:dkey-242m13.1 Antikörper
  • yot Antikörper

Bezeichner auf Proteinebene für DAB1

disabled homolog 1 , disabled1 , disabled homolog 1 (Drosophila) , DAB1 variant protein-like , disabled homolog 1-like , yotari

GENE ID SPEZIES
100049825 Equus caballus
100232823 Taeniopygia guttata
692351 Danio rerio
740508 Pan troglodytes
100337993 Oryctolagus cuniculus
100453388 Pongo abelii
100583389 Nomascus leucogenys
1600 Homo sapiens
266729 Rattus norvegicus
538818 Bos taurus
13131 Mus musculus
374083 Gallus gallus
610344 Canis lupus familiaris
100037307 Sus scrofa
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