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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Zusätzlich bieten wir Ihnen DAP3 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
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Frog Monoclonal DAP3 Primary Antibody für IF, IP - ABIN968095
Fulda, Debatin: IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway. in Oncogene 2002
Show all 4 Pubmed References
Human Polyclonal DAP3 Primary Antibody für ELISA - ABIN563476
Kim, Siesser, Rossman, Goldfarb, Mackinnon, Yan, Yi, MacCoss, Moon, Der, Major: Substrate trapping proteomics reveals targets of the ?TrCP2/FBXW11 ubiquitin ligase. in Molecular and cellular biology 2014
Human Polyclonal DAP3 Primary Antibody für ICC, IF - ABIN249521
Kissil, Deiss, Bayewitch, Raveh, Khaspekov, Kimchi: Isolation of DAP3, a novel mediator of interferon-gamma-induced cell death. in The Journal of biological chemistry 1996
Human Polyclonal DAP3 Primary Antibody für WB - ABIN537322
Berger, Kretzler: Interaction of DAP3 and FADD only after cellular disruption. in Nature immunology 2001
DAP3 plays important roles in mitochondrial function and dynamics
DAP3 silencing contributes to breast carcinogenesis.
Knockdown of DAP3 expression promoted cell migration.
Study demonstrates an inverse association between DAP3 mRNA levels and tumour stage and clinical outcome in breast cancer.
identified a novel DAP3-binding protein termed death ligand signal enhancer (DELE (zeige KIAA0141 Antikörper)); results demonstrated the biological significance of DELE (zeige KIAA0141 Antikörper) for apoptosis signal mediated by death receptors
show that interferon-beta (zeige IFNB1 Antikörper) promoter stimulator 1 (IPS-1 (zeige MAVS Antikörper)) binds DAP3 and induces anoikis by caspase (zeige CASP3 Antikörper) activation.
Functional interaction between the pro-apoptotic DAP3 and the glucocorticoid receptor (zeige NR3C1 Antikörper)
DAP3 has a role in the molecular pathway that culminates in fragmented mitochondria
DAP3 gene might be associated with the mechanisms responsible for adult bronchial asthma and contribute to airway inflammation and remodeling
DAP3 has a role in anoikis signaling and in apoptosis induction caused by cell detachment
Both constitutive and induced genetic deletion of the melanocortin 4 receptor (zeige MC4R Antikörper) gene(MC4R (zeige MC4R Antikörper)) normalizes compulsive grooming and striatal electrophysiologic impairments in SAPAP3 (zeige DLGAP3 Antikörper)-null mice
These results identify a role for SAPAP3 (zeige DLGAP3 Antikörper) in the regulation of postsynaptic metabotropic glutamate (zeige GRIN1 Antikörper) receptors and endocannabinoid-mediated synaptic plasticity.
DAP3 is critical for TCR-mediated induction of apoptosis at the downstream of Nur77 (zeige NR4A1 Antikörper).
Semi-quantitative analysis of RNA levels in FMRP (zeige FMR1 Antikörper) immunoprecipitates showed that in the mouse brain mRNAs encoding PSD (zeige PSD Antikörper) components, such as Shank1 (zeige SHANK1 Antikörper), SAPAP1 (zeige DLGAP1 Antikörper)-3, PSD-95 (zeige DLG4 Antikörper), and the glutamate (zeige GRIN1 Antikörper) receptor subunits NR1 (zeige GRIN1 Antikörper) and NR2B (zeige GRIN2B Antikörper), are associated with FMRP (zeige FMR1 Antikörper).
DAP3 is reduced in both replicative and premature senescence induced by oxidative stress, and the DAP3 reduction induced by oxidative stress is observed mostly in a mitochondrial fraction.
requirement for DAP3 in mitochondrial respiration was also revealed by oxygen consumption measurements using cultured cells treated with DAP3-specific small interfering RNA
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.
death-associated protein 3
, 28S ribosomal protein S29, mitochondrial
, ionizing radiation resistance conferring protein
, mitochondrial 28S ribosomal protein S29
, PSD-95/SAP90-binding protein 3
, SAP90/PSD 95 associated protein 3
, disks large-associated protein 3
, prion protein ligand 8