Dead End Homolog 1 (Zebrafish) Proteine (DND1)

DND1 encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Zusätzlich bieten wir Ihnen Dead End Homolog 1 (Zebrafish) Antikörper (40) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
DND1 213236 Q6VY05
DND1 373863 Q8IYX4
Ratte DND1 DND1 679841  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top Dead End Homolog 1 (Zebrafish) Proteine auf antikoerper-online.de

Showing 2 out of 2 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,960.83
Details

DND1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human

Weitere Proteine zu Dead End Homolog 1 (Zebrafish) (DND1) Interaktionspartnern

Mouse (Murine) Dead End Homolog 1 (Zebrafish) (DND1) Interaktionspartner

  1. DND1 binds a UU(A/U) trinucleotide motif predominantly in the 3' untranslated regions of mRNA, and destabilizes target mRNAs through direct recruitment of the CCR4 (zeige CCR4 Proteine)-NOT deadenylase complex.

  2. DND1 interacts with NANOS2 (zeige NANOS2 Proteine) to load unique RNAs into the CCR4 (zeige CCR4 Proteine)-NOTdeaden complex; this interaction is mediated by the zinc finger domain of NANOS2 (zeige NANOS2 Proteine), which is essential for its association with target RNAs; DND1 is an essential partner for NANOS2 (zeige NANOS2 Proteine) that leads to the degradation of specific RNAs in male germ cell development

  3. Dnd1 heterozygotes, lower oxygen availability was associated with metabolic differences

  4. APOBEC3G (zeige APOBEC3G Proteine) inhibits DND1 function to regulate microRNA activity.

  5. results show that Dnd1 is essential for normal allelic inheritance and that Dnd1Ter has a novel combination of functions that significantly increase risk for both testicular and intestinal cancer

  6. DND1 is the first protein known to have an RNA recognition motif directly implicated as a heritable cause of spontaneous tumorigenesis

  7. DND1-alpha isoform to be necessary for germ cell viability and its loss in Ter (zeige TECR Proteine) mice results in germ cell depletion, germ cell tumor development and partial embryonic lethality in the 129 strain.

  8. The role of dead-end in germ-cell tumor development.

  9. The interaction of DND1 and APOBEC3 could be one mechanism for maintaining viability of germ cells and for preventing germ cell tumor development

  10. when Dnd1(Ter/Ter) XX germ cells developed in a testicular environment they gave rise to the same neoplastic clusters as mutant XY germ cells in a testis.

Human Dead End Homolog 1 (Zebrafish) (DND1) Interaktionspartner

  1. Dnd1 facilitates apoptosis by increasing the expression of Bim via its competitive combining with miR-221 in Bim-3'UTR.

  2. RBM38 (zeige RBM38 Proteine) and DND1 are repressed in primary acute myeloid leukemia (zeige BCL11A Proteine), neutrophil differentiation is dependent on increased expression of both proteins, and they have a role in regulating p21(CIP1 (zeige CDKN1A Proteine)) expression during acute promyelocytic leukemia (zeige PML Proteine) differentiation

  3. APOBEC3G (zeige APOBEC3G Proteine) inhibits DND1 function to regulate microRNA activity.

  4. The increased sensitivity of transformed keratinocytes to miR (zeige MLXIP Proteine)-21's effects occurs in part through downregulation of the RNA-binding protein (zeige PTBP1 Proteine) DND1 during the transformation process.

  5. Results suggest that DND1 may impose another level of translational regulation to modulate expression of critical factors in ES cells.

  6. We conclude that germline DND1 mutations are unlikely to contribute significantly to human testicular germ cell tumor susceptibility

  7. Cloning of zebrafish dnd1 and identification of human DND1 by database analysis.

  8. Unravels a novel role of Dnd1 in protecting certain mRNAs from miRNA-mediated repression.

  9. MiR (zeige MLXIP Proteine)-24 up-regulation reduced the expression of RNA-binding protein (zeige PTBP1 Proteine) dead end 1 (zeige VPS11 Proteine) (DND1). Knockdown of miR (zeige MLXIP Proteine)-24 led to enhanced expression of DND1.

  10. The variant, p. Glu86Ala, found in only one case of testiciular germ cell tumor, is within a known functional domain of DND1 and is highly conserved through evolution; mutations in DND1 make, at most, a very small contribution to TGCT susceptibility

Dead End Homolog 1 (Zebrafish) (DND1) Protein Überblick

Protein Überblick

This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17.

Genbezeichner und Symbole assoziert mit DND1

  • DND microRNA-mediated repression inhibitor 1 (dnd1)
  • dead end protein homolog 1 pseudogene (LOC100349427)
  • DND microRNA-mediated repression inhibitor 1 (DND1)
  • DND microRNA-mediated repression inhibitor 1 (Dnd1)
  • BC034897 Protein
  • dead-end Protein
  • dnd Protein
  • DND1 Protein
  • RBMS4 Protein
  • Ter Protein
  • xde Protein
  • Xdead Protein

Bezeichner auf Proteinebene für DND1

dead end homolog 1 , dead end homolog 1 (zebrafish) , dead end protein homolog 1-like , dead end protein homolog 1 , RNA-binding motif, single-stranded-interacting protein 4 , teratoma

GENE ID SPEZIES
733500 Xenopus (Silurana) tropicalis
100349427 Oryctolagus cuniculus
425270 Gallus gallus
462121 Pan troglodytes
100061778 Equus caballus
100441044 Pongo abelii
100604987 Nomascus leucogenys
607141 Canis lupus familiaris
525516 Bos taurus
213236 Mus musculus
373863 Homo sapiens
679841 Rattus norvegicus
Ausgewählte Anbieter für Dead End Homolog 1 (Zebrafish) Proteine (DND1)
Haben Sie etwas anderes gesucht?