anti-Dead End Homolog 1 (Zebrafish) (DND1) Antikörper

DND1 encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Zusätzlich bieten wir Ihnen Dead End Homolog 1 (Zebrafish) Proteine (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DND1 213236 Q6VY05
DND1 373863 Q8IYX4
DND1 679841  
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Top anti-Dead End Homolog 1 (Zebrafish) Antikörper auf antikoerper-online.de

Showing 10 out of 37 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-DND1 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate DND1 is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit Anti-DND1 Antibody     Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue  Observed Staining: Cytoplasmic in pinealocytes  Primary Antibody Concentration: 1:100  Other Working Concentrations: 1/600  Secondary Antibody: Donkey anti-Rabbit-Cy3  Secondary Antibody Concentration: 1:200  Magnification: 20X  Exposure Time: 0.5 - 2.0 sec 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host:  Rabbit  Target Name:  Dnd1  Sample Type:  Rat Small Intestine lysates  Antibody Dilution:  1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of DND1 Antibody  in Hela cell line lysates (35ug/lane).This demonstrates the DND1 antibody detected the DND1 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$484.00
Details
Hund Kaninchen Unkonjugiert IHC, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-DND1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. O ... 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$727.83
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB DND1 Antibody (Center)  western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the DND1 antibody detected the DND1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
Details
Human Maus Unkonjugiert ELISA, WB DND1 monoclonal antibody (M07), clone 2G11 Western Blot analysis of DND1 expression in Hela S3 NE . DND1 monoclonal antibody (M07), clone 2G11. Western Blot analysis of DND1 expression in NIH/3T3 . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis in Hela cell line lysates (35ug/lane). 400 μL Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Maus Unkonjugiert IF, ELISA, WB Immunofluorescence of monoclonal antibody to DND1 on HeLa cell. [antibody concentration 10 ug/ml] Western Blot detection against Immunogen (36.34 KDa) . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details

Weitere Antikörper gegen Dead End Homolog 1 (Zebrafish) Interaktionspartner

Mouse (Murine) Dead End Homolog 1 (Zebrafish) (DND1) Interaktionspartner

  1. Cultured Dead-end1 (Dnd1) mutant germ cells (CDGCs) were morphologically similar to embryonic stem cells (ESCs) and could be maintained in the naive pluripotent condition.

  2. DND1 binds a UU(A/U) trinucleotide motif predominantly in the 3' untranslated regions of mRNA, and destabilizes target mRNAs through direct recruitment of the CCR4-NOT deadenylase complex.

  3. DND1 interacts with NANOS2 to load unique RNAs into the CCR4-NOTdeaden complex; this interaction is mediated by the zinc finger domain of NANOS2, which is essential for its association with target RNAs; DND1 is an essential partner for NANOS2 that leads to the degradation of specific RNAs in male germ cell development

  4. Dnd1 heterozygotes, lower oxygen availability was associated with metabolic differences

  5. APOBEC3G inhibits DND1 function to regulate microRNA activity.

  6. results show that Dnd1 is essential for normal allelic inheritance and that Dnd1Ter has a novel combination of functions that significantly increase risk for both testicular and intestinal cancer

  7. DND1 is the first protein known to have an RNA recognition motif directly implicated as a heritable cause of spontaneous tumorigenesis

  8. DND1-alpha isoform to be necessary for germ cell viability and its loss in Ter mice results in germ cell depletion, germ cell tumor development and partial embryonic lethality in the 129 strain.

  9. Trans-generational epistasis between Dnd1Ter and other modifier genes controls susceptibility to testicular germ cell tumors.

  10. The role of dead-end in germ-cell tumor development.

  11. The interaction of DND1 and APOBEC3 could be one mechanism for maintaining viability of germ cells and for preventing germ cell tumor development

  12. when Dnd1(Ter/Ter) XX germ cells developed in a testicular environment they gave rise to the same neoplastic clusters as mutant XY germ cells in a testis.

Human Dead End Homolog 1 (Zebrafish) (DND1) Interaktionspartner

  1. Mechanistically, Dnd1 could bind to 3'-UTR of LATS2, the key kinase of Hippo pathway, thus elevating LATS2 mRNA stability and its expression, subsequently leading to phosphorylation of YAP and its cytoplasmic retention.

  2. Dnd1 facilitates apoptosis by increasing the expression of Bim via its competitive combining with miR-221 in Bim-3'UTR.

  3. RBM38 and DND1 are repressed in primary acute myeloid leukemia, neutrophil differentiation is dependent on increased expression of both proteins, and they have a role in regulating p21(CIP1) expression during acute promyelocytic leukemia differentiation

  4. APOBEC3G inhibits DND1 function to regulate microRNA activity.

  5. The increased sensitivity of transformed keratinocytes to miR-21's effects occurs in part through downregulation of the RNA-binding protein DND1 during the transformation process.

  6. Results suggest that DND1 may impose another level of translational regulation to modulate expression of critical factors in ES cells.

  7. We conclude that germline DND1 mutations are unlikely to contribute significantly to human testicular germ cell tumor susceptibility

  8. Cloning of zebrafish dnd1 and identification of human DND1 by database analysis.

  9. Unravels a novel role of Dnd1 in protecting certain mRNAs from miRNA-mediated repression.

  10. MiR-24 up-regulation reduced the expression of RNA-binding protein dead end 1 (DND1). Knockdown of miR-24 led to enhanced expression of DND1.

  11. The variant, p. Glu86Ala, found in only one case of testiciular germ cell tumor, is within a known functional domain of DND1 and is highly conserved through evolution; mutations in DND1 make, at most, a very small contribution to TGCT susceptibility

Dead End Homolog 1 (Zebrafish) (DND1) Antigen-Profil

Protein Überblick

This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17.

Genbezeichner und Symbole assoziert mit DND1

  • DND microRNA-mediated repression inhibitor 1 (dnd1) Antikörper
  • dead end protein homolog 1 pseudogene (LOC100349427) Antikörper
  • DND microRNA-mediated repression inhibitor 1 (DND1) Antikörper
  • DND microRNA-mediated repression inhibitor 1 (Dnd1) Antikörper
  • BC034897 Antikörper
  • dead-end Antikörper
  • dnd Antikörper
  • DND1 Antikörper
  • RBMS4 Antikörper
  • Ter Antikörper
  • xde Antikörper
  • Xdead Antikörper

Bezeichner auf Proteinebene für DND1

dead end homolog 1 , dead end homolog 1 (zebrafish) , dead end protein homolog 1-like , dead end protein homolog 1 , RNA-binding motif, single-stranded-interacting protein 4 , teratoma

GENE ID SPEZIES
733500 Xenopus (Silurana) tropicalis
100349427 Oryctolagus cuniculus
425270 Gallus gallus
462121 Pan troglodytes
100061778 Equus caballus
100441044 Pongo abelii
100604987 Nomascus leucogenys
607141 Canis lupus familiaris
525516 Bos taurus
213236 Mus musculus
373863 Homo sapiens
679841 Rattus norvegicus
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