anti-DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) (DMC1) Antikörper

The protein encoded by DMC1 is essential for meiotic homologous recombination. Zusätzlich bieten wir Ihnen DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) Kits (5) und DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DMC1 13404 Q61880
DMC1 11144 Q14565
DMC1 362960  
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Top anti-DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) Antikörper auf antikoerper-online.de

Showing 10 out of 128 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit Target Name: DMC1 Sample Type: Fetal Heart Antibody Dilution: 1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human heart tissue, using DMC1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded Cal27 xenograft , using DMC1, antibody at 1:500 dilution. IHC-P Image DMC1 antibody [N1C1] detects DMC1 protein at nucleolus on mouse testis by immunohistochemical analysis. Sample: Paraffin-embedded mouse testis. DMC1 antibody [N1C1] , dilution: 1:500. 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert EIA, FACS, IHC (p), WB Flow cytometric analysis of CEM cells using DMC1 Antibody (N-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin-fixed and paraffin-embedded human testis tissue reacted with DMC1 antibody (N-term) followed followed by peroxidase-conjugated secondary antibody and DAB staining. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of DMC1 Antibody (N-term) (ABIN653277) in MDA-MB435 cell line lysates (35 µg/lane). DMC1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human testis tissue reacted with DMC1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$385.00
Details
Human Maus Unkonjugiert IP, WB Western blot detection of DMC (37 kDa) from mouse testes using ABIN151318 (1:1000). Western Blot: DMC1 Antibody (1D12/4) [ABIN151318] - Analysis of DMC1 on human testis using ABIN151318. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$418.10
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry: DMC1 Antibody [NBP1-82838] - Staining of human testis shows strong nuclear positivity in subsets of cells in ductus seminiferus. Western Blot: DMC1 Antibody [NBP1-82838] - Lane 1: Mouse liver tissue lysate Lane 2: Rat liver tissue lysate 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$494.38
Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
$537.17
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extract of various cells, using DMC1 antibody. 100 μL Anmelden zum Anzeigen 11 bis 13 Tage
$366.77
Details

Am meisten referenzierte anti-DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) Antikörper

  1. Human Monoclonal DMC1 Primary Antibody für IP, WB - ABIN151318 : Masson, Davies, Hajibagheri, Van Dyck, Benson, Stasiak, Stasiak, West: The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51. in The EMBO journal 2000 (PubMed)

  2. Monoclonal DMC1 Primary Antibody für WB - ABIN534072 : Massey, Kaushik, Sovak, Kiffin, Cuervo: Consequences of the selective blockage of chaperone-mediated autophagy. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

Weitere Antikörper gegen DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) Interaktionspartner

Mouse (Murine) DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) (DMC1) Interaktionspartner

  1. we observed the occurrence of synaptonemal complex bridges between bivalents, most likely representing chromosome translocation events that may involve DMC1, RAD51 or 53BP1.

  2. The DMC1 was highly variable from cell to cell, whereas foci of the crossover marker MLH1 showed little variability.

  3. RAD51AP1 foci colocalize with a subset of DMC1 foci in spermatocytes.

  4. p53 might be involved in homologous recombination and/or checkpoint function by directly binding to DMC1 protein to repress genomic instability in meiotic germ cells

  5. TBPIP/HOP2 directly binds to DNA and functions as an activator for DMC1 during the homologous pairing step in meiosis

  6. data reveal an interplay among Hop2, Mnd1 and Rad51 and Dmc1 in the formation of the first recombination intermediates during meiosis

  7. Mei1 can be positioned upstream of Dmc1 in the genetic pathway that operates during mammalian meiosis

  8. Dmc1(Mei11) exposes a sex difference in recombination in that a significant portion of female oocytes can compensate for DMC1 deficiency to undergo crossing-over and complete gametogenesis.

Human DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) (DMC1) Interaktionspartner

  1. Data indicate that ahomologous pairing by DMC1 protein or RAD51 recombinase in chromatin containing nucleosome-depleted double-stranded DNA (dsDNA) regions.

  2. BRCA2 protein stimulates DMC1-mediated DNA strand exchange between RPA-ssDNA complexes and duplex DNA, thus identifying BRCA2 as a mediator of DMC1 recombination function.

  3. Dmc1 can reject divergent DNA sequences while bypassing a few mismatches in the DNA sequence.

  4. In contrast to RAD51, stabilization of the presynaptic filament via ATP hydrolysis attenuation is insufficient for enhancement of the DMC1-catalyzed recombination reaction.

  5. truncated DMC1 octamers further stack with alternate polarity into a filament

  6. results suggested mutations in the coding sequence of DMC1 are not associated with premature ovarian failure in Chinese women

  7. conserved lysine in the Walker A motif of hDMC1 is critical for ATP binding.

  8. The results suggested that PSF may function as an activator for the meiosis-specific recombinase DMC1.

  9. RAD51-associated protein 1 (RAD51AP1) interacts with the meiotic recombinase DMC1 through a conserved motif.

  10. RAD51AP1 foci colocalize with a subset of DMC1 foci in spermatocytes.

  11. D-loops in a human DMC1-driven reaction are substantially more resistant to dissociation by branch-migration proteins such as RAD54 than those formed by RAD51.

  12. the Dmc1 filament formed on single-stranded DNA has a mass per unit length expected from approximately 6.5 subunits per turn

  13. p53 might be involved in homologous recombination and/or checkpoint function by directly binding to DMC1 protein to repress genomic instability in meiotic germ cells

  14. The monomeric structure of the Dmc1 protein closely resembled those of the human and archaeal Rad51 proteins. We found another hydrogen bonding interaction at the polymer interface.

  15. hDmc1-mediated DNA recombination initiates through the nucleation of hDmc1 onto ssDNA to form a helical nucleoprotein filament

  16. N-terminal domain of DMC1 is required for the formation of the octamer, which may support the proper DNA binding activity of the DMC1 protein.

  17. activation of hDmc1 is mediated through conformational changes induced by free Ca2+ ion binding to a protein site that is distinct from the Mg2+.ATP-binding center

  18. BRCA2 binds the meiosis-specific recombinase DMC1 and define the primary DMC1 interaction site to a 26 amino-acid region

  19. Hop2/Mnd1 greatly stimulates Dmc1 to promote synaptic complex formation on long duplex DNAs

  20. Data show that DMC1 mutations may be one explanation for premature ovarian failure.

DMC1 Dosage Suppressor of Mck1 Homolog, Meiosis-Specific Homologous Recombination (Yeast) (DMC1) Antigen-Profil

Protein Überblick

The protein encoded by this gene is essential for meiotic homologous recombination. Genetic recombination in meiosis plays an important role in generating diversity of genetic information. The product of this gene is structurally and evolutionary related to the products of the yeast RAD51 and E. coli RecA genes. Alternative splice variants of this gene have been described but their full-length nature has not been determined.

Genbezeichner und Symbole assoziert mit DMC1

  • DNA meiotic recombinase 1 (DMC1) Antikörper
  • DNA meiotic recombinase 1 (dmc1) Antikörper
  • DNA meiotic recombinase 1 (Dmc1) Antikörper
  • DCM1 Antikörper
  • dJ199H16.1 Antikörper
  • DMC1 Antikörper
  • DMC1H Antikörper
  • LIM15 Antikörper
  • Mei11 Antikörper
  • sgdp Antikörper
  • zgc:136628 Antikörper

Bezeichner auf Proteinebene für DMC1

DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) , RecA homolog Dmc1 , disrupted meiotic cDNA 1 , meiotic recombination protein DMC1/LIM15 homolog , meiotic recombination protein DMC1/LIM15 homolog-like , meiotic recombination protein dmc1/lim15-like protein , disrupted meiotic cDNA 1 homolog , DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination , disrupted meiotic cDNA1, yeast, homolog of

GENE ID SPEZIES
458831 Pan troglodytes
553953 Danio rerio
608268 Canis lupus familiaris
100055204 Equus caballus
100408835 Callithrix jacchus
100473602 Ailuropoda melanoleuca
100528115 Ictalurus punctatus
100013547 Monodelphis domestica
100579935 Nomascus leucogenys
13404 Mus musculus
427903 Gallus gallus
100522866 Sus scrofa
618398 Bos taurus
11144 Homo sapiens
362960 Rattus norvegicus
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