Cytohesin 2 (CYTH2) ELISA Kits

The protein encoded by CYTH2 is a member of the PSCD family. Zusätzlich bieten wir Ihnen Cytohesin 2 Antikörper (82) und Cytohesin 2 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
CYTH2 9266 Q99418
Anti-Ratte CYTH2 CYTH2 116692 P63035
Anti-Maus CYTH2 CYTH2 19158 P63034
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 2.34 pg/mL 9.375-600 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
Details

Weitere ELISA Kits für Cytohesin 2 Interaktionspartner

Human Cytohesin 2 (CYTH2) Interaktionspartner

  1. ARNO-ARF1 regulates formation of podosomes by inhibition of RhoA/myosin-II and promotion of actin core assembly.

  2. Authors' experiments argue against ARNO being a robust modifier of EGFR (zeige EGFR ELISA Kits) catalytic activity.

  3. Data establish a role for cytohesin-2/ARNO as a regulator of R-Ras and integrin recycling and suggest that ARF-regulated trafficking of R-Ras is required for R-Ras-dependent effects on spreading and adhesion formation.

  4. The authors show that Shigella flexneri IpgD phosphatase activity is required for recruitment of the ARF6 (zeige ARF6 ELISA Kits) guanine nucleotide exchange factor (zeige RASGRF1 ELISA Kits) (GEF) ARF nucleotide binding site opener (ARNO) to bacterial entry sites.

  5. inhibiting cytohesins or ARNO as cytoplasmic activators of EGFR (zeige EGFR ELISA Kits) and IGF-I (zeige IGF1 ELISA Kits) in colorectal cancer resulted in anti-proliferation, reduced invasion, decreased migration, and suppressed growth in vivo and in vitro.

  6. Cytohesin-2 constitutively suppresses platelet dense granule secretion and aggregation by keeping ARF6 (zeige ARF6 ELISA Kits) in a GTP (zeige AK3 ELISA Kits)-bound state

  7. Expression of CYTH2 mutant deficient of the EFh2 domain in cells also inhibits Arf6 (zeige ARF6 ELISA Kits) activation and neurite extension.

  8. Phosphorylation of Ser392 of ARNO stabilized the C-terminal alpha-helix via formation of salt bridges between phospho-Ser392 and Arg390, Lys395, and Lys396.

  9. There is an association between cytohesin-2 expression and overall survival and disease-free survival in patients with hepatocellular carcinoma.

  10. Arf6 (zeige ARF6 ELISA Kits)/ ARNO signaling mediates phospholipase-D (zeige PLD ELISA Kits), ERK1/2 (zeige MAPK1/3 ELISA Kits) and cofilin (zeige CFL1 ELISA Kits) activation in pancreatic beta-cells.

Mouse (Murine) Cytohesin 2 (CYTH2) Interaktionspartner

  1. results show that ARNO interaction with the RLIP76 (zeige RALBP1 ELISA Kits) N-terminus regulates cell spreading and motility via PI3K and Arf6 (zeige ARF6 ELISA Kits), independent of RLIP76 (zeige RALBP1 ELISA Kits) control of Rac (zeige AKT1 ELISA Kits)

  2. The RLIP76 (zeige RALBP1 ELISA Kits)/R-Ras/ARNO complex localizes to recycling endosomes.

  3. signaling through cytohesin-2 is required for myelination by Schwann cells, and cytohesin-2 is added to the list of molecules known to underlie PNS myelination

  4. results together suggest that cytohesin 2 activates ARF6 (zeige ARF6 ELISA Kits) in a PI3K dependent manner and then the active ARF6 (zeige ARF6 ELISA Kits) causes phosphorylation of ERK1/2 (zeige MAPK1/3 ELISA Kits) during preadipocyte migration.

  5. Cytohesin-2 constitutively suppresses platelet dense granule secretion and aggregation by keeping ARF6 (zeige ARF6 ELISA Kits) in a GTP (zeige AK3 ELISA Kits)-bound state

  6. Expression of CYTH2 mutant deficient of the EFh2 domain in cells also inhibits Arf6 (zeige ARF6 ELISA Kits) activation and neurite extension.

  7. The N termini of a-subunit isoforms are involved in signaling between vacuolar H+-ATPase (V-ATPase (zeige DNAH8 ELISA Kits)) and cytohesin-2

  8. role for endothelial ARNO in VEGF (zeige VEGFA ELISA Kits)-dependent initiation of angiogenesis by regulation of VEGFR-2 (zeige KDR ELISA Kits) internalization in endothelial cells, resulting in the activation of the Akt (zeige AKT1 ELISA Kits) pathway, vessel permeability, and ultimately endothelial proliferation

  9. cytohesin-2, through a previously unexplored complex formation with paxillin, regulates preadipocyte migration; paxillin plays a previously unknown role as a scaffold protein of Arf guanine-nucleotide exchange factor

  10. Specific motifs of the V-ATPase a2 (zeige ATP6V0A2 ELISA Kits)-subunit isoform interact with catalytic and regulatory domains of ARNO.

Cytohesin 2 (CYTH2) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit Cytohesin 2 (CYTH2) ELISA Kits

  • cytohesin-2 (PTRG_08834) Antikörper
  • cytohesin 2 L homeolog (cyth2.L) Antikörper
  • cytohesin 2 (cyth2) Antikörper
  • cytohesin 2 (CYTH2) Antikörper
  • cytohesin 1 S homeolog (cyth1.S) Antikörper
  • cytohesin 2 (Cyth2) Antikörper
  • Arno Antikörper
  • CLM2 Antikörper
  • CTS18 Antikörper
  • CTS18.1 Antikörper
  • CYTH2 Antikörper
  • MGC80440 Antikörper
  • MGC84366 Antikörper
  • Pscd2 Antikörper
  • PSCD2L Antikörper
  • Sec7 Antikörper
  • Sec7B Antikörper
  • SEC7L Antikörper
  • Sec7p-L Antikörper
  • Sec7p-like Antikörper

Bezeichner auf Proteinebene für Cytohesin 2 (CYTH2) ELISA Kits

cytohesin-2 , cytohesin 2 , pleckstrin homology, Sec7 and coiled/coil domains 2 , pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2) , cytohesin-2-like , ARF exchange factor , ARF nucleotide-binding site opener , PH, SEC7 and coiled-coil domain-containing protein 2 , pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2) , ARF nucleotide binding site opener , CLM2 , SEC7 homolog B , pleckstrin homology, Sec7 and coiled-coil domains 2 , mSec7-2

GENE ID SPEZIES
6347120 Pyrenophora tritici-repentis Pt-1C-BFP
444689 Xenopus laevis
448569 Xenopus (Silurana) tropicalis
718682 Macaca mulatta
746757 Pan troglodytes
779436 Xenopus laevis
100216436 Ovis aries
100387102 Callithrix jacchus
100440057 Pongo abelii
9266 Homo sapiens
116692 Rattus norvegicus
19158 Mus musculus
476423 Canis lupus familiaris
768035 Bos taurus
100240721 Sus scrofa
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