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Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. Zusätzlich bieten wir Ihnen CYBB Kits (11) und CYBB Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 114 products:
Human Polyclonal CYBB Primary Antibody für IF (cc), IF (p) - ABIN750688
Dalaklioglu, Tasatargil, Kale, Tanriover, Dilmac, Erin: Metastatic breast carcinoma induces vascular endothelial dysfunction in Balb-c mice: Role of the tumor necrosis factor-? and NADPH oxidase. in Vascular pharmacology 2013
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Mouse (Murine) Monoclonal CYBB Primary Antibody für IF, WB - ABIN968524
Jacobsen, Skalnik: YY1 binds five cis-elements and trans-activates the myeloid cell-restricted gp91(phox) promoter. in The Journal of biological chemistry 1999
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Human Polyclonal CYBB Primary Antibody für IHC (p), WB - ABIN3044252
Liao, Liu, Guo, Zhang, Zhang: Oxidative burst of circulating neutrophils following traumatic brain injury in human. in PLoS ONE 2013
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Human Polyclonal CYBB Primary Antibody für IHC, IHC (p) - ABIN4301440
Rajtik, Carnicka, Szobi, Giricz, O-Uchi, Hassova, Svec, Ferdinandy, Ravingerova, Adameova: Oxidative activation of CaMKIIδ in acute myocardial ischemia/reperfusion injury: A role of angiotensin AT1 receptor-NOX2 signaling axis. in European journal of pharmacology 2016
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Mouse (Murine) Monoclonal CYBB Primary Antibody für IF, WB - ABIN968523
Suzuki, Kumatori, Haagen, Fujii, Sadat, Jun, Tsuji, Roos, Nakamura: PU.1 as an essential activator for the expression of gp91(phox) gene in human peripheral neutrophils, monocytes, and B lymphocytes. in Proceedings of the National Academy of Sciences of the United States of America 1998
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Human Monoclonal CYBB Primary Antibody für ICC, IF - ABIN1042596
Burritt, Quinn, Jutila, Bond, Jesaitis: Topological mapping of neutrophil cytochrome b epitopes with phage-display libraries. in The Journal of biological chemistry 1995
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Human Polyclonal CYBB Primary Antibody für ELISA, IHC - ABIN4301436
Zhu, Lindsey, Konieczna, Eklund: Constitutive activation of SHP2 protein tyrosine phosphatase inhibits ICSBP-induced transcription of the gene encoding gp91PHOX during myeloid differentiation. in Journal of leukocyte biology 2008
Human Monoclonal CYBB Primary Antibody für WB - ABIN1042597
Baniulis, Burritt, Taylor, Dinauer, Heyworth, Parkos, Magnusson, Jesaitis: Monoclonal antibody CL5 recognizes the amino terminal domain of human phagocyte flavocytochrome b558 large subunit, gp91phox. in European journal of haematology 2005
The nox1 (zeige NOX1 Antikörper), nox2/cybb expression in zebrafish during early nervous system development from 12 to 48 hours post fertilization
Data indicate that NADPH oxidase (zeige NOX1 Antikörper) NOx2 inhibition attenuates endoplasmic reticulum (ER) stress and apoptosis.
Nox2 activity efficiently contributes to the mechanism of oxidative stress-induced (zeige SQSTM1 Antikörper) increase in premature aging conferred by doxorubicin. The importance of modulation of Nox2 in human EPCs could reveal a useful tool to restore endothelial progenitor cells physiological function and properties.
We examined the pattern of NOX expression in spinal cords of patients and mouse models of ALS (zeige IGFALS Antikörper) and analyzed the impact of genetic deletion of the NOX1 (zeige NOX1 Antikörper) and 2 isoforms as well as pharmacological NOX inhibition in the SOD1 (zeige SOD1 Antikörper)(G93A) ALS (zeige IGFALS Antikörper) mouse model.In contrast to previous publications, survival of SOD1 (zeige SOD1 Antikörper)(G93A) mice was not modified upon breeding with constitutive NOX1 (zeige NOX1 Antikörper) and NOX2 deficient mice.
Recent studies reveal that AKT2 (zeige AKT2 Antikörper)-NOX2 signaling has critical roles in Ca mobilization, ROS (zeige ROS1 Antikörper) generation, degranulation, and control of the ligand-binding function of cell surface molecules, thereby promoting heterotypic cell-cell interactions in thromboinflammation.
Study demonstrate that Nox2 signaling via inactivation of phosphatase and tensin homolog (zeige PTEN Antikörper) and activation of the PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) pathway leads to membrane ruffling and macropinocytosis.
Our findings indicate that Nox2 deficiency results in exaggerated experimental asthma, which is caused by enhanced Th2 effector function in a T-cell-intrinsic manner.
In a family study of a patient with chronic granulomatous disease, the mutation in the CYBB gene was confirmed to be pathogenic, and the three variants in the CYBA (zeige CYBA Antikörper) gene were benign.
Finally, overexpression of miR34a in EBNA1 (zeige EBNA-1 Antikörper)-expressing SNU719 cells induced typical apoptosis, suggesting that reactivation of miR34a in EBNA1 (zeige EBNA-1 Antikörper)-expressing gastric cancer cells could be a strategy for treatment of EBV-infected gastric cancer cells.
NOX2 expression was significantly higher in the cortex of asphyctic suicide subjects than in non-suicidal asphyxia and controls.
Acute myeloid leukemia (zeige BCL11A Antikörper) cells -derived NOX2 drives transfer of mitochondria via the generation of superoxide.
NOX2, NOX4 (zeige NOX4 Antikörper), and mitochondrial-derived reactive oxygen species contribute to angiopoietin-1 (zeige ANGPT1 Antikörper) signaling and angiogenic responses in endothelial cells.
Data indicate that the efficiency of NADPH oxidase (zeige NOX1 Antikörper) enzymatic activity is higher at endoplasmic reticulum (ER).
A p47(phox) and Src kinase (zeige CSK Antikörper) activation of peroxide production by Nox2 appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C (zeige PKC Antikörper)
this study shows that neutrophil pyroptosis mediates pathology of Pseudomonas aeruginosa lung infection in the absence of the NADPH oxidase (zeige NOX1 Antikörper) NOX2
Data indicate that increased NADPH oxidase (zeige NOX1 Antikörper) activity after traumatic brain injury drives M1-like activation in microglia/macrophages that contributes to inflammatory-mediated neurodegeneration.
Neurofibromin (zeige NF1 Antikörper) regulates macrophage superoxide production via p21Ras.Neurofibromin-deficient smooth muscle cells are sensitive to oxidative stress.NADPH oxidase 2 is required for NF1 (zeige NF1 Antikörper) arterial stenosis.Neurofibromatosis type 1 patients have evidence of chronic oxidative stress.
We examined the pattern of NOX expression in spinal cords of patients and mouse models of ALS and analyzed the impact of genetic deletion of the NOX1 (zeige NOX1 Antikörper) and 2 isoforms as well as pharmacological NOX inhibition in the SOD1 (zeige SOD1 Antikörper)(G93A) ALS mouse model.In contrast to previous publications, survival of SOD1 (zeige SOD1 Antikörper)(G93A) mice was not modified upon breeding with constitutive NOX1 (zeige NOX1 Antikörper) and NOX2 deficient mice.
Spinal cord injury leads to a significant increase in NOX2 expression. The reduction in M2 polarization is associated with a peak in NOX2 expression.
NOX2 has a role in leukocyte activation and in thrombus formation
mice deficient in reactive oxygen species production by NOX2 due to the absence of the gp91 (zeige LILRB3 Antikörper) subunit had significantly more severe pathology in the later stages of infection with Leishmania amazonensis
indicate that following traumatic brain injury NOX2 inhibition promotes a robust anti-inflammatory response in macrophages/microglia that is mediated by the IL-10 (zeige IL10 Antikörper)/STAT3 (zeige STAT3 Antikörper) signaling pathway
The results suggest that Nrf2 (zeige NFE2L2 Antikörper) is an important regulator of the retinal milieu during tissue ischemia, and that the Nrf2 (zeige NFE2L2 Antikörper)/NOX2 balance may play a critical role in determining the fate of ischemic revascularization.
North American ginseng inhibits myocardial NOX2-ERK1/2 (zeige MAPK1/3 Antikörper)-TNF-alpha (zeige TNF Antikörper) signaling pathway and improves cardiac function in endotoxemia, suggesting that NA ginseng may have the potential in the prevention of clinical sepsis.
These results suggested that resveratrol strongly enhances the RA-induced O2(-)-generating activity via up-regulation of gp91-phox gene expression in U937 cells.
sub-vasomotor concentration of ET-1 (zeige EDN1 Antikörper) leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 (zeige MAPK14 Antikörper) kinase-mediated production of superoxide from NADPH oxidase (zeige NOX1 Antikörper) following ETA receptor activation
Reactive oxygen species generated by NADPH oxidase (zeige NOX1 Antikörper) contribute to the aberrant pulmonary arterial responses in piglets exposed to 3 days of hypoxia.
Upregulation of PPAR-gamma and NADPH oxidases are involved in restenosis.
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase\; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.
cytochrome b-245, beta polypeptide
, NADPH oxidase 2
, cytochrome b-245, beta polypeptide (chronic granulomatous disease)
, Cytochrome b-245 heavy chain
, NADPH oxidase heavy chain subunit
, NADPH oxidase 1
, NADPH oxidase flavocytochrome b subunit
, cytochrome b-245 heavy chain
, cytochrome b(558) subunit beta
, cytochrome b558 subunit beta
, heme-binding membrane glycoprotein gp91phox
, neutrophil cytochrome b 91 kDa polypeptide
, p22 phagocyte B-cytochrome
, superoxide-generating NADPH oxidase heavy chain subunit
, endothelial type gp91-phox
, predicted NADPH oxidase-2