Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1) ELISA Kits

The protein encoded by CDK2AP1 is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Zusätzlich bieten wir Ihnen Cyclin-Dependent Kinase 2 Associated Protein 1 Antikörper (57) und Cyclin-Dependent Kinase 2 Associated Protein 1 Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
CDK2AP1 13445 O35207
CDK2AP1 8099 O14519
Anti-Ratte CDK2AP1 CDK2AP1 360804  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
Details
Maus < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
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Weitere ELISA Kits für Cyclin-Dependent Kinase 2 Associated Protein 1 Interaktionspartner

Mouse (Murine) Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1) Interaktionspartner

  1. Cdk2ap1 expression is primarily regulated by progesterone and the progesterone receptor (zeige PGR ELISA Kits) in uterus and is mainly localized to proliferating tissues.

  2. Results indicate that DOC-1 (zeige CA6 ELISA Kits) is a bona fide subunit of the Mi-2 (zeige CHD4 ELISA Kits)/NuRD chromatin remodeling complex.

  3. (CDK2 (zeige CDK2 ELISA Kits)-AP1 (zeige JUN ELISA Kits)) is a potential gene therapeutic agent for oral/head and neck cancer in conjunction with DNA-damaging agents such as cisplatin.

  4. p12CDK2-AP1 (zeige JUN ELISA Kits) forms nuclear homodimers in contact inhibited normal diploid cells and dimerization of p12 is a necessary process for the growth inhibition effect by p12

  5. Results suggest that overexpression of CDK2 (zeige CDK2 ELISA Kits)-associating protein 1 (p12CDK2AP1) leads to testicular and ovarian abnormalities, a phenotype closely related to that of cdk2 (zeige CDK2 ELISA Kits)-/- mice.

  6. Cdk2ap1, a negative regulator of Cdk2 (zeige CDK2 ELISA Kits) function and cell cycle, promotes Oct4 (zeige POU5F1 ELISA Kits) promoter methylation during murine embryonic stem cell differentiation to down-regulate Oct4 (zeige POU5F1 ELISA Kits) expression.

  7. Cdk2ap1 plays an essential role in the early stage of embryogenesis and has a potential role during craniofacial morphogenesis.

  8. CDK2AP1-mediated differentiation of murine embryonic stem cell was elicited through the regulation of pRb (zeige PGR ELISA Kits).

Human Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1) Interaktionspartner

  1. Knockdown of CDK2AP1 in hESCs results in increased p53 (zeige TP53 ELISA Kits) and enhances differentiation and favors it over a self-renewal fate.

  2. DOC1 re-expression in oral cancer cells causes a reversal of EMT. DOC1 promotes NURD binding to a subset of target loci.

  3. The simultaneous overexpression of p12CDK2-AP1 (zeige FOSB ELISA Kits) and CD82 (zeige CD82 ELISA Kits) significantly suppressed the in vivo tumor growth.

  4. knockdown of CDK2AP1 in primary human fibroblasts reduced proliferation and induced premature senescence, with the observed phenotype being p53 (zeige TP53 ELISA Kits) dependent

  5. In summary, p12CDK2AP1 expression in myxofibrosarcoma cells induces G0/G1 arrest and mitochondria dependent proapoptotic activity and down-regulation of p12CDK2AP1 by shRNAi results in up-regulation of the CDK2 (zeige CDK2 ELISA Kits) transcript and protein.

  6. Study reports that knockdown of CDK2AP1 by RNAi in glioma cells could effectively inhibit cell proliferation by inducing cell cycle arrest and apoptosis

  7. CDK2AP1 plays an important role in modulating the growth and tumorigenesis of lung cancer cells.

  8. Low CDK2AP1 expression is common and associated with adverse prognosis in nasopharyngeal carcinoma.

  9. Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region

  10. In comparison with the healthy gingiva, the expression of Doc-1 was decreased, whereas the expression of S100A7 (zeige S100A7 ELISA Kits) was upregulated in all oral lesions.

Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Genbezeichner und Symbole assoziert mit CDK2AP1

  • cyclin-dependent kinase 2 associated protein 1 S homeolog (cdk2ap1.S) Antikörper
  • cyclin dependent kinase 2 associated protein 1 (CDK2AP1) Antikörper
  • cyclin dependent kinase 2 associated protein 1 pseudogene (LOC475806) Antikörper
  • cyclin-dependent kinase 2 associated protein 1 (cdk2ap1) Antikörper
  • CDK2 (cyclin-dependent kinase 2)-associated protein 1 (Cdk2ap1) Antikörper
  • cyclin-dependent kinase 2 associated protein 1 (Cdk2ap1) Antikörper
  • cyclin dependent kinase 2 associated protein 1 (Cdk2ap1) Antikörper
  • Apc10 Antikörper
  • Cdkap1 Antikörper
  • doc-1 Antikörper
  • DOC1 Antikörper
  • DORC1 Antikörper
  • MGC64532 Antikörper
  • p12 Antikörper
  • p12DOC-1 Antikörper
  • ST19 Antikörper

Bezeichner auf Proteinebene für CDK2AP1

cyclin-dependent kinase 2 associated protein 1 , CDK2-associated protein 1 , CDK2 (cyclin-dependent kinase 2)-associated protein 1 , cyclin-dependent kinase 2-associated protein 1 , CDK2-associated protein1 , deleted in oral cancer 1 , putative oral cancer suppressor , Deleted in oral cancer-1

GENE ID SPEZIES
380551 Xenopus laevis
452342 Pan troglodytes
475806 Canis lupus familiaris
549484 Xenopus (Silurana) tropicalis
615387 Bos taurus
704412 Macaca mulatta
100153712 Sus scrofa
13445 Mus musculus
8099 Homo sapiens
360804 Rattus norvegicus
101825251 Mesocricetus auratus
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